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International Journal of Behavioral Medicine

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Open Access 01-08-2019 | Ulcerative Colitis

Illness Perceptions and Depression Are Associated with Health-Related Quality of Life in Youth with Inflammatory Bowel Disease

Authors: Luuk Stapersma, Gertrude van den Brink, Jan van der Ende, Alexander G. Bodelier, Herbert M. van Wering, Pamela C. W. M. Hurkmans, M. Luisa Mearin, Andrea E. van der Meulen–de Jong, Johanna C. Escher, Elisabeth M. W. J. Utens

Published in: International Journal of Behavioral Medicine | Issue 4/2019

Abstract

Background

In youth with inflammatory bowel disease (IBD), health-related quality of life (HRQOL) has been shown to be affected by individual disease factors and specific psychological factors. The innovative aim of this study is to examine the combined impact of psychological factors (illness perceptions, cognitive coping, anxiety, and depression) on HRQOL, over and above the associations of demographic and disease factors with HRQOL in youth with IBD.

Method

Data on clinical disease activity, illness perceptions, cognitive coping, anxiety, depression, and HRQOL were prospectively collected in 262 consecutive youth (age 10–20, 46.6% male) with confirmed IBD. Multiple linear regression analyses tested the associations of demographic, disease, and psychological variables with HRQOL in separate groups for Crohn’s disease (CD; N = 147) and ulcerative colitis and IBD unclassified (UC/IBD-U; N = 115), using age-specific validated instruments.

Results

In both disease groups, more negative illness perceptions (ß = − .412; ß = − .438, p < .001) and more depression (ß = − .454; ß = − .279, p < .001) were related to lower HRQOL. In the UC/IBD-U group, more anxiety was related to lower HRQOL (ß = − .201, p = .001). The model with the psychological variables explained a large and significant amount of variance in both groups: 74% and 83%, respectively (p < .001).

Conclusion

In 10–20-year-old IBD patients, negative illness perceptions and depression were significantly and more strongly associated with lower HRQOL than demographic and disease factors. Thus, it is important to integrate psychological factors in the treatment for IBD patients. To improve HRQOL in young IBD patients, psychological interventions should be targeted at negative illness perceptions and depression.

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Title: Illness Perceptions and Depression Are Associated with Health-Related Quality of Life in Youth with Inflammatory Bowel Disease
Authors: Luuk Stapersma
Gertrude van den Brink
Jan van der Ende
Alexander G. Bodelier
Herbert M. van Wering
Pamela C. W. M. Hurkmans
M. Luisa Mearin
Andrea E. van der Meulen–de Jong
Johanna C. Escher
Elisabeth M. W. J. Utens
Publication date: 01-08-2019
Publisher: Springer US
Keywords: Ulcerative Colitis
Crohn's Disease
Chronic Inflammatory Bowel Disease
Mood Disorders
Affective Disorder
Anxiety
Published in: International Journal of Behavioral Medicine / Issue 4/2019
Print ISSN: 1070-5503
Electronic ISSN: 1532-7558
DOI: https://doi.org/10.1007/s12529-019-09791-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Illness Perceptions and Depression Are Associated with Health-Related Quality of Life in Youth with Inflammatory Bowel Disease

Abstract

Background

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Method

Results

Conclusion

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