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Dermatology and Therapy

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Open Access 01-12-2021 | Lymphoma | Review

A Comprehensive Update of the Atypical, Rare and Mimicking Presentations of Mycosis Fungoides

Authors: Eve Lebas, Patrick Collins, Joan Somja, Arjen F. Nikkels

Published in: Dermatology and Therapy | Issue 6/2021

Abstract

Introduction

Mycosis fungoides (MF) is the most frequent subtype of primary cutaneous T cell lymphomas (pCTCL). The diagnosis may be particularly difficult in the early stages as well as in atypical and rare clinical presentations. Furthermore, MF may simulate a large variety of common dermatologic disorders and patterns, both histopathologically and clinically.

Methods

A literature search was performed to provide a comprehensive update on the rare and atypical MF manifestations as well as the dermatoses and dermatological patterns that could be imitated by MF.

Results

A total of 114 publications were found describing a series of different dermatoses and dermatological patterns mimicked by MF, as well as some particular localizations of MF lesions and dermatoses that occur in preexisting MF lesions.

Conclusions

The number of dermatoses that can be imitated by MF is ever-increasing. Patients with common dermatologic conditions that prove to be treatment refractory should be biopsied without delay, and sequentially as necessary, to prevent delay in diagnosis and progression of disease. Clinicopathologic correlation is the best way of diagnosis.

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Title: A Comprehensive Update of the Atypical, Rare and Mimicking Presentations of Mycosis Fungoides
Authors: Eve Lebas
Patrick Collins
Joan Somja
Arjen F. Nikkels
Publication date: 01-12-2021
Publisher: Springer Healthcare
Keywords: Lymphoma
Mycosis Fungoides
Published in: Dermatology and Therapy / Issue 6/2021
Print ISSN: 2193-8210
Electronic ISSN: 2190-9172
DOI: https://doi.org/10.1007/s13555-021-00625-6

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