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Published in: Endocrine Pathology 1/2024

Open Access 16-02-2024 | Parathyroid Cancer | Images in Endocrine Pathology

Not All Parafibromin Deficiency Relates to Parathyroid Carcinoma: The Role of Morphological Assessment

Author: C. Christofer Juhlin

Published in: Endocrine Pathology | Issue 1/2024

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Excerpt

A male in his early thirties, without any prior medical history, presented with a history of fatigue. Upon examination, mild hypercalcemia and elevated levels of parathyroid hormone (PTH) were observed. The patient was subsequently referred to our endocrine surgery department. Ultrasound and sestamibi scintigraphy revealed an enlarged right superior parathyroid gland measuring 20 mm. The patient had no family history suggestive of parathyroid disease or MEN1-related manifestations. A focused parathyroidectomy was performed. …
Literature
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go back to reference Gill AJ, Lim G, Cheung VKY, Andrici J, Perry-Keene JL, Paik J, Sioson L, Clarkson A, Sheen A, Luxford C, Elston MS, Meyer-Rochow GY, Nano MT, Kruijff S, Engelsman AF, Sywak M, Sidhu SB, Delbridge LW, Robinson BG, Marsh DJ, Toon CW, Chou A, Clifton-Bligh RJ (2018) Parafibromin-deficient (HPT-JT Type, CDC73 mutated) parathyroid tumors demonstrate distinctive morphologic features. Am J Surg Pathol. https://doi.org/10.1097/PAS.0000000000001017CrossRefPubMedPubMedCentral Gill AJ, Lim G, Cheung VKY, Andrici J, Perry-Keene JL, Paik J, Sioson L, Clarkson A, Sheen A, Luxford C, Elston MS, Meyer-Rochow GY, Nano MT, Kruijff S, Engelsman AF, Sywak M, Sidhu SB, Delbridge LW, Robinson BG, Marsh DJ, Toon CW, Chou A, Clifton-Bligh RJ (2018) Parafibromin-deficient (HPT-JT Type, CDC73 mutated) parathyroid tumors demonstrate distinctive morphologic features. Am J Surg Pathol. https://​doi.​org/​10.​1097/​PAS.​0000000000001017​CrossRefPubMedPubMedCentral
Metadata
Title
Not All Parafibromin Deficiency Relates to Parathyroid Carcinoma: The Role of Morphological Assessment
Author
C. Christofer Juhlin
Publication date
16-02-2024
Publisher
Springer US
Published in
Endocrine Pathology / Issue 1/2024
Print ISSN: 1046-3976
Electronic ISSN: 1559-0097
DOI
https://doi.org/10.1007/s12022-024-09804-5

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