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International Journal of Behavioral Medicine

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Open Access 01-04-2018

The Epidemiology of Depressive Symptoms and Poor Sleep: Findings from the English Longitudinal Study of Ageing (ELSA)

Authors: Lydia Poole, Marta Jackowska

Published in: International Journal of Behavioral Medicine | Issue 2/2018

Abstract

Purpose

The reasons for the comorbidity between depressed mood and poor sleep are not well understood.

Method

Participants were 5172 adults aged 50 years and older from the English Longitudinal Study of Ageing. Sleep was measured via self-report and depressive symptoms using the Centre for Epidemiological Studies Depression scale.

Results

Greater depressive symptoms and sleep complaints were associated with female sex, non-cohabitation, relative poverty, smoking, infrequent physical activity, infrequent alcohol consumption, higher body mass index (BMI), diagnosis of hypertension, coronary heart disease, diabetes/high blood glucose, pulmonary disease, arthritis, and higher levels of fibrinogen and C-reactive protein (all p < 0.05). At a 4-year follow-up, depressive symptoms and sleep complaints were both predicted by baseline depressive symptoms and sleep complaints, relative poverty, smoking, physical inactivity, BMI, and arthritis (all p < 0.05).

Conclusion

Depressive symptoms and sleep complaints share a range of correlates cross-sectionally and prospectively. These findings highlight the common comorbidity between depressive symptoms and sleep complaints underscoring the need for further research to understand their combined detrimental effect on long-term health and wellbeing.

Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800. https://doi.org/10.1016/S0140-6736(15)60692-4.CrossRefPubMedCentral

McManus S, Bebbington P, Jenkins R, Brugha T, editors. Mental health and wellbeing in England: Adult Psychiatric Morbidity Survey 2014. Leeds: NHS Digital; 2016.

Mezuk B, Eaton WW, Albrecht S, Golden SH. Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care. 2008;31(12):2383–90. https://doi.org/10.2337/dc08-0985.CrossRefPubMedPubMedCentral

Nicholson A, Kuper H, Hemingway H. Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies. Eur Heart J. 2006;27(23):2763–74. https://doi.org/10.1093/eurheartj/ehl338.CrossRefPubMed

Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF. Late-life depression and risk of vascular dementia and Alzheimer’s disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry J Ment Sci. 2013;202(5):329–35. https://doi.org/10.1192/bjp.bp.112.118307.CrossRef

Chida Y, Hamer M, Wardle J, Steptoe A. Do stress-related psychosocial factors contribute to cancer incidence and survival? Nat Clin Pract Oncol. 2008;5(8):466–75. https://doi.org/10.1038/ncponc1134.CrossRefPubMed

Ahn HK, Bae JH, Ahn HY, Hwang IC. Risk of cancer among patients with depressive disorder: a meta-analysis and implications. Psychooncology. 2016;25(12):1393–9. https://doi.org/10.1002/pon.4084.CrossRefPubMed

Benca RM, Obermeyer WH, Thisted RA, Gillin JC. Sleep and psychiatric disorders. A meta-analysis. Arch Gen Psychiatry. 1992;49(8):651–668; discussion 669-670. https://doi.org/10.1001/archpsyc.1992.01820080059010.CrossRefPubMed

Tsuno N, Besset A, Ritchie K. Sleep and depression. J Clin Psychiatry. 2005;66(10):1254–69. https://doi.org/10.4088/JCP.v66n1008.CrossRefPubMed

10.

Benca RM, Peterson MJ. Insomnia and depression. Sleep Med. 2008;9(Suppl 1):S3–9. https://doi.org/10.1016/S1389-9457(08)70010-8. CrossRefPubMed

11.

Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA J Am Med Assoc. 1989;262(11):1479–84. https://doi.org/10.1001/jama.1989.03430110069030.CrossRef

12.

Taylor DJ, Lichstein KL, Durrence HH, Reidel BW, Bush AJ. Epidemiology of insomnia, depression, and anxiety. Sleep. 2005;28(11):1457–64. https://doi.org/10.1093/sleep/28.11.1457.CrossRefPubMed

13.

Riemann D, Voderholzer U. Primary insomnia: a risk factor to develop depression? J Affect Disord. 2003;76(1–3):255–9. https://doi.org/10.1016/S0165-0327(02)00072-1.CrossRefPubMed

14.

Li L, Wu C, Gan Y, Qu X, Lu Z. Insomnia and the risk of depression: a meta-analysis of prospective cohort studies. BMC Psychiatry. 2016;16(1):375. https://doi.org/10.1186/s12888-016-1075-3. CrossRefPubMedPubMedCentral

15.

Baglioni C, Battagliese G, Feige B, Spiegelhalder K, Nissen C, Voderholzer U, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135(1-3):10–9. https://doi.org/10.1016/j.jad.2011.01.011.CrossRefPubMed

16.

Zhai L, Zhang H, Zhang D. Sleep duration and depression among adults: a meta-analysis of prospective studies. Depress Anxiety. 2015;32(9):664–70. https://doi.org/10.1002/da.22386.CrossRefPubMed

17.

Koyanagi A, Garin N, Olaya B, Ayuso-Mateos JL, Chatterji S, Leonardi M, et al. Chronic conditions and sleep problems among adults aged 50 years or over in nine countries: a multi-country study. PLoS One. 2014;9(12):e114742. https://doi.org/10.1371/journal.pone.0114742.CrossRefPubMedPubMedCentral

18.

Itani O, Jike M, Watanabe N, Kaneita Y. Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression. Sleep Med. 2016;25:130–8. https://doi.org/10.1016/j.sleep.2016.08.006. CrossRefPubMed

19.

Skapinakis P, Rai D, Anagnostopoulos F, Harrison S, Araya R, Lewis G. Sleep disturbances and depressive symptoms: an investigation of their longitudinal association in a representative sample of the UK general population. Psychol Med. 2013;43(2):329–39. https://doi.org/10.1017/S0033291712001055.CrossRefPubMed

20.

Steptoe A, Breeze E, Banks J, Nazroo J. Cohort profile: the English longitudinal study of ageing. Int J Epidemiol. 2013;42(6):1640–8. https://doi.org/10.1093/ije/dys168.CrossRefPubMed

21.

Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(3):385–401. https://doi.org/10.1177/014662167700100306.CrossRef

22.

Steffick D. HRS/AHEAD documentation report. Documentation of affective functioning measures in the Health and Retirement Study 2000. http://hrsonline.isr.umich.edu/sitedocs/userg/dr-005.pdf.

23.

Jenkins CD, Stanton BA, Niemcryk SJ, Rose RM. A scale for the estimation of sleep problems in clinical research. J Clin Epidemiol. 1988;41(4):313–21. https://doi.org/10.1016/0895-4356(88)90138-2.CrossRefPubMed

24.

Wu Y, Zhai L, Zhang D. Sleep duration and obesity among adults: a meta-analysis of prospective studies. Sleep Med. 2014;15(12):1456–62. https://doi.org/10.1016/j.sleep.2014.07.018.CrossRefPubMed

25.

Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J. 2011;32(12):1484–92. https://doi.org/10.1093/eurheartj/ehr007.CrossRefPubMed

26.

Lazzarino AI, Hamer M, Stamatakis E, Steptoe A. The combined association of psychological distress and socioeconomic status with all-cause mortality: a national cohort study. JAMA Intern Med. 2013;173(1):22–7. https://doi.org/10.1001/2013.jamainternmed.951.CrossRefPubMed

27.

Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med. 2009;71(2):171–86. https://doi.org/10.1097/PSY.0b013e3181907c1b.CrossRefPubMed

28.

Whooley MA, de Jonge P, Vittinghoff E, Otte C, Moos R, Carney RM, et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA J Am Med Assoc. 2008;300(20):2379–88. https://doi.org/10.1001/jama.2008.711. CrossRef

29.

Pruchno RA, Wilson-Genderson M, Heid AR. Multiple chronic condition combinations and depression in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2016;71(7):910–5. https://doi.org/10.1093/gerona/glw025.CrossRefPubMed

30.

Arber S, Bote M, Meadows R. Gender and socio-economic patterning of self-reported sleep problems in Britain. Soc Sci Med 1982. 2009;68(2):281–9. https://doi.org/10.1016/j.socscimed.2008.10.016.

31.

Jackowska M, Kumari M, Steptoe A. Sleep and biomarkers in the English Longitudinal Study of Ageing: associations with C-reactive protein, fibrinogen, dehydroepiandrosterone sulfate and hemoglobin. Psychoneuroendocrinology. 2013;38(9):1484–93. https://doi.org/10.1016/j.psyneuen.2012.12.015.CrossRefPubMed

32.

Stranges S, Dorn JM, Shipley MJ, Kandala NB, Trevisan M, Miller MA, et al. Correlates of short and long sleep duration: a cross-cultural comparison between the United Kingdom and the United States: the Whitehall II Study and the Western New York Health Study. Am J Epidemiol. 2008;168(12):1353–64. https://doi.org/10.1093/aje/kwn337.CrossRefPubMedPubMedCentral

33.

Sproston K, Mindell J. Health Survery for England: methodology and documentation, vol. 2. Leeds: The Information Centre; 2004.

34.

Stewart R, Besset A, Bebbington P, Brugha T, Lindesay J, Jenkins R, et al. Insomnia comorbidity and impact and hypnotic use by age group in a national survey population aged 16 to 74 years. Sleep. 2006;29(11):1391–7. https://doi.org/10.1093/sleep/29.11.1391.CrossRefPubMed

35.

Schuch F, Vancampfort D, Firth J, Rosenbaum S, Ward P, Reichert T, et al. Physical activity and sedentary behavior in people with major depressive disorder: a systematic review and meta-analysis. J Affect Disord. 2016;210:139–50. https://doi.org/10.1016/j.jad.2016.10.050. CrossRefPubMed

36.

Penninx BWJH. Depression and cardiovascular disease: epidemiological evidence on their linking mechanisms. Neurosci Biobehav Rev. 2016;74(Pt B):277–86. https://doi.org/10.1016/j.neubiorev.2016.07.003. PubMed

37.

Strine TW, Chapman DP. Associations of frequent sleep insufficiency with health-related quality of life and health behaviors. Sleep Med. 2005;6(1):23–7. https://doi.org/10.1016/j.sleep.2004.06.003.CrossRefPubMed

38.

Everson SA, Maty SC, Lynch JW, Kaplan GA. Epidemiologic evidence for the relation between socioeconomic status and depression, obesity, and diabetes. J Psychosom Res. 2002;53(4):891–5. https://doi.org/10.1016/S0022-3999(02)00303-3.CrossRefPubMed

39.

Yan X-Y, Huang S-M, Huang C-Q, W-H W, Qin Y. Marital status and risk for late life depression: a meta-analysis of the published literature. J Int Med Res. 2011;39(4):1142–54. https://doi.org/10.1177/147323001103900402.CrossRefPubMed

40.

Troxel WM, Buysse DJ, Matthews KA, Kravitz HM, Bromberger JT, Sowers MF, et al. Marital/cohabitation status and history in relation to sleep in midlife women. Sleep. 2010;33(7):973–81. https://doi.org/10.1093/sleep/33.7.973.CrossRefPubMedPubMedCentral

41.

Sullivan LE, Fiellin DA, O’Connor PG. The prevalence and impact of alcohol problems in major depression: a systematic review. Am J Med. 2005;118(4):330–41. https://doi.org/10.1016/j.amjmed.2005.01.007.CrossRefPubMed

42.

Magee CA, Iverson DC, Caputi P. Factors associated with short and long sleep. Prev Med. 2009;49(6):461–7. https://doi.org/10.1016/j.ypmed.2009.10.006.CrossRefPubMed

43.

Ferreira MP, Weems MKS. Alcohol consumption by aging adults in the United States: health benefits and detriments. J Am Diet Assoc. 2008;108(10):1668–76. https://doi.org/10.1016/j.jada.2008.07.011.CrossRefPubMed

44.

Haapakoski R, Mathieu J, Ebmeier KP, Alenius H, Kivimäki M. Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder. Brain Behav Immun. 2015;49:206–15. https://doi.org/10.1016/j.bbi.2015.06.001.CrossRefPubMedPubMedCentral

45.

Irwin MR, Olmstead R, Carroll JE. Sleep disturbance, sleep duration, and inflammation: a systematic review and meta-analysis of cohort studies and experimental sleep deprivation. Biol Psychiatry. 2016;80(1):40–52. https://doi.org/10.1016/j.biopsych.2015.05.014.CrossRefPubMed

46.

Cancello R, Clément K. Review article: is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. BJOG Int J Obstet Gynaecol. 2006;113(10):1141–7. https://doi.org/10.1111/j.1471-0528.2006.01004.x.CrossRef

47.

Hamer M, Endrighi R, Poole L. Physical activity, stress reduction and mood: insight into immunological mechanisms. In: Psychoneuroimmunology: Methods and Protocols. New York: Springer; 2012.

48.

Zee PC, Turek FW. Sleep and health: everywhere and in both directions. Arch Intern Med. 2006;166(16):1686–8. https://doi.org/10.1001/archinte.166.16.1686.CrossRefPubMed

49.

Luyster FS, Chasens ER, Wasko MCM, Dunbar-Jacob J. Sleep quality and functional disability in patients with rheumatoid arthritis. J Clin Sleep Med. 2011;7(1):49–55.PubMedPubMedCentral

50.

Allen KD, Renner JB, Devellis B, Helmick CG, Jordan JM. Osteoarthritis and sleep: the Johnston County Osteoarthritis Project. J Rheumatol. 2008;35(6):1102–7.PubMedPubMedCentral

51.

Dickens C, McGowan L, Clark-Carter D, Creed F. Depression in rheumatoid arthritis: a systematic review of the literature with meta-analysis. Psychosom Med. 2002;64(1):52–60. https://doi.org/10.1097/00006842-200201000-00008.CrossRefPubMed

52.

Chapman DP, Perry GS, Strine TW. The vital link between chronic disease and depressive disorders. Prev Chronic Dis 2004;2(1). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323317/. Accessed 17 Jan 2017.

53.

Motivala SJ. Sleep and inflammation: psychoneuroimmunology in the context of cardiovascular disease. Ann Behav Med. 2011;42(2):141–52. https://doi.org/10.1007/s12160-011-9280-2.CrossRefPubMed

54.

Hamer M, Molloy GJ, de Oliveira C, Demakakos P. Persistent depressive symptomatology and inflammation: to what extent do health behaviours and weight control mediate this relationship? Brain Behav Immun. 2009;23(4):413–8. https://doi.org/10.1016/j.bbi.2009.01.005.CrossRefPubMed

55.

Irwin M, Clark C, Kennedy B, Christian Gillin J, Ziegler M. Nocturnal catecholamines and immune function in insomniacs, depressed patients, and control subjects. Brain Behav Immun. 2003;17(5):365–72. https://doi.org/10.1016/S0889-1591(03)00031-X.CrossRefPubMed

56.

Manber R, Edinger JD, Gress JL, San Pedro-Salcedo MG, Kuo TF, Kalista T. Cognitive behavioral therapy for insomnia enhances depression outcome in patients with comorbid major depressive disorder and insomnia. Sleep. 2008;31(4):489–95. https://doi.org/10.1093/sleep/31.4.489.CrossRefPubMedPubMedCentral

57.

Carroll JE, Seeman TE, Olmstead R, Melendez G, Sadakane R, Bootzin R, et al. Improved sleep quality in older adults with insomnia reduces biomarkers of disease risk: pilot results from a randomized controlled comparative efficacy trial. Psychoneuroendocrinology. 2015;55:184–92. https://doi.org/10.1016/j.psyneuen.2015.02.010.CrossRefPubMedPubMedCentral

58.

Jackowska M, Dockray S, Hendrickx H, Steptoe A. Psychosocial factors and sleep efficiency: discrepancies between subjective and objective evaluations of sleep. Psychosom Med. 2011;73(9):810–6. https://doi.org/10.1097/PSY.0b013e3182359e77.CrossRefPubMed

59.

Simpson CF, Boyd CM, Carlson MC, Griswold ME, Guralnik JM, Fried LP. Agreement between self-report of disease diagnoses and medical record validation in disabled older women: factors that modify agreement. J Am Geriatr Soc. 2004;52(1):123–7. https://doi.org/10.1111/j.1532-5415.2004.52021.x.CrossRefPubMed

Title: The Epidemiology of Depressive Symptoms and Poor Sleep: Findings from the English Longitudinal Study of Ageing (ELSA)
Authors: Lydia Poole
Marta Jackowska
Publication date: 01-04-2018
Publisher: Springer US
Published in: International Journal of Behavioral Medicine / Issue 2/2018
Print ISSN: 1070-5503
Electronic ISSN: 1532-7558
DOI: https://doi.org/10.1007/s12529-017-9703-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The Epidemiology of Depressive Symptoms and Poor Sleep: Findings from the English Longitudinal Study of Ageing (ELSA)

Abstract

Purpose

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Method

Results

Conclusion

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