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Current Rheumatology Reports
Published in: Current Rheumatology Reports 12/2018

01-12-2018 | Spondyloarthritis (M Khan, Section Editor)

Radiographic Progression in Ankylosing Spondylitis: From Prognostication to Disease Modification

Authors: Ismail Sari, Nigil Haroon

Published in: Current Rheumatology Reports | Issue 12/2018

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Abstract

Purpose of Review

Pain, functional limitation, and spinal damage are the three main domains that have significant impact on various aspects of axial spondyloarthritis (axSpA).

Recent Findings

Several randomized controlled trials (RCTs) showed a beneficial effect of non-steroid ant-inflammatory drugs (NSAIDs) and biologic treatments on pain and function. The effect of available treatments on spinal damage is still of interest and is being studied.

Summary

In this article, we review the literature on radiographic progression in axSpA. We discuss the natural course of spinal progression, predictors of spinal damage, and the effect of lifestyle changes and medications on radiographic progression in axSpA.
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Metadata
Title
Radiographic Progression in Ankylosing Spondylitis: From Prognostication to Disease Modification
Authors
Ismail Sari
Nigil Haroon
Publication date
01-12-2018
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 12/2018
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-018-0795-4

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