Published in:
01-08-2010 | Editorial
Heart rate response during vasodilator stress myocardial perfusion imaging: Mechanisms and implications
Authors:
Fadi G. Hage, MD, Ami E. Iskandrian, MD, MACC
Published in:
Journal of Nuclear Cardiology
|
Issue 4/2010
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Excerpt
Myocardial perfusion imaging (MPI) using adenosine, dipyridamole, or regadenoson (a selective A
2A receptor agonist) is an established method for detecting coronary artery disease (CAD) and risk stratification.
1 In high-risk populations, as in those with diabetes mellitus (DM) or chronic kidney disease, MPI has been shown to be a powerful predictor of risk, but nevertheless, patients with normal myocardial perfusion are at higher risk than those without DM or chronic kidney disease.
2,
3 Thus, there continues to be a need to extract more useful prognostic data from stress MPI especially in high-risk populations. …