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01-04-2012 | Review Article

Quantitative analysis of perfusion studies: Strengths and pitfalls

Authors: Piotr Slomka, PhD, Yuan Xu, PhD, Daniel Berman, MD, Guido Germano, PhD

Published in: Journal of Nuclear Cardiology | Issue 2/2012

Excerpt

Quantitative analysis of myocardial perfusion SPECT (MPS) studies has become a mainstay in nuclear cardiology practice. Software tools developed by several groups are now commercially available and are routinely used. These programs can automatically compute several important clinical parameters, such as amount of hypoperfusion at stress and rest. What is the value of these tools to a nuclear cardiology practitioner or a clinical researcher? How do they compare to visual analysis? What are their limitations? In this review, we look at the standard features of such quantitative tools, compare it with the visual scoring technique, and discuss particular strengths of the quantitative approach. We also highlight several possible challenges in applying quantitative analysis and discuss some recent software developments, which can mitigate these difficulties. …

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Title: Quantitative analysis of perfusion studies: Strengths and pitfalls
Authors: Piotr Slomka, PhD
Yuan Xu, PhD
Daniel Berman, MD
Guido Germano, PhD
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Journal of Nuclear Cardiology / Issue 2/2012
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-011-9509-2

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