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Current Obesity Reports
Published in: Current Obesity Reports 1/2014

Open Access 01-03-2014 | Etiology of Obesity (MS Westerterp-Plantenga, Section Editor)

Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights

Authors: Jean-Philippe Chaput, Louis Pérusse, Jean-Pierre Després, Angelo Tremblay, Claude Bouchard

Published in: Current Obesity Reports | Issue 1/2014

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Abstract

The Quebec Family Study (QFS) was an observational study with three cycles of data collection between 1979 and 2002 in Quebec City, Canada. The cohort is a mixture of random sampling and ascertainment through obese individuals. The study has significantly contributed to our understanding of the determinants of obesity and associated disease risk over the past 35 years. In particular, the QFS cohort was used to investigate the contribution of familial resemblance and genetic effects on body fatness and behaviors related to energy balance. Significant familial aggregation and genetic heritability were reported for total adiposity, fat-free mass, subcutaneous fat distribution, abdominal and visceral fat, resting metabolic rate, physical activity level and other behavioral traits. The resources of QFS were also used to study the contribution of several nontraditional (non-caloric) risk factors as predictors of excess body weight and gains in weight and adiposity over time, including low calcium and micronutrient intake, high disinhibition eating behavior trait, and short sleep duration. An important finding relates to the interactions between dietary macronutrient intake and exercise intensity on body mass and adiposity.
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Metadata
Title
Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights
Authors
Jean-Philippe Chaput
Louis Pérusse
Jean-Pierre Després
Angelo Tremblay
Claude Bouchard
Publication date
01-03-2014
Publisher
Springer US
Published in
Current Obesity Reports / Issue 1/2014
Electronic ISSN: 2162-4968
DOI
https://doi.org/10.1007/s13679-013-0086-3

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