Published in:
01-10-2014 | Editorial
How nescience may obscure evidence
Authors:
Prof. Dr. med. M.-L. Sautter-Bihl, F. Sedlmayer, W. Budach, J. Dunst, P. Feyer, R. Fietkau, W. Haase, W. Harms, M.D. Piroth, R. Souchon, F. Wenz, R. Sauer, Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO)
Published in:
Strahlentherapie und Onkologie
|
Issue 10/2014
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Excerpt
During the last decade, treatment trends for early breast cancer have been fluctuating between opposite extremes. More aggressive regional nodal irradiation (RNI) has been suggested by several recent studies [
10,
17], on the other side, the previously unquestioned dogma of axillary dissection as an important part of breast cancer management was gradually abandoned in favor of sentinel node dissection (SLND). While consensus was rapidly achieved for pathologically negative SN, the management of patients with one or two positive SN remained controversial up to the first publication of a randomized study of the American College of Surgeons Oncology Group [
3] which specifically addressed the outcome of such patients with ALND vs. none. Even though limitations of the study were recognized and let to some critical comments [
7], current guidelines [
8,
14] rapidly adopted the omission of ALND in these selected patients. …