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Published in:

01-02-2015 | Review

Long non-coding RNAs in cancer: implications for personalized therapy

Authors: Marianna Vitiello, Andrea Tuccoli, Laura Poliseno

Published in: Cellular Oncology | Issue 1/2015

Abstract

Long non-coding RNAs (lncRNAs, pseudogenes and circRNAs) have recently come into light as powerful players in cancer pathogenesis and it is becoming increasingly clear that they have the potential of greatly contributing to the spread and success of personalized cancer medicine. In this concise review, we briefly introduce these three classes of long non-coding RNAs. We then discuss their applications as diagnostic and prognostic biomarkers. Finally, we describe their appeal as targets and as drugs, while pointing out the limitations that still lie ahead of their definitive entry into clinical practice.

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Title: Long non-coding RNAs in cancer: implications for personalized therapy
Authors: Marianna Vitiello
Andrea Tuccoli
Laura Poliseno
Publication date: 01-02-2015
Publisher: Springer Netherlands
Published in: Cellular Oncology / Issue 1/2015
Print ISSN: 2211-3428
Electronic ISSN: 2211-3436
DOI: https://doi.org/10.1007/s13402-014-0180-x

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