Skip to main content
Top
Published in: Netherlands Heart Journal 7/2007

01-07-2007 | case report

Pheochromocytoma mimicking an acute myocardial infarction

Authors: C. W. der Menke-van Houven van Oordt, h. B. Twickler, F. G. M. H. van Asperdt, P. Ackermans, A. R. R. M. Hermus

Published in: Netherlands Heart Journal | Issue 7/2007

Login to get access

Abstract

We report a 42-year-old female who presented with retrosternal pain, dyspnoea and nausea. Electrocardiography suggested a recent anterior myocardial infarction. However, emergency coronary angiography showed normal blood flow through all the coronary arteries. Paroxysmal hypertension raised the suspicion of a pheochromocytoma. Indeed, abdominal ultrasonography and computed tomography revealed a mass in the left adrenal gland. Elevated levels of plasma and urine catecholamines supported the diagnosis of pheochromocytoma. Left adrenalectomy was performed without complications and pathological examination revealed a 5.5 cm pheochromocytoma. After surgery, all antihypertensive medication was discontinued and the blood pressure returned to normal within several days. Currently, the patient is asymptomatic, has normal catecholamine levels and the electrocardiographic signs of ischaemia have resolved entirely. This case illustrates that a rare clinical entity such as pheochromocytoma should be considered in the differential diagnosis of acute coronary syndrome. (Neth Heart J 2007; 15:248-51.)
Literature
go back to reference Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet 2005;366:665-75. Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet 2005;366:665-75.
go back to reference Schurmeyer TH, Engeroff B, Dralle H, von zur Muhlen A. Cardiological effects of catecholamine-secreting tumours. Eur J Clin Invest 1997;27:189-95. Schurmeyer TH, Engeroff B, Dralle H, von zur Muhlen A. Cardiological effects of catecholamine-secreting tumours. Eur J Clin Invest 1997;27:189-95.
go back to reference Darze ES, Von Sohsten RL. Pheochromocytoma-induced segmental myocardial dysfunction mimicking an acute myocardial infarction in a patient with normal coronary arteries. Arq Bras Cardiol 2004;82:178-80. Darze ES, Von Sohsten RL. Pheochromocytoma-induced segmental myocardial dysfunction mimicking an acute myocardial infarction in a patient with normal coronary arteries. Arq Bras Cardiol 2004;82:178-80.
go back to reference Mauser M, Billmann P, Fleischmann D. Acute myocardial infarct in pheochromocytoma crisis. Early coronary angiography findings and echocardiography follow-up. Z Kardiol 2001;90:297-303. Mauser M, Billmann P, Fleischmann D. Acute myocardial infarct in pheochromocytoma crisis. Early coronary angiography findings and echocardiography follow-up. Z Kardiol 2001;90:297-303.
go back to reference De Backer TL, De Buyzere ML, Taeymans Y, Kunnen P, Rubens R, Clement DL. Cardiac involvement in pheochromocytoma. J Hum Hypertens 2000;14:469-71. De Backer TL, De Buyzere ML, Taeymans Y, Kunnen P, Rubens R, Clement DL. Cardiac involvement in pheochromocytoma. J Hum Hypertens 2000;14:469-71.
go back to reference Garg A, Banitt PF. Pheochromocytoma and myocardial infarction. South Med J 2004;97:981-4. Garg A, Banitt PF. Pheochromocytoma and myocardial infarction. South Med J 2004;97:981-4.
go back to reference Dinckal MH, Davutoglu V, Soydinc S, Kirilmaz A. Phaeochromocytoma-induced myocarditis mimicking acute myocardial infarction. Int J Clin Pract 2003;57:842-3. Dinckal MH, Davutoglu V, Soydinc S, Kirilmaz A. Phaeochromocytoma-induced myocarditis mimicking acute myocardial infarction. Int J Clin Pract 2003;57:842-3.
go back to reference Serfas D, Shoback DM, Lorell BH. Phaeochromocytoma and hypertrophic cardiomyopathy: apparent suppression of symptoms and noradrenaline secretion by calcium-channel blockade. Lancet 1983;352:711-3. Serfas D, Shoback DM, Lorell BH. Phaeochromocytoma and hypertrophic cardiomyopathy: apparent suppression of symptoms and noradrenaline secretion by calcium-channel blockade. Lancet 1983;352:711-3.
go back to reference Magalhaes LC, Darze ES, Ximenes A, Santana O, Bastos J, Guimaraes A. Acute myocarditis secondary to pheochromocytoma. Arq Bras Cardiol 2004;83:346-8. Magalhaes LC, Darze ES, Ximenes A, Santana O, Bastos J, Guimaraes A. Acute myocarditis secondary to pheochromocytoma. Arq Bras Cardiol 2004;83:346-8.
go back to reference Elsman P, Alleman MA, Zijlstra F. [Clinical presentations mimicking acute myocardial infarction; therapeutic pitfalls]. Ned Tijdschr Geneeskd 1998;142:1057-60. Elsman P, Alleman MA, Zijlstra F. [Clinical presentations mimicking acute myocardial infarction; therapeutic pitfalls]. Ned Tijdschr Geneeskd 1998;142:1057-60.
go back to reference Kawasaki T, Azuma A, Sawada T, et al. Electrocardiographic score as a predictor of mortality after subarachnoid hemorrhage. Circ J 2002;66:567-70. Kawasaki T, Azuma A, Sawada T, et al. Electrocardiographic score as a predictor of mortality after subarachnoid hemorrhage. Circ J 2002;66:567-70.
go back to reference Bybee KA, Kara T, Prasad A, et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 2004;141:858-65. Bybee KA, Kara T, Prasad A, et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 2004;141:858-65.
go back to reference Higashi Y, Sasaki S, Nakagawa K, et al. Excess norepinephrine impairs both endothelium-dependent and –independent vasodilation in patients with pheochromocytoma. Hypertension 2002;39:513-8. Higashi Y, Sasaki S, Nakagawa K, et al. Excess norepinephrine impairs both endothelium-dependent and –independent vasodilation in patients with pheochromocytoma. Hypertension 2002;39:513-8.
go back to reference Calcagni E, Elenkov I. Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases. Ann N Y Acad Sci 2006;1069:62-76. Calcagni E, Elenkov I. Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases. Ann N Y Acad Sci 2006;1069:62-76.
go back to reference Bernini G, Franzoni F, Galetta F, Moretti A, Taurino C, Bardini M, et al. Carotid vascular remodeling in patients with pheochromocytoma. J Clin Endocrinol Metab 2006;91:1754-60. Bernini G, Franzoni F, Galetta F, Moretti A, Taurino C, Bardini M, et al. Carotid vascular remodeling in patients with pheochromocytoma. J Clin Endocrinol Metab 2006;91:1754-60.
Metadata
Title
Pheochromocytoma mimicking an acute myocardial infarction
Authors
C. W. der Menke-van Houven van Oordt
h. B. Twickler
F. G. M. H. van Asperdt
P. Ackermans
A. R. R. M. Hermus
Publication date
01-07-2007
Publisher
Bohn Stafleu van Loghum
Published in
Netherlands Heart Journal / Issue 7/2007
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03085991

Other articles of this Issue 7/2007

Netherlands Heart Journal 7/2007 Go to the issue