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Published in: Advances in Therapy 2/2021

Open Access 01-09-2021 | Mood Disorders | Editorial

Generalised Anxiety Disorder and Depression: Contemporary Treatment Approaches

Authors: Guy M. Goodwin, Dan J. Stein

Published in: Advances in Therapy | Special Issue 2/2021

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Excerpt

Why carry out this review?
Generalised anxiety disorder (GAD) and major depressive disorder (MDD) form part of a large group of prevalent psychiatric disorders, and are frequently comorbid.
These manuscripts describe presentations from a virtual symposium titled “GAD and Depression: Contemporary Treatment Approaches” as part of the Industry Science Exchange sessions that took place as at the European College of Neuropsychopharmacology 33rd Congress in September 2020.
What was learned from the review?
Selective serotonin reuptake inhibitors and serotonin–norepinephrine reuptake inhibitors are considered first-line therapy in patients with GAD, but agents with a different mechanism of action may also be considered in those who do not respond to or tolerate these therapies.
Patients with MDD with symptoms of GAD, also referred to as anxious depression, should be managed with an antidepressant that has anti-anxiety effects.
Greater recognition of anxious depression is needed as this condition is often accompanied by increased suicidality and the need for more robust treatment.
Literature
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go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric; 2013.CrossRef American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric; 2013.CrossRef
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go back to reference Huh J, Goebert D, Takeshita J, Lu BY, Kang M. Treatment of generalized anxiety disorder: a comprehensive review of the literature for psychopharmacologic alternatives to newer antidepressants and benzodiazepines. Prim Care Companion CNS Disord. 2011;13(2):PCC.08r00709. https://doi.org/10.4088/pcc.08r00709blu. Huh J, Goebert D, Takeshita J, Lu BY, Kang M. Treatment of generalized anxiety disorder: a comprehensive review of the literature for psychopharmacologic alternatives to newer antidepressants and benzodiazepines. Prim Care Companion CNS Disord. 2011;13(2):PCC.08r00709. https://​doi.​org/​10.​4088/​pcc.​08r00709blu.
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go back to reference Murray CJ. Quantifying the burden of disease: the technical basis for disability-adjusted life years. Bull World Health Organ. 1994;72(3):429–45.PubMedPubMedCentral Murray CJ. Quantifying the burden of disease: the technical basis for disability-adjusted life years. Bull World Health Organ. 1994;72(3):429–45.PubMedPubMedCentral
Metadata
Title
Generalised Anxiety Disorder and Depression: Contemporary Treatment Approaches
Authors
Guy M. Goodwin
Dan J. Stein
Publication date
01-09-2021
Publisher
Springer Healthcare
Published in
Advances in Therapy / Issue Special Issue 2/2021
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-021-01859-8
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