Published in:
17-12-2022 | Metastasis | Original Article
Luminal mapping reveals mesenteric predominance of colonic adenomas and adenocarcinomas
Published in: Indian Journal of Gastroenterology | Issue 6/2022
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Background
Previous studies have examined the relationship between colorectal tumor distribution and metastasis, but the tumor luminal location and associative risk factors promoting tumor growth remain unknown.
Methods
In this study, we mapped the luminal distribution of human colonic adenomas/adenocarcinomas and their association with various physiologic parameters.
Results
We identified a mesenteric predominance for colonic adenomas and adenocarcinomas.
Conclusion
The findings of this study raise the possibility of novel mechanistic pathways in the development of adenomas and subsequent transformation into adenocarcinomas.