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Current Hypertension Reports
Published in: Current Hypertension Reports 10/2014

01-10-2014 | Pathogenesis of Hypertension (W Elliott, Section Editor)

Obstructive Sleep Apnea and Hypertension: a Critical Review

Author: Vahid Mohsenin

Published in: Current Hypertension Reports | Issue 10/2014

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Abstract

Obstructive sleep apnea (OSA) is a prevalent sleep disorder which is characterized by recurrent upper closure with oxygen desaturation and sleep disruption. OSA increases the risk of vascular disorders in the form of stroke, myocardial infarction, congestive heart failure, and hypertension. The mechanisms underlying the vascular disorders are several and include intermittent hypoxia with release of cytokines, angiogenic inhibitors, free radicals, and adhesion molecules. During apneas, arterial blood pressure gradually rises and surges abruptly after the termination of apnea. Two thirds of patients with OSA will ultimately have diurnal hypertension. This review discusses the literature supporting the significant role of OSA in hypertension and the effect of OSA treatment on blood pressure.
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Metadata
Title
Obstructive Sleep Apnea and Hypertension: a Critical Review
Author
Vahid Mohsenin
Publication date
01-10-2014
Publisher
Springer US
Published in
Current Hypertension Reports / Issue 10/2014
Print ISSN: 1522-6417
Electronic ISSN: 1534-3111
DOI
https://doi.org/10.1007/s11906-014-0482-4

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