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Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2022

16-06-2020 | Tuberculosis | Other Articles

Submandibular Gland Tuberculosis: A Literature Review and Update

Authors: Poras Chaudhary, Rica Singh, Sam B. Padala, Ashutosh Nagpal, Amrit K. Gupta, Romesh Lal

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 2/2022

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Abstract

Submandibular salivary gland is an uncommon and unusual site for tuberculosis. It is a rare extrapulmonary manifestation of a common infection caused by Mycobacterium tubercle bacillus. Submandibular gland TB can be due to primary or secondary infection. The clinical features are non-specific and depend on its manifestations. A delay in diagnosis is common because of the rarity of disease. Direct histological examination is the best method of diagnosis. As the disease is curable with antituberculous drugs; treatment should not be withheld in suspected cases until the diagnosis is confirmed. Surgery is indicated for non-responsive disease and complications. Till date, only 15 cases have been reported in the literature. First case was reported in the year 1990. The authors encountered three cases in last 10 years. The aims of this study are to review clinical presentation, epidemiological features, diagnostic methods and to provide our data and guidelines for optimum management of this rare pathology.
Literature
1.
go back to reference Kumar S, Dev A (1990) Primary tuberculosis of bilateral submandibular salivary glands. Indian J Otolaryngol 42:68–69CrossRef Kumar S, Dev A (1990) Primary tuberculosis of bilateral submandibular salivary glands. Indian J Otolaryngol 42:68–69CrossRef
2.
go back to reference Park K (2011) Epidemiology of communicable diseases. Park’s textbook of preventive and social medicine. 21st ed. Bhanot Jabalpur pp 64–68 Park K (2011) Epidemiology of communicable diseases. Park’s textbook of preventive and social medicine. 21st ed. Bhanot Jabalpur pp 64–68
4.
go back to reference Virmani N, Dabholkar J (2019) Primary tubercular sialadenitis—a diagnostic dilemma. Iran J Otorhinolaryngol 31:45–50PubMedPubMedCentral Virmani N, Dabholkar J (2019) Primary tubercular sialadenitis—a diagnostic dilemma. Iran J Otorhinolaryngol 31:45–50PubMedPubMedCentral
5.
go back to reference Gupta KB, Yadav SPS, Sarita, Manchanda M (2005) Primary pharyngeal tuberculosis. Lung India 22:127–129 Gupta KB, Yadav SPS, Sarita, Manchanda M (2005) Primary pharyngeal tuberculosis. Lung India 22:127–129
6.
7.
go back to reference Bottini DJ, Garelli A, Felici M, Galante V, Cervelli V (2007) Primary tuberculosis of the submandibular salivary gland. J Craniofac Surg 18:218–219PubMed Bottini DJ, Garelli A, Felici M, Galante V, Cervelli V (2007) Primary tuberculosis of the submandibular salivary gland. J Craniofac Surg 18:218–219PubMed
9.
10.
go back to reference Kasim SK, Namawar E, Yunus MRM (2015) A rare case of primary tuberculosis of the submandibular gland. Egyptian J ENT Allied Sci 16:87–89 Kasim SK, Namawar E, Yunus MRM (2015) A rare case of primary tuberculosis of the submandibular gland. Egyptian J ENT Allied Sci 16:87–89
11.
go back to reference Nachlas NE, Johns ME (1991) Physiology of the salivary glands. In: Paparella MM, Shumrick DA, Gluckman JL et al (eds) Otolaryngology, vol 1, 3rd edn. Lippincott Williams & Wilkins, A Wolters Kluwer Business, Philadelphia, pp 391–405 Nachlas NE, Johns ME (1991) Physiology of the salivary glands. In: Paparella MM, Shumrick DA, Gluckman JL et al (eds) Otolaryngology, vol 1, 3rd edn. Lippincott Williams & Wilkins, A Wolters Kluwer Business, Philadelphia, pp 391–405
12.
go back to reference Ataman M, Sozeri B, Ozcelik T, Gedikoglu G (1992) Tuberculosis of the parotid salivary gland. Auris Nasus Larynx 19:271–273CrossRefPubMed Ataman M, Sozeri B, Ozcelik T, Gedikoglu G (1992) Tuberculosis of the parotid salivary gland. Auris Nasus Larynx 19:271–273CrossRefPubMed
13.
go back to reference Bhargava S, Watmough DJ, Chisti FA, Sathar SA (1996) Tuberculosis of the parotid gland—diagnosis by CT. Br J Radiol 69:1181–1183CrossRefPubMed Bhargava S, Watmough DJ, Chisti FA, Sathar SA (1996) Tuberculosis of the parotid gland—diagnosis by CT. Br J Radiol 69:1181–1183CrossRefPubMed
14.
go back to reference Abdel RAAK, Mukherji S (2017) Imaging of sialadenitis. Neuroradiol J 30:205–215CrossRef Abdel RAAK, Mukherji S (2017) Imaging of sialadenitis. Neuroradiol J 30:205–215CrossRef
15.
go back to reference Kim YH, Jeong WJ, Jung KY, Sung MW, Kim KH, Kim CS (2005) Diagnosis of major salivary gland tuberculosis: experience of eight cases and review of the literature. Acta Otolaryngol 125:1318–1322CrossRefPubMed Kim YH, Jeong WJ, Jung KY, Sung MW, Kim KH, Kim CS (2005) Diagnosis of major salivary gland tuberculosis: experience of eight cases and review of the literature. Acta Otolaryngol 125:1318–1322CrossRefPubMed
16.
go back to reference Iseri M, Aydyner O, Celik L, Peker O (2005) Tuberculosis of the parotid gland. J Laryngol Otol 119:311–313CrossRefPubMed Iseri M, Aydyner O, Celik L, Peker O (2005) Tuberculosis of the parotid gland. J Laryngol Otol 119:311–313CrossRefPubMed
17.
go back to reference Moure C, Mbuyamba S, Bruniau A, Gbaguidi C, Testelin S, Boutemy M et al (2006) Tuberculosis of the submandibular gland: a case report. Rev Stomatol Chir Maxillofac 107:115–118CrossRefPubMed Moure C, Mbuyamba S, Bruniau A, Gbaguidi C, Testelin S, Boutemy M et al (2006) Tuberculosis of the submandibular gland: a case report. Rev Stomatol Chir Maxillofac 107:115–118CrossRefPubMed
18.
go back to reference Mahesh KV, Madhavan R, Narayanan S (2014) Polymerase chain reaction targeting insertion sequence for the diagnosis of extrapulmonary tuberculosis. Indian J Med Res 139:161–166 Mahesh KV, Madhavan R, Narayanan S (2014) Polymerase chain reaction targeting insertion sequence for the diagnosis of extrapulmonary tuberculosis. Indian J Med Res 139:161–166
19.
go back to reference Dadwal M (2011) Primary submandibular gland tuberculosis: an unusual cause of submandibular salivary gland enlargement. Indian J Otolaryngol Head Neck Surg 63:298–299CrossRefPubMedPubMedCentral Dadwal M (2011) Primary submandibular gland tuberculosis: an unusual cause of submandibular salivary gland enlargement. Indian J Otolaryngol Head Neck Surg 63:298–299CrossRefPubMedPubMedCentral
20.
go back to reference Tsutomu S, Kyoko N, Nobuhiko F (1999) Tuberculous sialadenitis of submandibular gland. Kita Kanto Med J 49:177–180CrossRef Tsutomu S, Kyoko N, Nobuhiko F (1999) Tuberculous sialadenitis of submandibular gland. Kita Kanto Med J 49:177–180CrossRef
Metadata
Title
Submandibular Gland Tuberculosis: A Literature Review and Update
Authors
Poras Chaudhary
Rica Singh
Sam B. Padala
Ashutosh Nagpal
Amrit K. Gupta
Romesh Lal
Publication date
16-06-2020
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 2/2022
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-020-01912-y

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