Skip to main content
Top
Published in: Updates in Surgery 1/2017

01-03-2017 | Original Article

Long-term effects of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for the treatment of morbid obesity: a monocentric prospective study with minimum follow-up of 5 years

Authors: Federico Perrone, Emanuela Bianciardi, Simona Ippoliti, Jennifer Nardella, Francesco Fabi, Paolo Gentileschi

Published in: Updates in Surgery | Issue 1/2017

Login to get access

Abstract

Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most widely used bariatric procedures nowadays. The aim of this study was to compare long-term results on weight loss and comorbidities improvement for both procedures. A cohort of 304 consecutive patients underwent surgery in 2006–2009: 162 underwent LSG and 142 underwent LRYGB. The mean follow-up time was 75.8 ± 8.4 months (range 60–96). LSG showed greater effectiveness in percentage of excess weight loss (%EWL) at 180 days and at 1 year of follow-up. Instead, at 5th year follow-up LRYGB and LSG showed similar %EWL values (72.34 versus 70.26). LSG group showed a lack of weight loss in patients from 3 to 5 years after surgery, whereas LRYGB group patients maintained an effective weight loss during the entire follow-up period. In LSG group both length of stay and operative time were found to be shorter. LRYGB showed better effectiveness in type 2 diabetes mellitus (T2DM) resolution rate. None of the two techniques has proven to be clearly better than the other on a long-term follow-up analysis, except for the LRYGB better results in T2DM healing. According to our findings, in LSG Group after 3 years the weight remains stable.
Literature
1.
go back to reference Fontaine KR, Redden DT, Wang C et al (2003) Years of life lost due to obesity. J Am Med Assoc 289(2):187–193CrossRef Fontaine KR, Redden DT, Wang C et al (2003) Years of life lost due to obesity. J Am Med Assoc 289(2):187–193CrossRef
2.
go back to reference Yanovski SZ (2000) Overweight, obesity, and health risk: National Task Force on the Prevention and Treatment of Obesity. Arch Intern Med 160(7):898–904CrossRef Yanovski SZ (2000) Overweight, obesity, and health risk: National Task Force on the Prevention and Treatment of Obesity. Arch Intern Med 160(7):898–904CrossRef
3.
go back to reference Franco JVA, Ruiz PA, Palermo M et al (2011) A review of studies comparing three laparoscopic procedures in bariatric surgery: sleeve gastrectomy, Roux-en-Y gastric bypass and adjustable gastric banding. Obes Surg 21(9):1458–1468CrossRefPubMed Franco JVA, Ruiz PA, Palermo M et al (2011) A review of studies comparing three laparoscopic procedures in bariatric surgery: sleeve gastrectomy, Roux-en-Y gastric bypass and adjustable gastric banding. Obes Surg 21(9):1458–1468CrossRefPubMed
4.
go back to reference Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and metanalysis. JAMA 292(14):1724–1737CrossRefPubMed Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and metanalysis. JAMA 292(14):1724–1737CrossRefPubMed
5.
go back to reference Sjöström L, Lindroos AK, Peltonen M et al (2004) Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 351(26):2683–2693CrossRefPubMed Sjöström L, Lindroos AK, Peltonen M et al (2004) Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 351(26):2683–2693CrossRefPubMed
6.
go back to reference Mingrone G, Panunzi S, De Gaetano A et al (2012) Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 366:1577–1585CrossRefPubMed Mingrone G, Panunzi S, De Gaetano A et al (2012) Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 366:1577–1585CrossRefPubMed
7.
go back to reference Flum DR, Belle SH, King WC et al (2009) Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 361:445–454CrossRefPubMed Flum DR, Belle SH, King WC et al (2009) Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 361:445–454CrossRefPubMed
9.
go back to reference Daskalakis M, Weiner RA (2009) Sleeve gastrectomy as a single stage bariatric operation: indications and limitations. Obes Facts 2(1):8–10CrossRefPubMed Daskalakis M, Weiner RA (2009) Sleeve gastrectomy as a single stage bariatric operation: indications and limitations. Obes Facts 2(1):8–10CrossRefPubMed
10.
go back to reference Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and meta-analysis. J Am Med Assoc 292(14):1724–1737CrossRef Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and meta-analysis. J Am Med Assoc 292(14):1724–1737CrossRef
11.
go back to reference Aggarwal S, Kini SU, Herron DM (2007) Laparoscopic sleeve gastrectomy for morbid obesity: a review. Surg Obes Relat Dis 3(2):189–194CrossRefPubMed Aggarwal S, Kini SU, Herron DM (2007) Laparoscopic sleeve gastrectomy for morbid obesity: a review. Surg Obes Relat Dis 3(2):189–194CrossRefPubMed
12.
go back to reference Felberbauer FX, Langer F, Shakeri-Manesch S et al (2008) Laparoscopic sleeve gastrectomy as an isolated bariatric procedure: intermediate-term results from a large series in three Austrian centers. Obes Surg 18(7):814–818CrossRefPubMed Felberbauer FX, Langer F, Shakeri-Manesch S et al (2008) Laparoscopic sleeve gastrectomy as an isolated bariatric procedure: intermediate-term results from a large series in three Austrian centers. Obes Surg 18(7):814–818CrossRefPubMed
13.
go back to reference Topart P, Becouarn G, Ritz P (2012) Comparative early outcomes of three laparoscopic bariatric procedures: sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch. Surg Obes Relat Dis 8(3):250–254CrossRefPubMed Topart P, Becouarn G, Ritz P (2012) Comparative early outcomes of three laparoscopic bariatric procedures: sleeve gastrectomy, Roux-en-Y gastric bypass, and biliopancreatic diversion with duodenal switch. Surg Obes Relat Dis 8(3):250–254CrossRefPubMed
14.
go back to reference Nguyen NT, Nguyen B, Gebhart A et al (2013) Changes in the makeup of bariatric surgery: a national increase in use of laparoscopic sleeve gastrectomy. J Am Coll Surg 216(2):252–257CrossRefPubMed Nguyen NT, Nguyen B, Gebhart A et al (2013) Changes in the makeup of bariatric surgery: a national increase in use of laparoscopic sleeve gastrectomy. J Am Coll Surg 216(2):252–257CrossRefPubMed
15.
go back to reference Nguyen NT, Root J, Zainabadi K et al (2005) Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery. Arch Surg 140(12):1198–1202CrossRefPubMed Nguyen NT, Root J, Zainabadi K et al (2005) Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery. Arch Surg 140(12):1198–1202CrossRefPubMed
16.
go back to reference Rutledge T, Adler S, Friedman R (2011) A prospective assessment of psychosocial factors among bariatric versus non-bariatric surgery candidates. Obes Surg 21(10):1570–1579CrossRefPubMed Rutledge T, Adler S, Friedman R (2011) A prospective assessment of psychosocial factors among bariatric versus non-bariatric surgery candidates. Obes Surg 21(10):1570–1579CrossRefPubMed
17.
go back to reference Kehagias I, Karamanakos SN, Argentou M et al (2011) Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI < 50 kg/m2. Obes Surg 21:1650–1656CrossRefPubMed Kehagias I, Karamanakos SN, Argentou M et al (2011) Randomized clinical trial of laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the management of patients with BMI < 50 kg/m2. Obes Surg 21:1650–1656CrossRefPubMed
18.
go back to reference Boza C, Gamboa C, Salinas J et al (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case control study and 3 years of follow-up. Surg Obes Relat Dis 8:243–249CrossRefPubMed Boza C, Gamboa C, Salinas J et al (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case control study and 3 years of follow-up. Surg Obes Relat Dis 8:243–249CrossRefPubMed
19.
go back to reference Leyba JL, Aulestia SN, Lopis SN (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study of 117 patients. Obes Surg 21:212–216CrossRefPubMed Leyba JL, Aulestia SN, Lopis SN (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study of 117 patients. Obes Surg 21:212–216CrossRefPubMed
20.
go back to reference Albeladi B, Bourbao-Tournois C, Hutan N (2013) Short- and midterm results between laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy for the treatment of morbid obesity. J Obes 2013:934653CrossRefPubMedPubMedCentral Albeladi B, Bourbao-Tournois C, Hutan N (2013) Short- and midterm results between laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy for the treatment of morbid obesity. J Obes 2013:934653CrossRefPubMedPubMedCentral
21.
go back to reference Vidal P, Ramon JM, Goday A et al (2013) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy as a definitive surgical procedure for morbid obesity. Mid-term results. Obes Surg 23:292–299CrossRefPubMed Vidal P, Ramon JM, Goday A et al (2013) Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy as a definitive surgical procedure for morbid obesity. Mid-term results. Obes Surg 23:292–299CrossRefPubMed
22.
go back to reference Peterli R, Borbely Y, Kern B et al (2013) Early results of the swiss multicentre bypass or sleeve study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass. Ann Surg 258:690–694CrossRefPubMedPubMedCentral Peterli R, Borbely Y, Kern B et al (2013) Early results of the swiss multicentre bypass or sleeve study (SM-BOSS): a prospective randomized trial comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass. Ann Surg 258:690–694CrossRefPubMedPubMedCentral
23.
24.
go back to reference Buchwald H, Estok R, Fahrbach K et al (2009) Weight and type 2 diabetes after bariatric surgery: systematic review and meta analysis. Am J Med 122(3):248.e5–256.e5CrossRef Buchwald H, Estok R, Fahrbach K et al (2009) Weight and type 2 diabetes after bariatric surgery: systematic review and meta analysis. Am J Med 122(3):248.e5–256.e5CrossRef
25.
go back to reference Fischer L, Hildebrandt C, Bruckner T et al (2012) Excessive weight loss after sleeve gastrectomy: a systematic review. Obes Surg 22:721–731CrossRefPubMed Fischer L, Hildebrandt C, Bruckner T et al (2012) Excessive weight loss after sleeve gastrectomy: a systematic review. Obes Surg 22:721–731CrossRefPubMed
26.
go back to reference Leyba JL, Aulestia SN, Llopis SN (2011) Laparoscopic Roux en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study of 117 patients. Obes Surg 21(2):212–216CrossRefPubMed Leyba JL, Aulestia SN, Llopis SN (2011) Laparoscopic Roux en-Y gastric bypass versus laparoscopic sleeve gastrectomy for the treatment of morbid obesity. A prospective study of 117 patients. Obes Surg 21(2):212–216CrossRefPubMed
27.
go back to reference Boza C, Gamboa C, Salinas J et al (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case–control study and 3 years of follow-up. Surg Obes Relat Dis 8(3):243–249CrossRefPubMed Boza C, Gamboa C, Salinas J et al (2012) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case–control study and 3 years of follow-up. Surg Obes Relat Dis 8(3):243–249CrossRefPubMed
28.
go back to reference Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21(2):146–150CrossRefPubMed Bellanger DE, Greenway FL (2011) Laparoscopic sleeve gastrectomy, 529 cases without a leak: short-term results and technical considerations. Obes Surg 21(2):146–150CrossRefPubMed
29.
go back to reference Li JF, Lai DD, Lin Z et al (2014) Comparison of the long-term results of Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis of randomized and nonrandomized trials. Surg Laparosc Endosc Percutan Tech 24:1–11CrossRefPubMed Li JF, Lai DD, Lin Z et al (2014) Comparison of the long-term results of Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis of randomized and nonrandomized trials. Surg Laparosc Endosc Percutan Tech 24:1–11CrossRefPubMed
30.
go back to reference Lakdawala MA, Bhasker A, Mulchandani D et al (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20(1):1–6CrossRefPubMed Lakdawala MA, Bhasker A, Mulchandani D et al (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20(1):1–6CrossRefPubMed
31.
go back to reference Helmio M, Victorzon M, Ovaska J et al (2012) SLEEVEPASS: a randomized prospective multicenter study comparing laparoscopic sleeve gastrectomy and gastric bypass in the treatment of morbid obesity: preliminary results. Surg Endosc 26(9):2521–2526CrossRefPubMed Helmio M, Victorzon M, Ovaska J et al (2012) SLEEVEPASS: a randomized prospective multicenter study comparing laparoscopic sleeve gastrectomy and gastric bypass in the treatment of morbid obesity: preliminary results. Surg Endosc 26(9):2521–2526CrossRefPubMed
32.
go back to reference Chouillard EK, Karaa A, Elkhoury M et al (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case-control study. Surg Obes Relat Dis 7(4):500–505CrossRefPubMed Chouillard EK, Karaa A, Elkhoury M et al (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case-control study. Surg Obes Relat Dis 7(4):500–505CrossRefPubMed
33.
go back to reference Choullard EK, Karaa A, Elkhoury M et al (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case–control study. Surg Obes Relat Dis 7:500–505CrossRef Choullard EK, Karaa A, Elkhoury M et al (2011) Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity: case–control study. Surg Obes Relat Dis 7:500–505CrossRef
34.
go back to reference Yaghoubian A, Tolan A, Stabile BE et al (2012) Laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy achieve comparable weight loss at 1 year. Am Surg 78:1325–1328PubMed Yaghoubian A, Tolan A, Stabile BE et al (2012) Laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy achieve comparable weight loss at 1 year. Am Surg 78:1325–1328PubMed
35.
go back to reference Lakdawala MA, Bhasker A, Mulchandani D et al (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20:1–6CrossRefPubMed Lakdawala MA, Bhasker A, Mulchandani D et al (2010) Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg 20:1–6CrossRefPubMed
36.
go back to reference Gill RS, Birch DW, Shi X et al (2010) Sleeve gastrectomy and type 2 diabetes mellitus: a systematic review. Surg Obes Relat Dis 6:707–713CrossRefPubMed Gill RS, Birch DW, Shi X et al (2010) Sleeve gastrectomy and type 2 diabetes mellitus: a systematic review. Surg Obes Relat Dis 6:707–713CrossRefPubMed
37.
go back to reference Trastulli S, Desiderio J, Guarino S et al (2013) Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis 9(5):816–830CrossRefPubMed Trastulli S, Desiderio J, Guarino S et al (2013) Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis 9(5):816–830CrossRefPubMed
38.
go back to reference Chikunguwo SM, Wolfe LG, Dodson P et al (2010) Analysis of factors associated with durable remission of diabetes after Roux-en-Y gastric bypass. Surg Obes Relat Dis 6:254–259CrossRefPubMed Chikunguwo SM, Wolfe LG, Dodson P et al (2010) Analysis of factors associated with durable remission of diabetes after Roux-en-Y gastric bypass. Surg Obes Relat Dis 6:254–259CrossRefPubMed
39.
go back to reference Arterburn DE, Bogart A, Sherwood NE et al (2013) A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass. Obes Surg 23:93–102CrossRefPubMedPubMedCentral Arterburn DE, Bogart A, Sherwood NE et al (2013) A multisite study of long-term remission and relapse of type 2 diabetes mellitus following gastric bypass. Obes Surg 23:93–102CrossRefPubMedPubMedCentral
40.
go back to reference Perrone F, Bianciardi E, Gentileschi P et al (2016) Gender influence on long-term weight loss and comorbidities after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass: a prospective study with a 5-year follow-up. Obes Surg 26(2):276–281CrossRefPubMed Perrone F, Bianciardi E, Gentileschi P et al (2016) Gender influence on long-term weight loss and comorbidities after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass: a prospective study with a 5-year follow-up. Obes Surg 26(2):276–281CrossRefPubMed
Metadata
Title
Long-term effects of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for the treatment of morbid obesity: a monocentric prospective study with minimum follow-up of 5 years
Authors
Federico Perrone
Emanuela Bianciardi
Simona Ippoliti
Jennifer Nardella
Francesco Fabi
Paolo Gentileschi
Publication date
01-03-2017
Publisher
Springer Milan
Published in
Updates in Surgery / Issue 1/2017
Print ISSN: 2038-131X
Electronic ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-017-0426-z

Other articles of this Issue 1/2017

Updates in Surgery 1/2017 Go to the issue