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01-10-2015 | Therapeutics and Medical Management (E Shane and R Adler, Section Editors)

Bone Imaging and Fracture Risk after Spinal Cord Injury

Authors: W. Brent Edwards, Thomas J. Schnitzer

Published in: Current Osteoporosis Reports | Issue 5/2015

Abstract

Spinal cord injury (SCI) is characterized by marked bone loss and an increased risk of fracture with high complication rate. Recent research based on advanced imaging analysis, including quantitative computed tomography (QCT) and patient-specific finite element (FE) modeling, has provided new and important insights into the magnitude and temporal pattern of bone loss, as well as the associated changes to bone structure and strength, following SCI. This work has illustrated the importance of early therapeutic treatment to prevent bone loss after SCI and may someday serve as the basis for a clinical fracture risk assessment tool for the SCI population. This review provides an update on the epidemiology of fracture after SCI and discusses new findings and significant developments related to bone loss and fracture risk assessment in the SCI population based on QCT analysis and patient-specific FE modeling.

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Title: Bone Imaging and Fracture Risk after Spinal Cord Injury
Authors: W. Brent Edwards
Thomas J. Schnitzer
Publication date: 01-10-2015
Publisher: Springer US
Published in: Current Osteoporosis Reports / Issue 5/2015
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-015-0288-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Bone Imaging and Fracture Risk after Spinal Cord Injury

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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