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Indian Journal of Otolaryngology and Head & Neck Surgery

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29-12-2022 | CO2 Laser | Original Article

Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience

Authors: Navid Ahmadi, Danielle Stone, Murray Stokan, Hedley Coleman, Gillian Heller, Mark Smith, Faruque Riffat, Akshay Kudpaje, Michael Veness, Carsten E Palme

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 2/2023

Abstract

Introduction

Early laryngeal carcinomas may be treated by transoral laser microsurgery (TLM) or external beam radiotherapy. We review our experience of surgical treatment of laryngeal pre-malignant and malignant lesions over the past 15 years in a high-volume head neck unit.

Methods

A review of a prospective patient database of patients with laryngeal SCC, who were treated with CO₂ TLM between 2004 and 2019 was carried out.

Results

83 patients with a mean age of 67.7 (SD: 10.6) years underwent primary curative TLM for T1a/b SCC. 5-year overall survival was 93.2% (95%CI 86.9–100%), disease free survival was 86.0% (95%CI 78.1–94.6%), locoregional control was 91.2% (95%CI: 85.1–97.7%) and larynx preservation rate of 95.1% at 5 years.

Conclusion

TLM is an excellent treatment modality for T1 early glottic SCC, with excellent locoregional control and disease-free survival. It is minimally invasive, outpatient-based, and cost-effective procedure preserving upper aerodigestive tract dysfunction for all activities of daily living.

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Title: Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience
Authors: Navid Ahmadi
Danielle Stone
Murray Stokan
Hedley Coleman
Gillian Heller
Mark Smith
Faruque Riffat
Akshay Kudpaje
Michael Veness
Carsten E Palme
Publication date: 29-12-2022
Publisher: Springer India
Keywords: CO2 Laser
Radiotherapy
Laser
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 2/2023
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-022-03392-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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