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Published in: International Journal of Behavioral Medicine 2/2018

01-04-2018

Validation of an Egyptian Arabic Version of Skindex-16 and Quality of Life Measurement in Egyptian Patients with Skin Disease

Authors: Nagwa Essa, Sara Awad, Mariam Nashaat

Published in: International Journal of Behavioral Medicine | Issue 2/2018

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Abstract

Purpose

To translate and cross-culturally adapt the Skindex-16, a brief skin-disease-specific QoL questionnaire, into Arabic for Egyptians and to evaluate its measurement properties in Egyptian patients with skin disease.

Method

Translation and cultural adaption were performed following guidelines for cross-cultural adaption of health-related quality of life measures. Subsequently, Skindex-16 was administered to 500 consecutive dermatological patients and 500 healthy persons for verification of its reliability and validity. Next, we examined the effect of skin disorders on QoL as well as influences of age, sex, socioeconomic level, education, and use of medication on skin disease-related QoL.

Results

The instrument showed high internal consistency reliability and good construct and content validity. The quality of life was most deteriorated in the emotional domain followed by symptoms domain (mean percentage score 55.5 ± 23.1 and 31.7 ± 26.8 respectively), while functioning was the least affected domain (mean percentage score 29.1 ± 26.8). Higher total Skindex-16 scores were observed for patients with psoriasis, urticaria, acne, and atopic dermatitis than those with vitiligo and alopecia areata. Educational level, social class, medication use, and family history influenced the impact of skin disease on overall QoL.

Conclusion

The adapted Egyptian Arabic version of Skindex-16 is valid and reliable; it showed that skin problems had a clinically significant impact on QoL in Egyptian patients.
Literature
1.
go back to reference Finlay AY. Quality of life measurement in dermatology: a practical guide. Br J Dermatol. 1997;136:305–14.CrossRefPubMed Finlay AY. Quality of life measurement in dermatology: a practical guide. Br J Dermatol. 1997;136:305–14.CrossRefPubMed
2.
go back to reference Jayaprakasam A, Darvay A, Osborne G, McGibbon D. Comparison of assessments of severity and quality of life in cutaneous disease. Clin Exp Dermatol. 2002;27(4):306–8.CrossRefPubMed Jayaprakasam A, Darvay A, Osborne G, McGibbon D. Comparison of assessments of severity and quality of life in cutaneous disease. Clin Exp Dermatol. 2002;27(4):306–8.CrossRefPubMed
3.
go back to reference Jones-Caballero M, Penas PF, Garcia-Diez A, Badia X, Chren MM. The Spanish version of Skindex-29: cultural adaptation and preliminary evidence of validity and equivalence with the original American version. Int J Dermatol. 2000;39:907–12.CrossRefPubMed Jones-Caballero M, Penas PF, Garcia-Diez A, Badia X, Chren MM. The Spanish version of Skindex-29: cultural adaptation and preliminary evidence of validity and equivalence with the original American version. Int J Dermatol. 2000;39:907–12.CrossRefPubMed
4.
go back to reference Hill J, Bird HA, Lawton CW, Wright V. The arthritis impact measurement scales: an anglicized version to assess the outcome of British patients with rheumatoid arthritis. Br J Rheumatol. 1990;29:193–6.CrossRefPubMed Hill J, Bird HA, Lawton CW, Wright V. The arthritis impact measurement scales: an anglicized version to assess the outcome of British patients with rheumatoid arthritis. Br J Rheumatol. 1990;29:193–6.CrossRefPubMed
5.
go back to reference Kleinman A, Eisenberg L, Good B. Culture, illness and care: clinical lessons from anthropologic and cross-cultural research. Ann Intern Med. 1978;88:251–8.CrossRefPubMed Kleinman A, Eisenberg L, Good B. Culture, illness and care: clinical lessons from anthropologic and cross-cultural research. Ann Intern Med. 1978;88:251–8.CrossRefPubMed
6.
go back to reference Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. Clin Epidemiol. 1993;46:1417–32.CrossRef Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. Clin Epidemiol. 1993;46:1417–32.CrossRef
7.
go back to reference Chren MM, Lasek RJ, Quinn M, Mostow EN, Zyzanski SJ. Skindex, a quality-of-life measure for patients with skin disease: reliability, validity, and responsiveness. J Invest Dermatol. 1996;107:707–13.CrossRefPubMed Chren MM, Lasek RJ, Quinn M, Mostow EN, Zyzanski SJ. Skindex, a quality-of-life measure for patients with skin disease: reliability, validity, and responsiveness. J Invest Dermatol. 1996;107:707–13.CrossRefPubMed
8.
go back to reference Chren MM, Lasek RJ, Flocke SA, Zyzanski SJ. Improved discriminative and evaluative capability of a refined version of Skindex, a quality of life instrument for patients with skin diseases. Arch Dermatol. 1997;133:1433–40.CrossRefPubMed Chren MM, Lasek RJ, Flocke SA, Zyzanski SJ. Improved discriminative and evaluative capability of a refined version of Skindex, a quality of life instrument for patients with skin diseases. Arch Dermatol. 1997;133:1433–40.CrossRefPubMed
9.
go back to reference Chren MM. The Skindex instruments to measure the effects of skin disease on quality of life. Dermatol Clin. 2012;30:231–6.CrossRefPubMed Chren MM. The Skindex instruments to measure the effects of skin disease on quality of life. Dermatol Clin. 2012;30:231–6.CrossRefPubMed
10.
go back to reference Chren MM, Lasek RJ, Sahay AP, Sands LP. Measurement properties of skindex-16: a brief quality of life measure for patients with skin diseases. J Cutan Med Surg. 2001;5:105–10.CrossRefPubMed Chren MM, Lasek RJ, Sahay AP, Sands LP. Measurement properties of skindex-16: a brief quality of life measure for patients with skin diseases. J Cutan Med Surg. 2001;5:105–10.CrossRefPubMed
11.
go back to reference Comrey LA, Lee HB. A first course in factor analysis. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates; 1992. Comrey LA, Lee HB. A first course in factor analysis. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates; 1992.
12.
go back to reference Mokkink LB, Terwee CB, Patrick DL, Alonso J, Stratford PW, Knol DL, et al. The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study. Qual Life Res. 2010;19:539–49.CrossRefPubMedPubMedCentral Mokkink LB, Terwee CB, Patrick DL, Alonso J, Stratford PW, Knol DL, et al. The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study. Qual Life Res. 2010;19:539–49.CrossRefPubMedPubMedCentral
13.
go back to reference Higaki Y, Kawamoto K, Kamo T, Horikawa N, Kawashima M, Chren MM. The Japanese version of Skindex-16: a brief quality-of-life measure for patients with skin diseases. Dermatol. 2002;29:693–8.CrossRef Higaki Y, Kawamoto K, Kamo T, Horikawa N, Kawashima M, Chren MM. The Japanese version of Skindex-16: a brief quality-of-life measure for patients with skin diseases. Dermatol. 2002;29:693–8.CrossRef
15.
go back to reference Hu L, Bentler PM. Fit indices in covariance structure modeling: sensitivity to underparameterized model misspecification. Psychol Methods. 1998;3:424–53.CrossRef Hu L, Bentler PM. Fit indices in covariance structure modeling: sensitivity to underparameterized model misspecification. Psychol Methods. 1998;3:424–53.CrossRef
16.
go back to reference Hu LT, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Model. 1999;6:1–55.CrossRef Hu LT, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Model. 1999;6:1–55.CrossRef
17.
go back to reference He Z, Lu C, Chren MM, Zhang Z, Li Y, Ni X, et al. Development and psychometric validation of the Chinese version of Skindex-29 and Skindex-16. Health Qual Life Outcomes. 2014;12:190.CrossRefPubMedPubMedCentral He Z, Lu C, Chren MM, Zhang Z, Li Y, Ni X, et al. Development and psychometric validation of the Chinese version of Skindex-29 and Skindex-16. Health Qual Life Outcomes. 2014;12:190.CrossRefPubMedPubMedCentral
18.
go back to reference AlGhamdi KM, AlShammari SA. Arabic version of Skindex-16: translation and cultural adaptation, with assessment of reliability and validity. Int J Dermatol. 2007;46:247–52.CrossRefPubMed AlGhamdi KM, AlShammari SA. Arabic version of Skindex-16: translation and cultural adaptation, with assessment of reliability and validity. Int J Dermatol. 2007;46:247–52.CrossRefPubMed
19.
go back to reference Chua SL, Maurer T, Chren MM. Adaptation of a Runyankore version of Skindex-16 for oral administration in Mbarara. Uganda Int J Dermatol. 2011;50:1249–54. Chua SL, Maurer T, Chren MM. Adaptation of a Runyankore version of Skindex-16 for oral administration in Mbarara. Uganda Int J Dermatol. 2011;50:1249–54.
20.
go back to reference El Fakir S, Baybay H, Bendahhou K, Obtel M, Benchat L, Mernissi FZ, et al. Validation of the Skindex-16 questionnaire in patients with skin diseases in Morocco. J Dermatol Treat. 2012;25:106–9.CrossRef El Fakir S, Baybay H, Bendahhou K, Obtel M, Benchat L, Mernissi FZ, et al. Validation of the Skindex-16 questionnaire in patients with skin diseases in Morocco. J Dermatol Treat. 2012;25:106–9.CrossRef
21.
go back to reference Abolfotouh MA, Al-Khowailed MS, Suliman WE, Al-Turaif DA, Al-Bluwi E, Al-Kahtani HS. Quality of life in patients with skin diseases in central Saudi Arabia. Int J Genl Med. 2012;5:633–42.CrossRef Abolfotouh MA, Al-Khowailed MS, Suliman WE, Al-Turaif DA, Al-Bluwi E, Al-Kahtani HS. Quality of life in patients with skin diseases in central Saudi Arabia. Int J Genl Med. 2012;5:633–42.CrossRef
22.
go back to reference Lundberg L, Johannesson M, Silverdahl M, Hermansson C, Lindberg M. Health-related quality of life in patients with psoriasis and atopic dermatitis measured with SF-36, DLQI and a subjective measure of disease activity. Acta Derm Venereol. 2000;80(6):430–4.CrossRefPubMed Lundberg L, Johannesson M, Silverdahl M, Hermansson C, Lindberg M. Health-related quality of life in patients with psoriasis and atopic dermatitis measured with SF-36, DLQI and a subjective measure of disease activity. Acta Derm Venereol. 2000;80(6):430–4.CrossRefPubMed
23.
go back to reference Zachariae R, Zachariae C, Ibsen HH, Wulf HC, Mortensen JT. Psychological symptoms and quality of life of dermatology outpatients and hospitalized dermatology patients. Acta Derm Venereol. 2004;84:205–12.CrossRefPubMed Zachariae R, Zachariae C, Ibsen HH, Wulf HC, Mortensen JT. Psychological symptoms and quality of life of dermatology outpatients and hospitalized dermatology patients. Acta Derm Venereol. 2004;84:205–12.CrossRefPubMed
24.
go back to reference Coghi S, Bortoletto MC, Sampaio SAP, De Andrade Junior HA, Aoki V. Quality of life is severely compromised in adult patients with atopic dermatitis in Brazil, especially due to mental components. Clinics. 2007;62:235–42.CrossRefPubMed Coghi S, Bortoletto MC, Sampaio SAP, De Andrade Junior HA, Aoki V. Quality of life is severely compromised in adult patients with atopic dermatitis in Brazil, especially due to mental components. Clinics. 2007;62:235–42.CrossRefPubMed
25.
go back to reference Finlay AY, Khan GK. Dermatology life quality index (DLQI)—a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19:210–6.CrossRefPubMed Finlay AY, Khan GK. Dermatology life quality index (DLQI)—a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19:210–6.CrossRefPubMed
26.
go back to reference Kosaraju SKM, Reddy SR, Vadlamani N, Sandhya L, Kalasapati L, Maganti S, et al. Psychological morbidity among dermatological patients in a rural setting. Int J Dermatol. 2015;60:635. Kosaraju SKM, Reddy SR, Vadlamani N, Sandhya L, Kalasapati L, Maganti S, et al. Psychological morbidity among dermatological patients in a rural setting. Int J Dermatol. 2015;60:635.
27.
go back to reference Ghajarzadeh M, Ghiasi M, Kheirkhah S. Associations between skin diseases and quality of life: a comparison of psoriasis, vitiligo, and alopecia areata. Acta Med Iran. 2012;50:511–5.PubMed Ghajarzadeh M, Ghiasi M, Kheirkhah S. Associations between skin diseases and quality of life: a comparison of psoriasis, vitiligo, and alopecia areata. Acta Med Iran. 2012;50:511–5.PubMed
28.
go back to reference Radtke MA, Schafer I, Gajur A, Langenbruch A, Augustin M. Willingness-to-pay and quality of life in patients with vitiligo. Br J Dermatol. 2009;161:134–9.CrossRefPubMed Radtke MA, Schafer I, Gajur A, Langenbruch A, Augustin M. Willingness-to-pay and quality of life in patients with vitiligo. Br J Dermatol. 2009;161:134–9.CrossRefPubMed
29.
go back to reference Poon E, Seed PT, Greaves MW, Kobza-Black A. The extent and nature of disability in different urticarial conditions. Br J Dermatol. 1999;140(4):667–71.CrossRefPubMed Poon E, Seed PT, Greaves MW, Kobza-Black A. The extent and nature of disability in different urticarial conditions. Br J Dermatol. 1999;140(4):667–71.CrossRefPubMed
30.
go back to reference Lasek RJ, Chren MM. Acne vulgaris and the quality of life of adult dermatology patients. Arch Dermatol. 1998;134:454–8.CrossRefPubMed Lasek RJ, Chren MM. Acne vulgaris and the quality of life of adult dermatology patients. Arch Dermatol. 1998;134:454–8.CrossRefPubMed
31.
go back to reference Grob JJ, Revuz J, Ortonne JP, Auguier P, Lorette G. Comparative study of the impact of chronic urticaria, psoriasis, and atopic dermatitis on the QoL. Int J Dermatol. 2005;152:289–95. Grob JJ, Revuz J, Ortonne JP, Auguier P, Lorette G. Comparative study of the impact of chronic urticaria, psoriasis, and atopic dermatitis on the QoL. Int J Dermatol. 2005;152:289–95.
32.
go back to reference Chernyshov PV. Health related quality of life in adult atopic dermatitis and psoriatic patients matched by disease severity. G Ital Dermatol Venereol. 2014;151:37–43.PubMed Chernyshov PV. Health related quality of life in adult atopic dermatitis and psoriatic patients matched by disease severity. G Ital Dermatol Venereol. 2014;151:37–43.PubMed
33.
go back to reference Mayrshofer F, Herti M, Sinkgraven R, Sticherling M, Pfeiffer C, Zillikens D, et al. Significant decrease in quality of life in patients with pemphigus vulgaris, result from the German bullous skin disease (BSD) study group. J Dtsch Dermatol Ges. 2005;3:431–5. Mayrshofer F, Herti M, Sinkgraven R, Sticherling M, Pfeiffer C, Zillikens D, et al. Significant decrease in quality of life in patients with pemphigus vulgaris, result from the German bullous skin disease (BSD) study group. J Dtsch Dermatol Ges. 2005;3:431–5.
34.
go back to reference Paradisi A, Sampogna F, Di Pietro C, Cianchini G, Didora B, Ferri R, et al. Quality-of-life assessment in patients with pemphigus using a minimum set of evaluation tools. J Am Acad Dermatol. 2009;60(2):261–9.CrossRefPubMed Paradisi A, Sampogna F, Di Pietro C, Cianchini G, Didora B, Ferri R, et al. Quality-of-life assessment in patients with pemphigus using a minimum set of evaluation tools. J Am Acad Dermatol. 2009;60(2):261–9.CrossRefPubMed
35.
go back to reference Prinsen CA, Lindeboom R, Sprangers M, Legierse CM, De Korte J. Health-related quality of life assessment in dermatology: interpretation of Skindex-29 scores using patient-based anchors. J Invest Dermatol. 2010;130:1318–22.CrossRefPubMed Prinsen CA, Lindeboom R, Sprangers M, Legierse CM, De Korte J. Health-related quality of life assessment in dermatology: interpretation of Skindex-29 scores using patient-based anchors. J Invest Dermatol. 2010;130:1318–22.CrossRefPubMed
36.
go back to reference Gurel MS, Yanik M, Simsek Z, Kati M, Karaman A. Quality of life instrument for Turkish people with skin diseases. Int J Dermatol. 2005;44:933–8.CrossRefPubMed Gurel MS, Yanik M, Simsek Z, Kati M, Karaman A. Quality of life instrument for Turkish people with skin diseases. Int J Dermatol. 2005;44:933–8.CrossRefPubMed
37.
go back to reference Tabolli S, Pagliarello C, Di Pietro C, Abeni D. Limited role of marital status in the impact of dermatological diseases on quality of life. Eur J Dermatol. 2012;22:672–7.PubMed Tabolli S, Pagliarello C, Di Pietro C, Abeni D. Limited role of marital status in the impact of dermatological diseases on quality of life. Eur J Dermatol. 2012;22:672–7.PubMed
38.
39.
go back to reference Al Robaee AA. Assessment of general health and quality of life in patients with acne using a validated generic questionnaire. Acta Dermatoven Alp Panonica Adriat. 2009;18:157–64. Al Robaee AA. Assessment of general health and quality of life in patients with acne using a validated generic questionnaire. Acta Dermatoven Alp Panonica Adriat. 2009;18:157–64.
40.
go back to reference Leeyaphan C, Wanitphakdeedeche R, Manuskiatti W, Kulthanan K. Measuring melasma patients’ QoL using willingness to pay and time trade-off methods in thai population. BMC Dermatol. 2011;11:6.CrossRef Leeyaphan C, Wanitphakdeedeche R, Manuskiatti W, Kulthanan K. Measuring melasma patients’ QoL using willingness to pay and time trade-off methods in thai population. BMC Dermatol. 2011;11:6.CrossRef
41.
go back to reference Sampogna F, Spagnoli A, Di Pietro C, Pagliarello C, Paradis A, Tabolli S, et al. Field performance of the Skindex-17 quality of life questionnaire: a comparison with the Skindex-29 in a large sample of dermatological outpatients. J Invest Dermatol. 2013;133:104–9.CrossRefPubMed Sampogna F, Spagnoli A, Di Pietro C, Pagliarello C, Paradis A, Tabolli S, et al. Field performance of the Skindex-17 quality of life questionnaire: a comparison with the Skindex-29 in a large sample of dermatological outpatients. J Invest Dermatol. 2013;133:104–9.CrossRefPubMed
42.
go back to reference Al Robaee AA. Assessment of quality of life in Saudi patients with vitiligo in a medical school in Qassim province. Saudi Arabia Saudi Med J. 2007;28:1414–7. Al Robaee AA. Assessment of quality of life in Saudi patients with vitiligo in a medical school in Qassim province. Saudi Arabia Saudi Med J. 2007;28:1414–7.
43.
go back to reference Szepietowski JC, Reich A, Wesolowska-Szepietowska E, Baran E. Quality of life in patients suffering from seborrheic dermatitis: influence of age, gender and educational level. Mycoses. 2009;52:357–63.CrossRefPubMed Szepietowski JC, Reich A, Wesolowska-Szepietowska E, Baran E. Quality of life in patients suffering from seborrheic dermatitis: influence of age, gender and educational level. Mycoses. 2009;52:357–63.CrossRefPubMed
44.
go back to reference Jobanputra R, Bachmann M. The effect of skin diseases on quality of life in patients from different social and ethnic groups in Cape Town. South Africa Int J Dermatol. 2000;39(11):826–31. Jobanputra R, Bachmann M. The effect of skin diseases on quality of life in patients from different social and ethnic groups in Cape Town. South Africa Int J Dermatol. 2000;39(11):826–31.
45.
go back to reference Quandt SA, Schulz MR, Vallejos QM, Feldman SR, Verma A, Fleischer AB, et al. The association of dermatologist-diagnosed and self-reported skin diseases with skin-related quality of life in Latino migrant farm workers. Int J Dermatol. 2008;47:236–41.CrossRefPubMed Quandt SA, Schulz MR, Vallejos QM, Feldman SR, Verma A, Fleischer AB, et al. The association of dermatologist-diagnosed and self-reported skin diseases with skin-related quality of life in Latino migrant farm workers. Int J Dermatol. 2008;47:236–41.CrossRefPubMed
Metadata
Title
Validation of an Egyptian Arabic Version of Skindex-16 and Quality of Life Measurement in Egyptian Patients with Skin Disease
Authors
Nagwa Essa
Sara Awad
Mariam Nashaat
Publication date
01-04-2018
Publisher
Springer US
Published in
International Journal of Behavioral Medicine / Issue 2/2018
Print ISSN: 1070-5503
Electronic ISSN: 1532-7558
DOI
https://doi.org/10.1007/s12529-017-9677-9

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