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Current Pain and Headache Reports
Published in: Current Pain and Headache Reports 11/2014

01-11-2014 | Migraine (R Cowan, Section Editor)

Migraine is Associated With Altered Processing of Sensory Stimuli

Authors: Andrea M. Harriott, Todd J. Schwedt

Published in: Current Pain and Headache Reports | Issue 11/2014

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Abstract

Migraine is associated with derangements in perception of multiple sensory modalities including vision, hearing, smell, and somatosensation. Compared to people without migraine, migraineurs have lower discomfort thresholds in response to special sensory stimuli as well as to mechanical and thermal noxious stimuli. Likewise, the environmental triggers of migraine attacks, such as odors and flashing lights, highlight basal abnormalities in sensory processing and integration. These alterations in sensory processing and perception in migraineurs have been investigated via physiological studies and functional brain imaging studies. Investigations have demonstrated that migraineurs during and between migraine attacks have atypical stimulus-induced activations of brainstem, subcortical, and cortical regions that participate in sensory processing. A lack of normal habituation to repetitive stimuli during the interictal state and a tendency towards development of sensitization likely contribute to migraine-related alterations in sensory processing.
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Metadata
Title
Migraine is Associated With Altered Processing of Sensory Stimuli
Authors
Andrea M. Harriott
Todd J. Schwedt
Publication date
01-11-2014
Publisher
Springer US
Published in
Current Pain and Headache Reports / Issue 11/2014
Print ISSN: 1531-3433
Electronic ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-014-0458-8

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