Skip to main content
Top
Published in: International Journal of Public Health 7/2020

01-09-2020 | Human Papillomavirus | Review

Economic evaluation of human papillomavirus vaccination in the Global South: a systematic review

Authors: Saba Abidi, Satyanarayana Labani, Aastha Singh, Smita Asthana, Puneeta Ajmera

Published in: International Journal of Public Health | Issue 7/2020

Login to get access

Abstract

Objectives

Many reviews have been conducted on the economic evaluation of the HPV vaccine in global north countries. But there is a dearth of such reviews in the Global South countries. Hence, this systematic review aims to summarize studies done in these countries.

Methods

Four databases PubMed, Embase, Cochrane Library, and Google Scholar from 2009 to 2019 were searched for economic evaluations on HPV vaccination in the Global South countries. PRISMA guidelines were followed to include full-text articles. 40 original articles were shortlisted for full-text review.

Results

Studies had varied models, assumptions, and results according to different scenarios. Most studies concluded HPV vaccination to be cost-effective under varied scenarios and vaccine cost was the most influential parameter affecting the sensitivity analyses, consequently incremental cost-effectiveness ratio. A wide range in the cost-effectiveness ratio was observed in the included studies due to different study settings, populations, and inconsistencies in modeling practices (variations in methodological approaches).

Conclusions

This review suggests the introduction of HPV vaccination alone or in combination with screening according to different countries. The price of the vaccine should be economical and funds for the vaccine should be provided by public sector firms.
Appendix
Available only for authorised users
Literature
go back to reference Drummond M et al (1997) Methods for the economic evaluation of health care programs, 2nd edn. Oxford University Press, Oxford Drummond M et al (1997) Methods for the economic evaluation of health care programs, 2nd edn. Oxford University Press, Oxford
go back to reference Ezat SWP, Aljunid S (2010a) Comparative cost-effectiveness of HPV vaccines in the prevention of cervical cancer in Malaysia. Asian Pac J Cancer Prev 11:943–951PubMed Ezat SWP, Aljunid S (2010a) Comparative cost-effectiveness of HPV vaccines in the prevention of cervical cancer in Malaysia. Asian Pac J Cancer Prev 11:943–951PubMed
go back to reference Ezat SWP, Aljunid S (2010b) Cost-effectiveness of HPV vaccination in the prevention of cervical cancer in Malaysia. Asian Pacific J Cancer Prev 11:79–90 Ezat SWP, Aljunid S (2010b) Cost-effectiveness of HPV vaccination in the prevention of cervical cancer in Malaysia. Asian Pacific J Cancer Prev 11:79–90
go back to reference Khatibi M, Reza H, Shahverdi Z, Reza H (2014) Cost-effectiveness evaluation of quadrivalent human papilloma virus vaccine for HPV-related disease in Iran. Iran J Pharm Res. 13:225–234PubMedPubMedCentral Khatibi M, Reza H, Shahverdi Z, Reza H (2014) Cost-effectiveness evaluation of quadrivalent human papilloma virus vaccine for HPV-related disease in Iran. Iran J Pharm Res. 13:225–234PubMedPubMedCentral
go back to reference Sinisgalli E, Bellini I, Indiani L et al (2015) HPV vaccination for boys? A systematic review of economic studies. Epidemiol Prev 39:51–58PubMed Sinisgalli E, Bellini I, Indiani L et al (2015) HPV vaccination for boys? A systematic review of economic studies. Epidemiol Prev 39:51–58PubMed
Metadata
Title
Economic evaluation of human papillomavirus vaccination in the Global South: a systematic review
Authors
Saba Abidi
Satyanarayana Labani
Aastha Singh
Smita Asthana
Puneeta Ajmera
Publication date
01-09-2020
Publisher
Springer International Publishing
Published in
International Journal of Public Health / Issue 7/2020
Print ISSN: 1661-8556
Electronic ISSN: 1661-8564
DOI
https://doi.org/10.1007/s00038-020-01431-1

Other articles of this Issue 7/2020

International Journal of Public Health 7/2020 Go to the issue