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Published in: Neurocritical Care 3/2010

01-12-2010 | Original Article

Bedside Use of a Dual Aortic Balloon Occlusion for the Treatment of Cerebral Vasospasm

Authors: Geoffrey Appelboom, Dorothea Strozyk, Brian Y. Hwang, Joan Prowda, Neeraj Badjatia, Raimund Helbok, Philip M. Meyers

Published in: Neurocritical Care | Issue 3/2010

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Abstract

Background

Delayed ischemic neurological deficits (DIND) due to cerebral vasospasm remains a major cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage (aSAH). Methods to prevent DIND remain limited both in safety and efficacy. A novel intra-aortic dual balloon catheter (NeuroFloTM: CoAxia, Maple Grove, MN) is under investigation for treatment of ischemic stroke, including DIND. Because this technique does not require cerebral artery navigation, it may be useful as a bedside procedure, outside of the conventional angiography suite. We report the first case of ultrasound-guided application of the NeuroFloTM system at bedside in the Neurological Intensive Care Unit.

Methods

A 52-year-old woman presented with Hunt Hess IV aSAH complicated by medically refractory cerebral vasospasm. Despite surgical clipping of her aneurysm, the patient remained critically ill, failing maximal conventional medical therapy. For that reason, the NeuroFloTM system was deployed using two-dimensional, spectral and color-flow Doppler ultrasound guidance at the patient’s bedside while maintaining all forms of cerebral blood flow monitoring.

Results

The procedure was well tolerated and there was no complication.

Conclusion

Bedside application of the NeuroFloTM system may be safely performed in critically ill patients. The NeuroFloTM system is under investigation for treatment of refractory cerebral vasospasm to prevent delayed ischemic neurological disease.
Literature
1.
go back to reference Lylyk P, Vila JF, Miranda C, Ferrario A, Romero R, Cohen JE. Partial aortic obstruction improves cerebral perfusion and clinical symptoms in patients with symptomatic vasospasm. Neurol Res. 2005;17:S129–35.CrossRef Lylyk P, Vila JF, Miranda C, Ferrario A, Romero R, Cohen JE. Partial aortic obstruction improves cerebral perfusion and clinical symptoms in patients with symptomatic vasospasm. Neurol Res. 2005;17:S129–35.CrossRef
2.
go back to reference Hammer M, Jovin T, Wahr JA, Heiss W-D. Partial occlusion of the descending aorta increases cerebral blood flow in a nonstroke porcine model. Cerebrovasc Dis. 2009;28:406–10.CrossRefPubMed Hammer M, Jovin T, Wahr JA, Heiss W-D. Partial occlusion of the descending aorta increases cerebral blood flow in a nonstroke porcine model. Cerebrovasc Dis. 2009;28:406–10.CrossRefPubMed
4.
go back to reference Liebeskind DS. Aortic occlusion for cerebral ischemia: from theory to practice. Curr Cardiol Rep. 2008;10:31–6.CrossRefPubMed Liebeskind DS. Aortic occlusion for cerebral ischemia: from theory to practice. Curr Cardiol Rep. 2008;10:31–6.CrossRefPubMed
5.
go back to reference Doring BL, Kerr ME, Lovasik DA, Thayer T. Factors that contribute to complications during intrahospital transport of the critically ill. J Neurosci Nurs. 1999;31:80–6.CrossRefPubMed Doring BL, Kerr ME, Lovasik DA, Thayer T. Factors that contribute to complications during intrahospital transport of the critically ill. J Neurosci Nurs. 1999;31:80–6.CrossRefPubMed
7.
go back to reference Gleeson TG, Bulugahapitiya S. Contrast-induced nephropathy. AJR Am J Roentgenol. 2004;183:1673–89.PubMed Gleeson TG, Bulugahapitiya S. Contrast-induced nephropathy. AJR Am J Roentgenol. 2004;183:1673–89.PubMed
8.
go back to reference Uflacker R, Schönholz C, Papamitisakis N, SENTIS trial. Interim report of the SENTIS trial: cerebral perfusion augmentation via partial aortic occlusion in acute ischemic stroke. J Cardiovasc Surg (Torino). 2008;49:715–21. Uflacker R, Schönholz C, Papamitisakis N, SENTIS trial. Interim report of the SENTIS trial: cerebral perfusion augmentation via partial aortic occlusion in acute ischemic stroke. J Cardiovasc Surg (Torino). 2008;49:715–21.
Metadata
Title
Bedside Use of a Dual Aortic Balloon Occlusion for the Treatment of Cerebral Vasospasm
Authors
Geoffrey Appelboom
Dorothea Strozyk
Brian Y. Hwang
Joan Prowda
Neeraj Badjatia
Raimund Helbok
Philip M. Meyers
Publication date
01-12-2010
Publisher
Humana Press Inc
Published in
Neurocritical Care / Issue 3/2010
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-010-9442-2

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