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Published in: Endocrine 2/2014

01-06-2014 | Editorial

Is there a need for yet another staging system for differentiated thyroid cancer?

Author: Michael Bouvet

Published in: Endocrine | Issue 2/2014

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Excerpt

Papillary thyroid carcinoma and follicular thyroid carcinoma together comprise a generally indolent group of cancers known as differentiated thyroid carcinomas (DTCs). In 2014, there will be an estimated 62,980 new cases of differentiated thyroid cancer, and the incidence is rising faster than any other cancer in the USA [1]. Although the prognosis of DTC is generally good, a small subset of patients eventually die of the disease and up to 30 % of patients experience a recurrence of their disease after 30 years of follow-up [2]. As a result, a number of studies have identified various clinical and pathologic predictors for DTC and devised risk-group stratification or staging systems to select those at high risk of disease recurrence for more aggressive surgical and adjuvant treatment, while those at low risk would be spared aggressive treatment. …
Literature
3.
go back to reference American Thyroid Association Guidelines Taskforce on Thyroid, N., Differentiated Thyroid, C., Cooper, D.S., Doherty, G.M., Haugen, B.R., Kloos, R.T., Lee, S.L., Mandel, S.J., Mazzaferri, E.L., McIver, B., Pacini, F., Schlumberger, M., Sherman, S.I., Steward, D.L., Tuttle, R.M.: Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19(11), 1167–1214 (2009). doi:10.1089/thy.2009.0110 American Thyroid Association Guidelines Taskforce on Thyroid, N., Differentiated Thyroid, C., Cooper, D.S., Doherty, G.M., Haugen, B.R., Kloos, R.T., Lee, S.L., Mandel, S.J., Mazzaferri, E.L., McIver, B., Pacini, F., Schlumberger, M., Sherman, S.I., Steward, D.L., Tuttle, R.M.: Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19(11), 1167–1214 (2009). doi:10.​1089/​thy.​2009.​0110
4.
go back to reference I.D. Hay, C.S. Grant, W.F. Taylor, W.M. McConahey, Ipsilateral lobectomy versus bilateral lobar resection in papillary thyroid carcinoma: a retrospective analysis of surgical outcome using a novel prognostic scoring system. Surgery 102(6), 1088–1095 (1987)PubMed I.D. Hay, C.S. Grant, W.F. Taylor, W.M. McConahey, Ipsilateral lobectomy versus bilateral lobar resection in papillary thyroid carcinoma: a retrospective analysis of surgical outcome using a novel prognostic scoring system. Surgery 102(6), 1088–1095 (1987)PubMed
5.
go back to reference B. Cady, R. Rossi, An expanded view of risk-group definition in differentiated thyroid carcinoma. Surgery 104(6), 947–953 (1988)PubMed B. Cady, R. Rossi, An expanded view of risk-group definition in differentiated thyroid carcinoma. Surgery 104(6), 947–953 (1988)PubMed
6.
go back to reference D.P. Byar, S.B. Green, P. Dor, E.D. Williams, J. Colon, H.A. van Gilse, M. Mayer, R.J. Sylvester, M. van Glabbeke, A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur. J. Cancer 15(8), 1033–1041 (1979)PubMedCrossRef D.P. Byar, S.B. Green, P. Dor, E.D. Williams, J. Colon, H.A. van Gilse, M. Mayer, R.J. Sylvester, M. van Glabbeke, A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur. J. Cancer 15(8), 1033–1041 (1979)PubMedCrossRef
9.
go back to reference D. Mankarios, P. Baade, P. Youl, R.H. Mortimer, A.A. Onitilo, A. Russell, S.A. Doi, Validation of the QTNM staging system for cancer-specific survival in patients with differentiated thyroid cancer. Endocrine (2013). doi:10.1007/s12020-013-0078-9 PubMed D. Mankarios, P. Baade, P. Youl, R.H. Mortimer, A.A. Onitilo, A. Russell, S.A. Doi, Validation of the QTNM staging system for cancer-specific survival in patients with differentiated thyroid cancer. Endocrine (2013). doi:10.​1007/​s12020-013-0078-9 PubMed
10.
go back to reference M. Xing, A.S. Alzahrani, K.A. Carson, D. Viola, R. Elisei, B. Bendlova, L. Yip, C. Mian, F. Vianello, R.M. Tuttle, E. Robenshtok, J.A. Fagin, E. Puxeddu, L. Fugazzola, A. Czarniecka, B. Jarzab, C.J. O’Neill, M.S. Sywak, A.K. Lam, G. Riesco-Eizaguirre, P. Santisteban, H. Nakayama, R.P. Tufano, S.I. Pai, M.A. Zeiger, W.H. Westra, D.P. Clark, R. Clifton-Bligh, D. Sidransky, P.W. Ladenson, V. Sykorova, Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA 309(14), 1493–1501 (2013). doi:10.1001/jama2013.3190 PubMedCentralPubMedCrossRef M. Xing, A.S. Alzahrani, K.A. Carson, D. Viola, R. Elisei, B. Bendlova, L. Yip, C. Mian, F. Vianello, R.M. Tuttle, E. Robenshtok, J.A. Fagin, E. Puxeddu, L. Fugazzola, A. Czarniecka, B. Jarzab, C.J. O’Neill, M.S. Sywak, A.K. Lam, G. Riesco-Eizaguirre, P. Santisteban, H. Nakayama, R.P. Tufano, S.I. Pai, M.A. Zeiger, W.H. Westra, D.P. Clark, R. Clifton-Bligh, D. Sidransky, P.W. Ladenson, V. Sykorova, Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA 309(14), 1493–1501 (2013). doi:10.​1001/​jama2013.​3190 PubMedCentralPubMedCrossRef
Metadata
Title
Is there a need for yet another staging system for differentiated thyroid cancer?
Author
Michael Bouvet
Publication date
01-06-2014
Publisher
Springer US
Published in
Endocrine / Issue 2/2014
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-014-0203-4

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