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Published in: Reactions Weekly 1/2023

01-12-2023 | Ritonavir | News item

Paxlovid: risk of drug interactions

Published in: Reactions Weekly | Issue 1/2023

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Excerpt

The UK Medicines and Healthcare products Regulatory Agency (MHRA) is advising healthcare professionals that there is a risk of potentially harmful drug interactions with the ritonavir component of the COVID-19 treatment Paxlovid (nirmatrelvir+ritonavir) due to its inhibition of the enzyme CYP3A4, which metabolises many commonly used drugs and may lead to increased toxicity from concomitant medications or reduced effectiveness of Paxlovid. …
Metadata
Title
Paxlovid: risk of drug interactions
Publication date
01-12-2023
Publisher
Springer International Publishing
Keyword
Ritonavir
Published in
Reactions Weekly / Issue 1/2023
Print ISSN: 0114-9954
Electronic ISSN: 1179-2051
DOI
https://doi.org/10.1007/s40278-023-50774-x

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