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International Journal of Diabetes in Developing Countries

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15-02-2023 | Diabetic Neuropathy | Original Article

TNF-α levels, hypertension, glycated hemoglobin, and lower limb pain are predictors of diabetic neuropathy

Authors: Luciano Ramos de Lima, Marina Morato Stival, Silvana Schwerz Funghetto, Cris Renata Grou Volpe, Izabel Cristina Rodrigues da Silva, Calliandra Maria de Souza Silva, Alessandro de Oliveira Silva, Mani Indiana Funez

Published in: International Journal of Diabetes in Developing Countries | Issue 5/2023

Excerpt

Diabetic neuropathy (DN) is one of the main complications of diabetes mellitus (DM), affecting up to 50% of patients. DN causes progressive nerve degeneration and ranges from asymptomatic to physically disabling. Patients with DN may have neuronal damage, sensory neuron changes, and peripheral nerve involvement, with pain also reported, especially in type 2 DM (T2DM) patients. However, the diagnosis is often late, contributing to ulcer formation and up to 70% of limb amputations [1, 2], affecting the DM patients’ quality of life [3, 4]. …

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Title: TNF-α levels, hypertension, glycated hemoglobin, and lower limb pain are predictors of diabetic neuropathy
Authors: Luciano Ramos de Lima
Marina Morato Stival
Silvana Schwerz Funghetto
Cris Renata Grou Volpe
Izabel Cristina Rodrigues da Silva
Calliandra Maria de Souza Silva
Alessandro de Oliveira Silva
Mani Indiana Funez
Publication date: 15-02-2023
Publisher: Springer India
Keywords: Diabetic Neuropathy
Diabetic Neuropathy
Hypertension
Cytokines
Diabetes
Published in: International Journal of Diabetes in Developing Countries / Issue 5/2023
Print ISSN: 0973-3930
Electronic ISSN: 1998-3832
DOI: https://doi.org/10.1007/s13410-023-01170-y

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