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Published in: Current Reviews in Musculoskeletal Medicine 3-4/2008

Open Access 01-12-2008

Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections

Authors: Bradly S. Goodman, Lyle W. F. Posecion, Srinivas Mallempati, Matt Bayazitoglu

Published in: Current Reviews in Musculoskeletal Medicine | Issue 3-4/2008

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Abstract

Lumbar interlaminar and transforaminal epidural injections are used in the treatment of lumbar radicular pain and other lumbar spinal pain syndromes. Complications from these procedures arise from needle placement and the administration of medication. Potential risks include infection, hematoma, intravascular injection of medication, direct nerve trauma, subdural injection of medication, air embolism, disc entry, urinary retention, radiation exposure, and hypersensitivity reactions. The objective of this article is to review the complications of lumbar interlaminar and transforaminal epidural injections and discuss the potential pitfalls related to these procedures. We performed a comprehensive literature review through a Medline search for relevant case reports, clinical trials, and review articles. Complications from lumbar epidural injections are extremely rare. Most if not all complications can be avoided by careful technique with accurate needle placement, sterile precautions, and a thorough understanding of the relevant anatomy and contrast patterns on fluoroscopic imaging.
Literature
1.
go back to reference Boswell MV, Trescott AM, Datta S, American Society of Interventional Pain Physicians, et al. Interventional techniques: evidence-based practice guidelines in the management of chronic spinal pain. Pain Physician. 2007;10:7–111.PubMed Boswell MV, Trescott AM, Datta S, American Society of Interventional Pain Physicians, et al. Interventional techniques: evidence-based practice guidelines in the management of chronic spinal pain. Pain Physician. 2007;10:7–111.PubMed
2.
go back to reference Lutz GE, Vad B, Wisneski RJ. Fluoroscopic transforaminal lumbar epidural steroids: an outcome study. Arch Phys Med Rehabil. 1998;79:1362–6.PubMedCrossRef Lutz GE, Vad B, Wisneski RJ. Fluoroscopic transforaminal lumbar epidural steroids: an outcome study. Arch Phys Med Rehabil. 1998;79:1362–6.PubMedCrossRef
3.
go back to reference Vad V, Bhat A, Lutz G. Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study. Spine. 2002;27:11–6.PubMedCrossRef Vad V, Bhat A, Lutz G. Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study. Spine. 2002;27:11–6.PubMedCrossRef
4.
go back to reference Riew KD, Yin Y, Gilula L, et al. The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Am. 2000;82A:1589–93. Riew KD, Yin Y, Gilula L, et al. The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Am. 2000;82A:1589–93.
5.
go back to reference Westbrook JL, Renowden SA, Carrie LE. Study of the anatomy of the extradural region using magnetic resonance imaging. Br J Anaesth. 1993;71:495–8.PubMedCrossRef Westbrook JL, Renowden SA, Carrie LE. Study of the anatomy of the extradural region using magnetic resonance imaging. Br J Anaesth. 1993;71:495–8.PubMedCrossRef
6.
go back to reference Hogan QH. Lumbar epidural anatomy. A new look by cryomicrotome section. Anesthesiology. 1991;75:767–75.PubMedCrossRef Hogan QH. Lumbar epidural anatomy. A new look by cryomicrotome section. Anesthesiology. 1991;75:767–75.PubMedCrossRef
7.
go back to reference Hogan QH. Epidural anatomy examined by cryomicrotome section. Influence of age, vertebral level, and disease. Reg Anesth. 1996;21:395–406.PubMed Hogan QH. Epidural anatomy examined by cryomicrotome section. Influence of age, vertebral level, and disease. Reg Anesth. 1996;21:395–406.PubMed
8.
go back to reference Gilchrist RV, Slipman CW, Bhagia SM. Anatomy of the Intervertebral Foramen. Pain Physician. 2002;5:372–8.PubMed Gilchrist RV, Slipman CW, Bhagia SM. Anatomy of the Intervertebral Foramen. Pain Physician. 2002;5:372–8.PubMed
9.
go back to reference Bogduk N. Clinical anatomy of the lumbar spine and sacrum. 4th ed. London: Churchill Livingstone; 2005. Bogduk N. Clinical anatomy of the lumbar spine and sacrum. 4th ed. London: Churchill Livingstone; 2005.
10.
go back to reference Mathis JM. Image-guided spine interventions. New York: Springer-Verlag; 2004. Mathis JM. Image-guided spine interventions. New York: Springer-Verlag; 2004.
11.
go back to reference Krauss WE. Vascular anatomy of the spinal cord. Neurosurg Clin N Am. 1999;16:333–45. Krauss WE. Vascular anatomy of the spinal cord. Neurosurg Clin N Am. 1999;16:333–45.
12.
go back to reference Houten JK, Errico TJ. Paraplegia after lumbosacral nerve root block: report of three cases. Spine J. 2002;2:70–5.PubMedCrossRef Houten JK, Errico TJ. Paraplegia after lumbosacral nerve root block: report of three cases. Spine J. 2002;2:70–5.PubMedCrossRef
13.
go back to reference Conners J, Wojack J. Interventional neuroradiology: strategies and practical techniques. Philadelphia: WB Saunders Company; 1999. Conners J, Wojack J. Interventional neuroradiology: strategies and practical techniques. Philadelphia: WB Saunders Company; 1999.
14.
go back to reference Boll DT, Bulow H, Blackham KA, et al. MDCT angiography of the spinal vasculature and the artery of Adamkiewicz. AJR Am J Roentgenol. 2006;187:1054–60.PubMedCrossRef Boll DT, Bulow H, Blackham KA, et al. MDCT angiography of the spinal vasculature and the artery of Adamkiewicz. AJR Am J Roentgenol. 2006;187:1054–60.PubMedCrossRef
15.
16.
go back to reference Tveten L. Spinal cord vascularity. Acta Radiol Diagn (Stockh). 1976;1F:1–16. Tveten L. Spinal cord vascularity. Acta Radiol Diagn (Stockh). 1976;1F:1–16.
17.
go back to reference Botwin KP, Natalicchio J, Hanna A. Fluoroscopic guided lumbar interlaminar epidural injections: a prospective evaluation of epidurography contrast patterns and anatomical review of the epidural space. Pain Physician. 2004;7:77–80.PubMed Botwin KP, Natalicchio J, Hanna A. Fluoroscopic guided lumbar interlaminar epidural injections: a prospective evaluation of epidurography contrast patterns and anatomical review of the epidural space. Pain Physician. 2004;7:77–80.PubMed
18.
go back to reference Bogduk N. Practice guidelines for spinal diagnostic and treatment procedures. ISIS. 1st ed. San Francisco: International Spine Intervention Society; 2004. Bogduk N. Practice guidelines for spinal diagnostic and treatment procedures. ISIS. 1st ed. San Francisco: International Spine Intervention Society; 2004.
19.
go back to reference Jasper JF. Lumbar retrodiscal transforaminal injection. Pain Physician. 2007;10:501–10.PubMed Jasper JF. Lumbar retrodiscal transforaminal injection. Pain Physician. 2007;10:501–10.PubMed
20.
go back to reference Botwin KP, Gruber RD, Bouchlas CG, et al. Complications of fluoroscopically guided transforaminal lumbar epidural injections. Arch Phys Med Rehabil. 2000;81:1045–50.PubMedCrossRef Botwin KP, Gruber RD, Bouchlas CG, et al. Complications of fluoroscopically guided transforaminal lumbar epidural injections. Arch Phys Med Rehabil. 2000;81:1045–50.PubMedCrossRef
21.
go back to reference Huston CW, Slipman CW, Garmin C. Complications and side effects of cervical and lumbosacral selective nerve root injections. Arch Phys Med Rehabil. 2005;86:277–83.PubMedCrossRef Huston CW, Slipman CW, Garmin C. Complications and side effects of cervical and lumbosacral selective nerve root injections. Arch Phys Med Rehabil. 2005;86:277–83.PubMedCrossRef
22.
go back to reference Windsor RE, Storm S, Sugar R. Prevention and management of complications from common spinal injections. Pain Physician. 2003;6:473–83.PubMed Windsor RE, Storm S, Sugar R. Prevention and management of complications from common spinal injections. Pain Physician. 2003;6:473–83.PubMed
23.
go back to reference Hooten WM, Kinney MO, Huntoon MA. Epidural abscess and meningitis after epidural corticosteroid injection. Mayo Clin Proc. 2004;79:682–6.PubMed Hooten WM, Kinney MO, Huntoon MA. Epidural abscess and meningitis after epidural corticosteroid injection. Mayo Clin Proc. 2004;79:682–6.PubMed
24.
go back to reference Gutknecht DR. Chemical meningitis following epidural injections of corticosteroids. Am J Med. 1987;82:570.PubMedCrossRef Gutknecht DR. Chemical meningitis following epidural injections of corticosteroids. Am J Med. 1987;82:570.PubMedCrossRef
25.
go back to reference Kabbara A, Rosenberg SK, Untal C. Methicillin-resistant Staphylococcus aureus epidural abscess after transforaminal epidural steroid injection. Pain Physician. 2004;7:269–72.PubMed Kabbara A, Rosenberg SK, Untal C. Methicillin-resistant Staphylococcus aureus epidural abscess after transforaminal epidural steroid injection. Pain Physician. 2004;7:269–72.PubMed
26.
go back to reference Abram SE, O’Connor TC. Complications associated with epidural steroid injections. Reg Anesth. 1996;21:149–62.PubMed Abram SE, O’Connor TC. Complications associated with epidural steroid injections. Reg Anesth. 1996;21:149–62.PubMed
27.
go back to reference Tham EJ, Stoodley MA, Macintyre PE, et al. Back pain following postoperative epidural analgesia: An indicator of possible infection. Anesth Intensive Care. 1997;25:297–301. Tham EJ, Stoodley MA, Macintyre PE, et al. Back pain following postoperative epidural analgesia: An indicator of possible infection. Anesth Intensive Care. 1997;25:297–301.
28.
go back to reference Yue WM, Tan SB. Distant skip level discitis and vertebral osteomyelitis after caudal epidural injection: a case report of a rare complication of epidural injections. Spine. 2003;28:E209–11.PubMedCrossRef Yue WM, Tan SB. Distant skip level discitis and vertebral osteomyelitis after caudal epidural injection: a case report of a rare complication of epidural injections. Spine. 2003;28:E209–11.PubMedCrossRef
29.
go back to reference Hooten WM, Mizerak A, Carns PE. Discitis after lumbar epidural corticosteroid injection: a case report and analysis of the case report literature. Pain Med. 2006;7:46–51.PubMedCrossRef Hooten WM, Mizerak A, Carns PE. Discitis after lumbar epidural corticosteroid injection: a case report and analysis of the case report literature. Pain Med. 2006;7:46–51.PubMedCrossRef
30.
go back to reference Rigamonti D, Liem L, Sampath P, et al. Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol. 1999;52:189–96.PubMedCrossRef Rigamonti D, Liem L, Sampath P, et al. Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol. 1999;52:189–96.PubMedCrossRef
31.
go back to reference Landefeld CS, Beyth RJ. Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am J Med. 1993;95:315–28.PubMedCrossRef Landefeld CS, Beyth RJ. Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am J Med. 1993;95:315–28.PubMedCrossRef
32.
go back to reference Layton KF, Kallmes DF, Horlocker TT. Recommendations for anticoagulated patients undergoing image-guided spinal procedures. AJNR Am J Neuroradiol. 2006;27:468–70.PubMed Layton KF, Kallmes DF, Horlocker TT. Recommendations for anticoagulated patients undergoing image-guided spinal procedures. AJNR Am J Neuroradiol. 2006;27:468–70.PubMed
33.
go back to reference Stafford-Smith M. Impaired haemostasis and regional anaesthesia. Can J Anaesth. 1996;43:R129–41.PubMed Stafford-Smith M. Impaired haemostasis and regional anaesthesia. Can J Anaesth. 1996;43:R129–41.PubMed
34.
go back to reference Horlocker TT, Wedel DJ, Benzon H, et al. Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA Consensus Conference on Neuraxial Anesthesia and Anticoagulation). Reg Anesth Pain Med. 2003;28:172–97.PubMedCrossRef Horlocker TT, Wedel DJ, Benzon H, et al. Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA Consensus Conference on Neuraxial Anesthesia and Anticoagulation). Reg Anesth Pain Med. 2003;28:172–97.PubMedCrossRef
35.
go back to reference Horlocker TT, Bajwa ZH, Ashraf Z, et al. Risk assessment of hemorrhagic complications associated with nonsteroidal anti-inflammatory medications in ambulatory pain clinic patients undergoing epidural steroid injection. Anesth Analg. 2002;95:1691–7.PubMedCrossRef Horlocker TT, Bajwa ZH, Ashraf Z, et al. Risk assessment of hemorrhagic complications associated with nonsteroidal anti-inflammatory medications in ambulatory pain clinic patients undergoing epidural steroid injection. Anesth Analg. 2002;95:1691–7.PubMedCrossRef
36.
go back to reference Stoll A, Sanchez M. Epidural hematoma after epidural block: implications for its use in pain management. Surg Neurol. 2002;57:235–40.PubMedCrossRef Stoll A, Sanchez M. Epidural hematoma after epidural block: implications for its use in pain management. Surg Neurol. 2002;57:235–40.PubMedCrossRef
37.
go back to reference Lawton MT, Porter RW, Heiserman JE. Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome. J Neurosurg. 1995;83:1–7.PubMedCrossRef Lawton MT, Porter RW, Heiserman JE. Surgical management of spinal epidural hematoma: relationship between surgical timing and neurological outcome. J Neurosurg. 1995;83:1–7.PubMedCrossRef
38.
go back to reference Furman M, Giovanniello M, O’Brien E. Incidence of intravascular penetration in transforaminal lumbosacral epidural steroid injections. Spine. 2000;25:2628–32.PubMedCrossRef Furman M, Giovanniello M, O’Brien E. Incidence of intravascular penetration in transforaminal lumbosacral epidural steroid injections. Spine. 2000;25:2628–32.PubMedCrossRef
39.
go back to reference Carpenter M. Blood supply of the central nervous system. In: Satterfield T, editor. Core text of neuroanatomy. 4th ed. Baltimore: Williams & Wilkins; 1991. Carpenter M. Blood supply of the central nervous system. In: Satterfield T, editor. Core text of neuroanatomy. 4th ed. Baltimore: Williams & Wilkins; 1991.
40.
go back to reference Sullivan WJ, Willick SE, Chira-Adisai W. Incidence of intravascular uptake in lumbar spinal injection procedures. Spine. 2000;25:481–6.PubMedCrossRef Sullivan WJ, Willick SE, Chira-Adisai W. Incidence of intravascular uptake in lumbar spinal injection procedures. Spine. 2000;25:481–6.PubMedCrossRef
41.
go back to reference Goodman BS, Lincoln CE, Deshpande KK. Incidence of intravascular uptake during fluoroscopically guided lumbar disc injections: a prospective observational study. Pain Physician. 2005;8:263–6.PubMed Goodman BS, Lincoln CE, Deshpande KK. Incidence of intravascular uptake during fluoroscopically guided lumbar disc injections: a prospective observational study. Pain Physician. 2005;8:263–6.PubMed
42.
go back to reference Mulroy MF. Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventative measures. Reg Anesth Pain Med. 2002;27:556–61.PubMedCrossRef Mulroy MF. Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventative measures. Reg Anesth Pain Med. 2002;27:556–61.PubMedCrossRef
43.
go back to reference Dreyfuss P, Halbrook B, Pauza K. Efficacy and validity of radiofrequency neurotomy for chronic lumbar zygapophysial joint pain. Spine. 2000;25:1270–7.PubMedCrossRef Dreyfuss P, Halbrook B, Pauza K. Efficacy and validity of radiofrequency neurotomy for chronic lumbar zygapophysial joint pain. Spine. 2000;25:1270–7.PubMedCrossRef
44.
go back to reference Huntoon MA, Martin DP. Paralysis after transforaminal epidural injection and previous spinal surgery. Reg Anesth Pain Med. 2004;29:494–5.PubMedCrossRef Huntoon MA, Martin DP. Paralysis after transforaminal epidural injection and previous spinal surgery. Reg Anesth Pain Med. 2004;29:494–5.PubMedCrossRef
45.
go back to reference Derby R, Lee SH, Date ES, et al. Size and aggregation of corticosteroids used for epidural injections. Pain Med. 2008;9:227–34.PubMedCrossRef Derby R, Lee SH, Date ES, et al. Size and aggregation of corticosteroids used for epidural injections. Pain Med. 2008;9:227–34.PubMedCrossRef
46.
go back to reference Dreyfuss P, Baker R, Bogduk N. Comparative effectiveness of cervical transforaminal injections with particulate and nonparticulate corticosteroid preparations for cervical radicular pain. Pain Med. 2006;7:237–42.PubMedCrossRef Dreyfuss P, Baker R, Bogduk N. Comparative effectiveness of cervical transforaminal injections with particulate and nonparticulate corticosteroid preparations for cervical radicular pain. Pain Med. 2006;7:237–42.PubMedCrossRef
47.
go back to reference Tiso RL, Cutler T, Catania JA, et al. Adverse central nervous system sequelae after selective transforaminal block: the role of corticosteroids. Spine J. 2004;4:468–74.PubMedCrossRef Tiso RL, Cutler T, Catania JA, et al. Adverse central nervous system sequelae after selective transforaminal block: the role of corticosteroids. Spine J. 2004;4:468–74.PubMedCrossRef
48.
go back to reference Goodman BS, Bayazitoglu M, Mallempati S, et al. Dural puncture and subdural injection: a complication of lumbar transforaminal epidural injections. Pain Physician. 2007;10:697–705.PubMed Goodman BS, Bayazitoglu M, Mallempati S, et al. Dural puncture and subdural injection: a complication of lumbar transforaminal epidural injections. Pain Physician. 2007;10:697–705.PubMed
49.
50.
go back to reference Hodgson PS, Neal JM, Pollock JE, et al. The neurotoxicity of drugs given intrathecally (spinal). Anesth Analg. 1999;88:797–809.PubMedCrossRef Hodgson PS, Neal JM, Pollock JE, et al. The neurotoxicity of drugs given intrathecally (spinal). Anesth Analg. 1999;88:797–809.PubMedCrossRef
51.
go back to reference Horlocker TT, McGregor DG, Matsuhige DK, et al. A retrospective review of 4767 consecutive spinal anesthetics: central nervous system complications. Perioperative Outcomes Group. Anesth Analg. 1997;84:578–84.PubMedCrossRef Horlocker TT, McGregor DG, Matsuhige DK, et al. A retrospective review of 4767 consecutive spinal anesthetics: central nervous system complications. Perioperative Outcomes Group. Anesth Analg. 1997;84:578–84.PubMedCrossRef
52.
go back to reference Collier CB. Accidental subdural injection during attempted lumbar epidural block may present as a failed or inadequate block: radiographic evidence. Reg Anesth Pain Med. 2004;29:45–51.PubMedCrossRef Collier CB. Accidental subdural injection during attempted lumbar epidural block may present as a failed or inadequate block: radiographic evidence. Reg Anesth Pain Med. 2004;29:45–51.PubMedCrossRef
53.
go back to reference Chauhan S, Gaur A, Tripathi M, et al. Unintentional combined epidural and subdural block. Case report. Reg Anesth. 1995;20:249–51.PubMed Chauhan S, Gaur A, Tripathi M, et al. Unintentional combined epidural and subdural block. Case report. Reg Anesth. 1995;20:249–51.PubMed
54.
go back to reference Mizuyama K, Dohi S. An accidental subdural injection of a local anaesthetic resulting in respiratory depression. Can J Anaesth. 1993;40:83–4.PubMed Mizuyama K, Dohi S. An accidental subdural injection of a local anaesthetic resulting in respiratory depression. Can J Anaesth. 1993;40:83–4.PubMed
55.
go back to reference Turnbull DK, Shepherd DB. Post-dural puncture headache: pathogenesis, prevention and treatment. Br J Anaesth. 2003;91:718–29.PubMedCrossRef Turnbull DK, Shepherd DB. Post-dural puncture headache: pathogenesis, prevention and treatment. Br J Anaesth. 2003;91:718–29.PubMedCrossRef
56.
go back to reference MacLean CA, Bachman DT. Documented arterial gas embolism after spinal epidural injection. Ann Emerg Med. 2001;38:592–5.PubMedCrossRef MacLean CA, Bachman DT. Documented arterial gas embolism after spinal epidural injection. Ann Emerg Med. 2001;38:592–5.PubMedCrossRef
57.
go back to reference Ammirati M, Perino F. Symptomatic air trapped in the spine after lumbar epidural corticosteroid injection. Case report. J Neurosurg Spine. 2006;5:359–61.PubMedCrossRef Ammirati M, Perino F. Symptomatic air trapped in the spine after lumbar epidural corticosteroid injection. Case report. J Neurosurg Spine. 2006;5:359–61.PubMedCrossRef
58.
go back to reference Finn K, Case J. Disk entry: a complication of transforaminal epidural injection—a case report. Arch Phys Med Rehabil. 2005;86:1489–91.PubMedCrossRef Finn K, Case J. Disk entry: a complication of transforaminal epidural injection—a case report. Arch Phys Med Rehabil. 2005;86:1489–91.PubMedCrossRef
59.
go back to reference Armitage EN. Lumbar and thoracic epidural. In: Wildsmith JAW, Armitage EN, editors. Principles and practice of regional anesthesia. New York: Churchill Livingstone; 1987. Armitage EN. Lumbar and thoracic epidural. In: Wildsmith JAW, Armitage EN, editors. Principles and practice of regional anesthesia. New York: Churchill Livingstone; 1987.
60.
go back to reference Morgan GE, Mikhail MS, Murray MJ. Clinical anesthesiology. 4th ed. New York: Lange Medical Books/McGraw-Hill Medical Publishing Division; 2006. Morgan GE, Mikhail MS, Murray MJ. Clinical anesthesiology. 4th ed. New York: Lange Medical Books/McGraw-Hill Medical Publishing Division; 2006.
61.
go back to reference Botwin KP, Thomas S, Gruber RD. Radiation exposure of the spinal interventionalist performing fluoroscopically guided lumbar transforaminal epidural steroid injections. Arch Phys Med Rehabil. 2002;83:697–701.PubMedCrossRef Botwin KP, Thomas S, Gruber RD. Radiation exposure of the spinal interventionalist performing fluoroscopically guided lumbar transforaminal epidural steroid injections. Arch Phys Med Rehabil. 2002;83:697–701.PubMedCrossRef
62.
go back to reference Manchikanti L, Cash KA, Moss TL, et al. Radiation exposure to the physician in interventional pain management. Pain Physician. 2002;5:385–93.PubMed Manchikanti L, Cash KA, Moss TL, et al. Radiation exposure to the physician in interventional pain management. Pain Physician. 2002;5:385–93.PubMed
63.
go back to reference Manchikanti L, Cash KA, Moss TL, et al. Effectiveness of protective measures in reducing risk of radiation in interventional pain management: a prospective evaluation. Pain Physician. 2003;6:301–5.PubMed Manchikanti L, Cash KA, Moss TL, et al. Effectiveness of protective measures in reducing risk of radiation in interventional pain management: a prospective evaluation. Pain Physician. 2003;6:301–5.PubMed
64.
go back to reference National Council on Radiation Protection and Measurements (NCRP). Report No. 116 Limitation of exposure to ionizing radiation. Bethesda, MD: NCRP Publications; 1993. National Council on Radiation Protection and Measurements (NCRP). Report No. 116 Limitation of exposure to ionizing radiation. Bethesda, MD: NCRP Publications; 1993.
65.
go back to reference Fishman SM, Smith H, Meleger A, et al. Radiation safety in pain medicine. Reg Anesth Pain Med. 2002;27:296–305.PubMedCrossRef Fishman SM, Smith H, Meleger A, et al. Radiation safety in pain medicine. Reg Anesth Pain Med. 2002;27:296–305.PubMedCrossRef
66.
go back to reference Mahesh M. Patient radiation exposure issues. Radiographics. 2001;21:1033–45.PubMed Mahesh M. Patient radiation exposure issues. Radiographics. 2001;21:1033–45.PubMed
67.
go back to reference Fozzard HA, Lee PJ, Lipkind GM. Mechanism of local anesthetic drug action on voltage-gated sodium channels. Curr Pharm Des. 2005;11:2671–86.PubMedCrossRef Fozzard HA, Lee PJ, Lipkind GM. Mechanism of local anesthetic drug action on voltage-gated sodium channels. Curr Pharm Des. 2005;11:2671–86.PubMedCrossRef
68.
go back to reference Simon DL, Kunz RD, German JD, et al. Allergic or pseudoallergic reaction following epidural steroid deposition and skin testing. Reg Anesth. 1989;14:253–5.PubMed Simon DL, Kunz RD, German JD, et al. Allergic or pseudoallergic reaction following epidural steroid deposition and skin testing. Reg Anesth. 1989;14:253–5.PubMed
70.
go back to reference Manchilanti L. Role of neuraxial steroids in interventional pain management. Pain Physician. 2002;5:182–99. Manchilanti L. Role of neuraxial steroids in interventional pain management. Pain Physician. 2002;5:182–99.
71.
go back to reference Mertes PM, Laxenaire MC, Alla F, Groupe d’Etudes des Réactions Anaphylactoïdes Peranesthésiques. Anaphylactic and anaphylactoid reactions occurring during anesthesia in France in 1999–2000. Anesthesiology. 2003;99:536–45.PubMedCrossRef Mertes PM, Laxenaire MC, Alla F, Groupe d’Etudes des Réactions Anaphylactoïdes Peranesthésiques. Anaphylactic and anaphylactoid reactions occurring during anesthesia in France in 1999–2000. Anesthesiology. 2003;99:536–45.PubMedCrossRef
72.
go back to reference Meth MJ, Maibach HL. Current understanding of contrast media reactions and implications for clinical management. Drug Saf. 2006;29:133–41.PubMedCrossRef Meth MJ, Maibach HL. Current understanding of contrast media reactions and implications for clinical management. Drug Saf. 2006;29:133–41.PubMedCrossRef
73.
go back to reference Namasivayam S, Kalra MK, Torres WE, et al. Adverse reactions to intravenous iodinated contrast media: a primer for radiologists. Emerg Radiol. 2006;12:210–5.PubMedCrossRef Namasivayam S, Kalra MK, Torres WE, et al. Adverse reactions to intravenous iodinated contrast media: a primer for radiologists. Emerg Radiol. 2006;12:210–5.PubMedCrossRef
74.
go back to reference Safriel Y, Ali M, Hayt M, et al. Gadolinium use in spine procedures for patients with allergy to iodinated contrast—experience of 127 procedures. AJNR Am J Neuroradiol. 2006;27:1194–7.PubMed Safriel Y, Ali M, Hayt M, et al. Gadolinium use in spine procedures for patients with allergy to iodinated contrast—experience of 127 procedures. AJNR Am J Neuroradiol. 2006;27:1194–7.PubMed
75.
go back to reference Cohan RH, Matsumoto JS, Quagliano PV. Manual on contrast media. 4th ed. Reston, VA: American College of Radiology; 1998. Cohan RH, Matsumoto JS, Quagliano PV. Manual on contrast media. 4th ed. Reston, VA: American College of Radiology; 1998.
Metadata
Title
Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections
Authors
Bradly S. Goodman
Lyle W. F. Posecion
Srinivas Mallempati
Matt Bayazitoglu
Publication date
01-12-2008
Publisher
Humana Press Inc
Published in
Current Reviews in Musculoskeletal Medicine / Issue 3-4/2008
Electronic ISSN: 1935-9748
DOI
https://doi.org/10.1007/s12178-008-9035-2

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