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01-08-2018 | Review Article

Isolated cardiac sarcoidosis: A focused review of an under-recognized entity

Authors: David R. Okada, MD, Paco E. Bravo, MD, Tomas Vita, MD, Vikram Agarwal, MBBS, Michael T. Osborne, MD, Viviany R. Taqueti, MD, MPH, Hicham Skali, MD, MSc, Panithaya Chareonthaitawee, MD, Sharmila Dorbala, MD, MPH, Garrick Stewart, MD, Marcelo Di Carli, MD, Ron Blankstein, MD

Published in: Journal of Nuclear Cardiology | Issue 4/2018

Abstract

There is accumulating evidence for the existence of a phenotype of isolated cardiac sarcoidosis (ICS), or sarcoidosis that only involves the heart. In the absence of biopsy-confirmed cardiac sarcoidosis (CS), existing diagnostic criteria require the presence of extra-cardiac sarcoidosis as an inclusion criterion for the diagnosis of CS. Consequently, in the absence of a positive endomyocardial biopsy, ICS is not diagnosable by current guidelines. Therefore, there is uncertainty regarding the epidemiology, pathobiology, clinical characteristics, prognosis, and optimal treatment of ICS. This review will summarize the available data related to the prevalence and prognosis of ICS and will discuss challenges surrounding the diagnosis and management of this under-recognized entity.

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Title: Isolated cardiac sarcoidosis: A focused review of an under-recognized entity
Authors: David R. Okada, MD
Paco E. Bravo, MD
Tomas Vita, MD
Vikram Agarwal, MBBS
Michael T. Osborne, MD
Viviany R. Taqueti, MD, MPH
Hicham Skali, MD, MSc
Panithaya Chareonthaitawee, MD
Sharmila Dorbala, MD, MPH
Garrick Stewart, MD
Marcelo Di Carli, MD
Ron Blankstein, MD
Publication date: 01-08-2018
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 4/2018
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-016-0658-1

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