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Journal of Nephrology
Published in: Journal of Nephrology 4/2016

01-08-2016 | Review

IgA nephropathy and infections

Authors: Cristiana Rollino, Gisella Vischini, Rosanna Coppo

Published in: Journal of Nephrology | Issue 4/2016

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Abstract

In this paper we concentrate on the role of infections in IgA nephropathy both from a pathogenetic and clinic point of view. The current hypotheses as regards the role of infections in the pathogenesis of IgA nephropathy are: (a) role of particular pathogens, (b) chronic exposure to mucosal infections, (c) abnormal handling of commensal microbes (gut microbiota). We also focus on particular infections reported in association with classic IgA nephropathy (HIV, malaria, Chlamydia, Lyme disease), as well as on IgA dominant-infection-associated glomerulonephritis. This is a unique form of glomerulonephritis, where IgA deposition is dominant. It is mostly recognized in old, diabetic patients and in association with staphylococcal infection.
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Metadata
Title
IgA nephropathy and infections
Authors
Cristiana Rollino
Gisella Vischini
Rosanna Coppo
Publication date
01-08-2016
Publisher
Springer International Publishing
Published in
Journal of Nephrology / Issue 4/2016
Print ISSN: 1121-8428
Electronic ISSN: 1724-6059
DOI
https://doi.org/10.1007/s40620-016-0265-x

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