Skip to main content
Top
Published in: Current Reviews in Musculoskeletal Medicine 3-4/2008

Open Access 01-12-2008

Ganglion cysts of the wrist: pathophysiology, clinical picture, and management

Authors: Warren Gude, Vincent Morelli

Published in: Current Reviews in Musculoskeletal Medicine | Issue 3-4/2008

Login to get access

Abstract

This article reviews what is known about ganglion cyst formation, natural history (50% of cysts will spontaneously resolve), diagnosis, and management of this common malady. Although the exact mechanism of cyst formation is unknown, most current theories hold that extra-articular mucin “droplets” coalesce to form the main body of the tumor. Only subsequently are the “cyst wall” and pedicle (connecting the cyst to a nearby synovial joint) formed. Treatment options include watchful waiting, nonoperative aspiration/injection, and surgical removal. Although treatment is often unnecessary, many patients seeking consultation desire some form of definitive treatment. Cyst aspiration/injection is fraught with a high incidence of recurrence. Surgery generally results in lower rates of recurrence, but a higher incidence of complications. All current treatment options are suboptimal.
Literature
1.
go back to reference Angelides AC, Wallace PF. The dorsal ganglion of the wrist: its pathogenesis, gross and microscopic anatomy, and surgical treatment. J Hand Surg. 1976;1(3):228–35. Angelides AC, Wallace PF. The dorsal ganglion of the wrist: its pathogenesis, gross and microscopic anatomy, and surgical treatment. J Hand Surg. 1976;1(3):228–35.
2.
go back to reference Clay NR, Clement DA. The treatment of dorsal wrist ganglia by radical excision. J Hand Surg. 1988;13(2):187–91.CrossRef Clay NR, Clement DA. The treatment of dorsal wrist ganglia by radical excision. J Hand Surg. 1988;13(2):187–91.CrossRef
3.
go back to reference Greendyke SD, Wilson M, Shepler TR. Anterior wrist ganglia from the scaphotrapezial joint. J Hand Surg. 1992;17(3):487–90.CrossRef Greendyke SD, Wilson M, Shepler TR. Anterior wrist ganglia from the scaphotrapezial joint. J Hand Surg. 1992;17(3):487–90.CrossRef
4.
go back to reference Thornburg LE. Ganglions of the hand and wrist. J Am Acad Orthop Surg. 1999;7(4):231–38.PubMed Thornburg LE. Ganglions of the hand and wrist. J Am Acad Orthop Surg. 1999;7(4):231–38.PubMed
5.
go back to reference Tophoj K, Henriques U. Ganglion of the wrist—a structure developed from the joint. Acta Orthop Scand. 1971;42(3):244–50.PubMed Tophoj K, Henriques U. Ganglion of the wrist—a structure developed from the joint. Acta Orthop Scand. 1971;42(3):244–50.PubMed
6.
go back to reference Andren L, Eiken O. Arthrographic studies of wrist ganglions. J Bone Joint Surg Am. 1971;53(2):299–302.PubMed Andren L, Eiken O. Arthrographic studies of wrist ganglions. J Bone Joint Surg Am. 1971;53(2):299–302.PubMed
7.
go back to reference McEvedy BV. The simple ganglion. A review of modes of treatment and an explanation of the frequent failures of surgery. Lancet. 1954;266(6803):135–6.PubMedCrossRef McEvedy BV. The simple ganglion. A review of modes of treatment and an explanation of the frequent failures of surgery. Lancet. 1954;266(6803):135–6.PubMedCrossRef
8.
go back to reference Osterman AL, Raphael J. Arthroscopic treatment of dorsal ganglion of the wrist. Hand Clin. 1995;11:7–12.PubMed Osterman AL, Raphael J. Arthroscopic treatment of dorsal ganglion of the wrist. Hand Clin. 1995;11:7–12.PubMed
9.
go back to reference Psalia JV, Mansel RE. The surface ultrastructure of ganglia. J Bone Joint Surg Br. 1978;60-B(2):228–33. Psalia JV, Mansel RE. The surface ultrastructure of ganglia. J Bone Joint Surg Br. 1978;60-B(2):228–33.
10.
go back to reference Loder RT, Robinson JH, Jackson WT, Allen DJ. A surface ultrastructure study of ganglia and digital mucous cysts. J Hand Surg. 1988;13(5):758–62. Loder RT, Robinson JH, Jackson WT, Allen DJ. A surface ultrastructure study of ganglia and digital mucous cysts. J Hand Surg. 1988;13(5):758–62.
11.
go back to reference Breidahl WH, Adler RS. Ultrasound-guided injection of ganglia with corticosteroids. Skeletal Radiol. 1996;25(7):635–8.PubMedCrossRef Breidahl WH, Adler RS. Ultrasound-guided injection of ganglia with corticosteroids. Skeletal Radiol. 1996;25(7):635–8.PubMedCrossRef
12.
go back to reference Nahra ME, Bucchieri JS. Ganglion cysts and other tumor related conditions of the hand and wrist. Hand Clin. 2004;20(3):249–60.PubMedCrossRef Nahra ME, Bucchieri JS. Ganglion cysts and other tumor related conditions of the hand and wrist. Hand Clin. 2004;20(3):249–60.PubMedCrossRef
13.
go back to reference Duncan KH, Lewis RC. Scapholunate instability following ganglion cyst excision: a case report. Clin Orthop Relat Res. 1988;228:250–3.PubMed Duncan KH, Lewis RC. Scapholunate instability following ganglion cyst excision: a case report. Clin Orthop Relat Res. 1988;228:250–3.PubMed
14.
go back to reference Jagers M, Akkerhuis P, Van Der Heijden M, Brink PRG. Hyaluronidase versus surgical excision of ganglia: a prospective, randomized clinical trial. J Hand Surg. 2002;27(3):256–8. Jagers M, Akkerhuis P, Van Der Heijden M, Brink PRG. Hyaluronidase versus surgical excision of ganglia: a prospective, randomized clinical trial. J Hand Surg. 2002;27(3):256–8.
15.
go back to reference Nishikawa S, Toh S, Miura K, Arai K, Irie T. Arthroscopic diagnosis and treatment of dorsal wrist ganglion. J Hand Surg. 2001;26(6):547–9. Nishikawa S, Toh S, Miura K, Arai K, Irie T. Arthroscopic diagnosis and treatment of dorsal wrist ganglion. J Hand Surg. 2001;26(6):547–9.
16.
go back to reference Derbyshire RC. Observations on the treatment of ganglia with a report on hydrocortisone. Am J Surg. 1966;112(5):635–6.PubMedCrossRef Derbyshire RC. Observations on the treatment of ganglia with a report on hydrocortisone. Am J Surg. 1966;112(5):635–6.PubMedCrossRef
17.
go back to reference Paul AS, Sochart DH. Improving the results of ganglion aspiration by the use of hyaluronidase. J Hand Surg. 1997;22(2):219–21. Paul AS, Sochart DH. Improving the results of ganglion aspiration by the use of hyaluronidase. J Hand Surg. 1997;22(2):219–21.
18.
go back to reference Westbrook AP, Stephen AB, Oni J, Davis TR. Ganglia: the patient’s perception. J Hand Surg. 2000;25(6):566–7. Westbrook AP, Stephen AB, Oni J, Davis TR. Ganglia: the patient’s perception. J Hand Surg. 2000;25(6):566–7.
19.
go back to reference Rizzo M, Berger R, Steinmann S, Bishop A. Arthroscopic resection in the management of dorsal wrist ganglions: results with a minimum two-year follow-up period. J Hand Surg. 2004;29(1):59–62.CrossRef Rizzo M, Berger R, Steinmann S, Bishop A. Arthroscopic resection in the management of dorsal wrist ganglions: results with a minimum two-year follow-up period. J Hand Surg. 2004;29(1):59–62.CrossRef
20.
go back to reference Jacobs LGH, Govaers KHM. The volar wrist ganglion: just a simple cyst? J Hand Surg. 1990;15(3):342–6. Jacobs LGH, Govaers KHM. The volar wrist ganglion: just a simple cyst? J Hand Surg. 1990;15(3):342–6.
21.
go back to reference Nelson CL, Sawmiller S. Phalen GS: ganglions of the wrist and hand. J Bone Joint Surg Am. 1972;54(7):1459–64.PubMed Nelson CL, Sawmiller S. Phalen GS: ganglions of the wrist and hand. J Bone Joint Surg Am. 1972;54(7):1459–64.PubMed
22.
go back to reference Varley GW, Neidoff M, Davis TRC, Clay NR. Conservative management of wrist ganglia: aspiration versus steroid infiltration. J Hand Surg. 1997;22(5):636–7. Varley GW, Neidoff M, Davis TRC, Clay NR. Conservative management of wrist ganglia: aspiration versus steroid infiltration. J Hand Surg. 1997;22(5):636–7.
23.
go back to reference Wright TW, Cooney WP, Ilstrup M. Anterior wrist ganglion. J Hand Surg. 1994;19(6):954–8.CrossRef Wright TW, Cooney WP, Ilstrup M. Anterior wrist ganglion. J Hand Surg. 1994;19(6):954–8.CrossRef
24.
go back to reference Richman JA, Gelberman RH, Engber WD, Salamon PB, Bean DJ. Ganglions of the wrist and digits and results of treatment by aspiration and cyst wall puncture. J Hand Surg. 1987;12(6):1041–3. Richman JA, Gelberman RH, Engber WD, Salamon PB, Bean DJ. Ganglions of the wrist and digits and results of treatment by aspiration and cyst wall puncture. J Hand Surg. 1987;12(6):1041–3.
25.
go back to reference Korman J, Pearl R, Hentz VR. Efficacy of immobilization following aspiration of carpal and digital ganglions. J Hand Surg. 1992;17(6):1097–9.CrossRef Korman J, Pearl R, Hentz VR. Efficacy of immobilization following aspiration of carpal and digital ganglions. J Hand Surg. 1992;17(6):1097–9.CrossRef
26.
go back to reference Bruner JM. Treatment of “sesamoid” synovial ganglia of the hand by needle rupture. J Bone Joint Surg Am. 1963;45:1689–90.PubMed Bruner JM. Treatment of “sesamoid” synovial ganglia of the hand by needle rupture. J Bone Joint Surg Am. 1963;45:1689–90.PubMed
27.
go back to reference Dias J, Buch K. Palmar wrist ganglion: does intervention improve outcome? J Hand Surg. 2003;28(2):172–6. Dias J, Buch K. Palmar wrist ganglion: does intervention improve outcome? J Hand Surg. 2003;28(2):172–6.
28.
go back to reference Stephen AB, Lyons AR, Davis TRC. A prospective study of two conservative treatments for ganglia of the wrist. J Hand Surg. 1999;24(1):104–5. Stephen AB, Lyons AR, Davis TRC. A prospective study of two conservative treatments for ganglia of the wrist. J Hand Surg. 1999;24(1):104–5.
29.
go back to reference Mackie IG, Howard CB, Wilkens P. The dangers of sclerotherapy in the treatment of ganglia. J Hand Surg. 1984;9(2):181–4. Mackie IG, Howard CB, Wilkens P. The dangers of sclerotherapy in the treatment of ganglia. J Hand Surg. 1984;9(2):181–4.
30.
go back to reference Gang RK, Makhlouf S. Treatment of ganglia by a thread technique. J Hand Surg. 1988;13(2):184–6. Gang RK, Makhlouf S. Treatment of ganglia by a thread technique. J Hand Surg. 1988;13(2):184–6.
31.
go back to reference Oni JA. Letter to the editor. J Hand Surg. 1993;18B:410. Oni JA. Letter to the editor. J Hand Surg. 1993;18B:410.
32.
go back to reference Zubowicz VN, Ischii CH. Management of ganglion cysts of the hand by simple aspiration. J Hand Surg. 1987;12(4):618–20. Zubowicz VN, Ischii CH. Management of ganglion cysts of the hand by simple aspiration. J Hand Surg. 1987;12(4):618–20.
33.
go back to reference Luchetti R, Badia A, Alfarano M, Orbay J, Indriago I, Mustapha B. Arthroscopic resection of dorsal wrist ganglia and treatment of recurrences. J Hand Surg. 2000;25(1):38–40. Luchetti R, Badia A, Alfarano M, Orbay J, Indriago I, Mustapha B. Arthroscopic resection of dorsal wrist ganglia and treatment of recurrences. J Hand Surg. 2000;25(1):38–40.
34.
go back to reference Crawford GP, Taleisnik J. Rotary subluxation of the scaphoid after excision of dorsal carpal ganglion and wrist manipulation: a case report. J Hand Surg. 1983;8(6):921–5. Crawford GP, Taleisnik J. Rotary subluxation of the scaphoid after excision of dorsal carpal ganglion and wrist manipulation: a case report. J Hand Surg. 1983;8(6):921–5.
35.
go back to reference Watson HK, Rogers WD, Ashmead DIV. Re-evaluation of the cause of the wrist ganglion. J Hand Surg. 1989;14(5):812–7.CrossRef Watson HK, Rogers WD, Ashmead DIV. Re-evaluation of the cause of the wrist ganglion. J Hand Surg. 1989;14(5):812–7.CrossRef
Metadata
Title
Ganglion cysts of the wrist: pathophysiology, clinical picture, and management
Authors
Warren Gude
Vincent Morelli
Publication date
01-12-2008
Publisher
Humana Press Inc
Published in
Current Reviews in Musculoskeletal Medicine / Issue 3-4/2008
Electronic ISSN: 1935-9748
DOI
https://doi.org/10.1007/s12178-008-9033-4

Other articles of this Issue 3-4/2008

Current Reviews in Musculoskeletal Medicine 3-4/2008 Go to the issue

OriginalPaper

Coccydynia