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Published in: Diabetology International 4/2012

01-12-2012 | Report of the committee

Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus: New Diagnostic Criteria of Fulminant Type 1 Diabetes Mellitus (2012)

Authors: Akihisa Imagawa, Toshiaki Hanafusa, Takuya Awata, Hiroshi Ikegami, Yasuko Uchigata, Haruhiko Osawa, Eiji Kawasaki, Yumiko Kawabata, Tetsuro Kobayashi, Akira Shimada, Ikki Shimizu, Kazuma Takahashi, Masao Nagata, Hideichi Makino, Taro Maruyama

Published in: Diabetology International | Issue 4/2012

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Abstract

We have revised a part of the diagnostic criteria for fulminant type 1 diabetes. The new criteria were set both to express the essence of this disease of rapid increase of patients’ blood glucose and to be highly sensitive to reduce the misdiagnosis. After analyzing the data of 382 patients with newly-diagnosed fulminant type 1 diabetes, we adopted the HbA1c level of 8.7 % (NGSP value). The new criterion indicates 100 % of sensitivity and best value by ROC (receiver operation curve) analysis. In addition, we added a comment that “This value (HbA1c < 8.7 % in NGSP) is not applicable for patients with previously diagnosed glucose intolerance” on the new criteria and also a comment that “Association with HLA DRB1*04:05-DQB1*04:01 is reported” as a related finding. We did not revise the screening criteria and the other part of the diagnostic criteria, because they are still reliable.
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Metadata
Title
Report of the Committee of the Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus: New Diagnostic Criteria of Fulminant Type 1 Diabetes Mellitus (2012)
Authors
Akihisa Imagawa
Toshiaki Hanafusa
Takuya Awata
Hiroshi Ikegami
Yasuko Uchigata
Haruhiko Osawa
Eiji Kawasaki
Yumiko Kawabata
Tetsuro Kobayashi
Akira Shimada
Ikki Shimizu
Kazuma Takahashi
Masao Nagata
Hideichi Makino
Taro Maruyama
Publication date
01-12-2012
Publisher
Springer Japan
Published in
Diabetology International / Issue 4/2012
Print ISSN: 2190-1678
Electronic ISSN: 2190-1686
DOI
https://doi.org/10.1007/s13340-012-0098-3

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