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Published in: Journal of Nuclear Cardiology 1/2010

01-02-2010 | Editor's Page

Importance of consideration of radiation doses from cardiac imaging procedures and risks of cancer

Author: George A. Beller, MD

Published in: Journal of Nuclear Cardiology | Issue 1/2010

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Excerpt

In recent years, there has been more attention and publicity to the radiation exposure experienced by patients undergoing cardiac imaging procedures such as computed tomography coronary angiography (CTA) and SPECT and PET perfusion imaging. The risk of radiation-related cancer risk from CT scans performed in the United States has not been adequately appreciated. Recent publications have voiced concern regarding future cancer risks from the many CT scans performed on an annual basis in the United States.1-3 What is surprising and somewhat alarming is that radiation doses from diagnostic CT examinations are higher and more variable than generally quoted.3,4 The issue is not a trivial one since between 1992, the number of CT scans performed in the United States quadrupled. In 2007 alone, 72 million CT scans were performed.5 It was estimated that from this number, 29,000 excess cancers would result causing 15,000 deaths in the next 20 to 30 years. Another study published in the New England Journal of Medicine surveyed 952,420 adults between the ages of 18 and 64 over a 3-year period.2 Of these, 69% (655,613) underwent at least one imaging procedure associated with radiation exposure. CT and nuclear imaging accounted for just 21% of the total number of procedures but 75.4% of the total cumulative effective dose. In this study, a high radiation dose was defined as >20-50 mSv and a very high dose as >50 mSv. High and very high doses were incurred in 18.6 and 1.9 enrollees per 1000 per year, respectively. Cumulative effective doses of radiation increased with advancing age and were higher in women than in men. …
Literature
1.
go back to reference Einstein AJ, Henzlova MY, Rajagopalan S, et al. Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA 2007;298:316-23.CrossRef Einstein AJ, Henzlova MY, Rajagopalan S, et al. Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA 2007;298:316-23.CrossRef
2.
go back to reference Fazel R, Krumholz HM, Wang W, et al. Exposure to low-dose ionizing radiation from medical imaging procedures. N Engl J Med 2009;361:849-57.CrossRefPubMed Fazel R, Krumholz HM, Wang W, et al. Exposure to low-dose ionizing radiation from medical imaging procedures. N Engl J Med 2009;361:849-57.CrossRefPubMed
3.
go back to reference Berrington de Gonzalez A, Mahest M, Kim P-Y, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med 2009;169:2071-7.CrossRefPubMed Berrington de Gonzalez A, Mahest M, Kim P-Y, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med 2009;169:2071-7.CrossRefPubMed
4.
go back to reference Hausleeiter J, Meyer T, Hermann F, et al. Estimated radiation dose associated with cardiac CT angiography. JAMA 2009;301:500-7.CrossRef Hausleeiter J, Meyer T, Hermann F, et al. Estimated radiation dose associated with cardiac CT angiography. JAMA 2009;301:500-7.CrossRef
5.
go back to reference Smith-Bindman R, Lipson J, Marcus R, et al. Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 2009;169:2078-86.CrossRefPubMed Smith-Bindman R, Lipson J, Marcus R, et al. Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 2009;169:2078-86.CrossRefPubMed
7.
go back to reference National Council on Radiation Protection and Measurements. Ionizing radiation exposure of the population of the United States: Recommendations of the National Council on Radiation Protection and Measurements. Report no. 160. Bethesda, MD: NCRP, March 2009. National Council on Radiation Protection and Measurements. Ionizing radiation exposure of the population of the United States: Recommendations of the National Council on Radiation Protection and Measurements. Report no. 160. Bethesda, MD: NCRP, March 2009.
8.
go back to reference Mettler FA Jr, Thomadsen BR, Bhargavan M, et al. Medical radiation exposure in the U.S. in 2006: Preliminary results. Health Phys 2008;95:502-7.CrossRefPubMed Mettler FA Jr, Thomadsen BR, Bhargavan M, et al. Medical radiation exposure in the U.S. in 2006: Preliminary results. Health Phys 2008;95:502-7.CrossRefPubMed
10.
go back to reference Bischoff B, Hein FN, Meyer F, et al. Impact of reduced tube voltage on CT angiogrpaphy and radiation dose: Results of the PROTECTION I Study. J Am Coll Cardiol Imaging 2009;2:940-6. Bischoff B, Hein FN, Meyer F, et al. Impact of reduced tube voltage on CT angiogrpaphy and radiation dose: Results of the PROTECTION I Study. J Am Coll Cardiol Imaging 2009;2:940-6.
11.
go back to reference Raff GL, Chinnaiyan KM, Share DA, et al. Radiation dose from cardiac computed tomography before and after implementation of radiation dose-reduction techniques. JAMA 2009;301:2340-8.CrossRefPubMed Raff GL, Chinnaiyan KM, Share DA, et al. Radiation dose from cardiac computed tomography before and after implementation of radiation dose-reduction techniques. JAMA 2009;301:2340-8.CrossRefPubMed
12.
go back to reference Einstein AJ, Wolff SD, Manheimer ED, et al. Comparison of image quality and radiation dose of coronary computed tomography angiography between conventional helical scanning and a strategy incorporating sequential scanning. Am J Cardiol 2009;104:1343-50.CrossRefPubMed Einstein AJ, Wolff SD, Manheimer ED, et al. Comparison of image quality and radiation dose of coronary computed tomography angiography between conventional helical scanning and a strategy incorporating sequential scanning. Am J Cardiol 2009;104:1343-50.CrossRefPubMed
13.
go back to reference Chang SM, Nabi F, Xu J, Raza U, Mahmarian JJ. Normal stress-only versus standard stress/rest myocardial perfusion imaging: Similar patient mortality with reduced radiation exposure. J Am Coll Cardiol 2010. PMD 19913381 [Epub ahead of print]. Chang SM, Nabi F, Xu J, Raza U, Mahmarian JJ. Normal stress-only versus standard stress/rest myocardial perfusion imaging: Similar patient mortality with reduced radiation exposure. J Am Coll Cardiol 2010. PMD 19913381 [Epub ahead of print].
14.
go back to reference Bourque JM, Holland BH, Watson DD, Beller GA. Achieving an exercise workload of > or + 10 metabolic equivalents predicts a very low risk of inducible ischemia: Does myocardial perfusion imaging have a role. J Am Coll Cardiol 2009;54:538-45.CrossRefPubMed Bourque JM, Holland BH, Watson DD, Beller GA. Achieving an exercise workload of > or + 10 metabolic equivalents predicts a very low risk of inducible ischemia: Does myocardial perfusion imaging have a role. J Am Coll Cardiol 2009;54:538-45.CrossRefPubMed
15.
go back to reference Javadi M, Mahesh M, McBride G, et al. Lowering radiation dose for integrated assessment of coronary morphology and physiology: First experience with step-and-shoot CT angiography in a rubidium 82 PET-CT protocol. J Nucl Cardiol 2008;15:783-90.PubMed Javadi M, Mahesh M, McBride G, et al. Lowering radiation dose for integrated assessment of coronary morphology and physiology: First experience with step-and-shoot CT angiography in a rubidium 82 PET-CT protocol. J Nucl Cardiol 2008;15:783-90.PubMed
16.
go back to reference Redberg RF. Cancer risks and radiation exposure from computed tomographic scans: How can we be sure that the benefits outweigh the risks. Arch Intern Med 2009;169:2049-50.CrossRefPubMed Redberg RF. Cancer risks and radiation exposure from computed tomographic scans: How can we be sure that the benefits outweigh the risks. Arch Intern Med 2009;169:2049-50.CrossRefPubMed
Metadata
Title
Importance of consideration of radiation doses from cardiac imaging procedures and risks of cancer
Author
George A. Beller, MD
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Journal of Nuclear Cardiology / Issue 1/2010
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-009-9189-3

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