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Published in: Current Heart Failure Reports 2/2013

01-06-2013 | Pathophysiology: Neuroendocrine, Vascular, and Metabolic Factors (S.D. Katz, Section Editor)

High-Intensity Aerobic Interval Exercise in Chronic Heart Failure

Authors: Philippe Meyer, Mathieu Gayda, Martin Juneau, Anil Nigam

Published in: Current Heart Failure Reports | Issue 2/2013

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Abstract

Aerobic exercise training is strongly recommended in patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF) to improve symptoms and quality of life. Moderate-intensity aerobic continuous exercise (MICE) is the best established training modality in HF patients. For about a decade, however, another training modality, high-intensity aerobic interval exercise (HIIE), has aroused considerable interest in cardiac rehabilitation. Originally used by athletes, HIIE consists of repeated bouts of high-intensity exercise interspersed with recovery periods. The rationale for its use is to increase exercise time spent in high-intensity zones, thereby increasing the training stimulus. Several studies have demonstrated that HIIE is more effective than MICE, notably for improving exercise capacity in patients with HF. The aim of the present review is to describe the general principles of HIIE prescription, the acute physiological effects, the longer-term training effects, and finally the future perspectives of HIIE in patients with HF.
Literature
1.
go back to reference Braunwald E. Heart disease: a textbook of cardiovascular medicine. 3rd ed. Philadelphia: Saunders; 1988. Braunwald E. Heart disease: a textbook of cardiovascular medicine. 3rd ed. Philadelphia: Saunders; 1988.
2.
go back to reference Jugdutt BI, Michorowski BL, Kappagoda CT. Exercise training after anterior Q wave myocardial infarction: importance of regional left ventricular function and topography. J Am Coll Cardiol. 1988;12:362–72.PubMedCrossRef Jugdutt BI, Michorowski BL, Kappagoda CT. Exercise training after anterior Q wave myocardial infarction: importance of regional left ventricular function and topography. J Am Coll Cardiol. 1988;12:362–72.PubMedCrossRef
3.
go back to reference Sullivan MJ, Higginbotham MB, Cobb FR. Exercise training in patients with severe left ventricular dysfunction. Hemodynamic and metabolic effects. Circulation. 1988;78:506–15.PubMedCrossRef Sullivan MJ, Higginbotham MB, Cobb FR. Exercise training in patients with severe left ventricular dysfunction. Hemodynamic and metabolic effects. Circulation. 1988;78:506–15.PubMedCrossRef
4.
go back to reference van Tol BA, Huijsmans RJ, Kroon DW, et al. Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: a meta-analysis. Eur J Heart Fail. 2006;8:841–50.PubMedCrossRef van Tol BA, Huijsmans RJ, Kroon DW, et al. Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: a meta-analysis. Eur J Heart Fail. 2006;8:841–50.PubMedCrossRef
5.
go back to reference Smart N, Marwick TH. Exercise training for patients with heart failure: a systematic review of factors that improve mortality and morbidity. Am J Med. 2004;116:693–706.PubMedCrossRef Smart N, Marwick TH. Exercise training for patients with heart failure: a systematic review of factors that improve mortality and morbidity. Am J Med. 2004;116:693–706.PubMedCrossRef
6.
go back to reference Piepoli MF, Davos C, Francis DP, et al. Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH). BMJ. 2004;328:189.PubMedCrossRef Piepoli MF, Davos C, Francis DP, et al. Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH). BMJ. 2004;328:189.PubMedCrossRef
7.
go back to reference O’Connor CM, Whellan DJ, Lee KL, et al. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA. 2009;301:1439–50.PubMedCrossRef O’Connor CM, Whellan DJ, Lee KL, et al. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA. 2009;301:1439–50.PubMedCrossRef
8.
go back to reference McMurray JJ, Adamopoulos S, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33:1787–847.PubMedCrossRef McMurray JJ, Adamopoulos S, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33:1787–847.PubMedCrossRef
9.
go back to reference • Arena R, Myers J, Forman DE, et al. Should high-intensity-aerobic interval training become the clinical standard in heart failure? Heart Fail Rev. 2012. Well written and comprehensive review with a detailed section on directions for future research. • Arena R, Myers J, Forman DE, et al. Should high-intensity-aerobic interval training become the clinical standard in heart failure? Heart Fail Rev. 2012. Well written and comprehensive review with a detailed section on directions for future research.
10.
go back to reference Wisloff U, Ellingsen O, Kemi OJ. High-intensity interval training to maximize cardiac benefits of exercise training? Exerc Sport Sci Rev. 2009;37:139–46.PubMedCrossRef Wisloff U, Ellingsen O, Kemi OJ. High-intensity interval training to maximize cardiac benefits of exercise training? Exerc Sport Sci Rev. 2009;37:139–46.PubMedCrossRef
11.
go back to reference Kemi OJ, Wisloff U. High-intensity aerobic exercise training improves the heart in health and disease. J Cardiopulm Rehabil Prev. 2010;30:2–11.PubMed Kemi OJ, Wisloff U. High-intensity aerobic exercise training improves the heart in health and disease. J Cardiopulm Rehabil Prev. 2010;30:2–11.PubMed
12.
go back to reference • Guiraud T, Nigam A, Gremeaux V, et al. High-intensity interval training in cardiac rehabilitation. Sports Med. 2012;42:587–605. Practical review giving a broad perspective of high-intensity interval training in the whole spectrum of patients with cardiovascular diseases.PubMedCrossRef • Guiraud T, Nigam A, Gremeaux V, et al. High-intensity interval training in cardiac rehabilitation. Sports Med. 2012;42:587–605. Practical review giving a broad perspective of high-intensity interval training in the whole spectrum of patients with cardiovascular diseases.PubMedCrossRef
13.
go back to reference Reindell H, Roskamm H. Ein Beitrag zu den physiologischen Grundlagen des Intervalltrainings unter besonderer Berücksichtigung des Kreislaufes. Schweiz Z Sportmed. 1959;7:1–8. Reindell H, Roskamm H. Ein Beitrag zu den physiologischen Grundlagen des Intervalltrainings unter besonderer Berücksichtigung des Kreislaufes. Schweiz Z Sportmed. 1959;7:1–8.
14.
go back to reference Billat LV. Interval training for performance: a scientific and empirical practice. Special recommendations for middle- and long-distance running. Part I: aerobic interval training. Sports Med. 2001;31:13–31.PubMedCrossRef Billat LV. Interval training for performance: a scientific and empirical practice. Special recommendations for middle- and long-distance running. Part I: aerobic interval training. Sports Med. 2001;31:13–31.PubMedCrossRef
15.
go back to reference Meyer K, Lehmann M, Sunder G, et al. Interval versus continuous exercise training after coronary bypass surgery: a comparison of training-induced acute reactions with respect to the effectiveness of the exercise methods. Clin Cardiol. 1990;13:851–61.PubMedCrossRef Meyer K, Lehmann M, Sunder G, et al. Interval versus continuous exercise training after coronary bypass surgery: a comparison of training-induced acute reactions with respect to the effectiveness of the exercise methods. Clin Cardiol. 1990;13:851–61.PubMedCrossRef
16.
go back to reference Meyer K, Schwaibold M, Westbrook S, et al. Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure. Am J Cardiol. 1996;78:1017–22.PubMedCrossRef Meyer K, Schwaibold M, Westbrook S, et al. Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure. Am J Cardiol. 1996;78:1017–22.PubMedCrossRef
17.
go back to reference Wenger HA, Bell GJ. The interactions of intensity, frequency and duration of exercise training in altering cardiorespiratory fitness. Sports Med. 1986;3:346–56.PubMedCrossRef Wenger HA, Bell GJ. The interactions of intensity, frequency and duration of exercise training in altering cardiorespiratory fitness. Sports Med. 1986;3:346–56.PubMedCrossRef
18.
go back to reference Billat VL, Slawinksi J, Bocquet V, et al. Very short (15s–15s) interval-training around the critical velocity allows middle-aged runners to maintain VO2 max for 14 minutes. Int J Sports Med. 2001;22:201–8.PubMedCrossRef Billat VL, Slawinksi J, Bocquet V, et al. Very short (15s–15s) interval-training around the critical velocity allows middle-aged runners to maintain VO2 max for 14 minutes. Int J Sports Med. 2001;22:201–8.PubMedCrossRef
19.
go back to reference Billat VL, Bocquet V, Slawinski J, et al. Effect of a prior intermittent run at vVO2max on oxygen kinetics during an all-out severe run in humans. J Sports Med Phys Fitness. 2000;40:185–94.PubMed Billat VL, Bocquet V, Slawinski J, et al. Effect of a prior intermittent run at vVO2max on oxygen kinetics during an all-out severe run in humans. J Sports Med Phys Fitness. 2000;40:185–94.PubMed
20.
go back to reference Billat VL, Slawinski J, Bocquet V, et al. Intermittent runs at the velocity associated with maximal oxygen uptake enables subjects to remain at maximal oxygen uptake for a longer time than intense but submaximal runs. Eur J Appl Physiol. 2000;81:188–96.PubMedCrossRef Billat VL, Slawinski J, Bocquet V, et al. Intermittent runs at the velocity associated with maximal oxygen uptake enables subjects to remain at maximal oxygen uptake for a longer time than intense but submaximal runs. Eur J Appl Physiol. 2000;81:188–96.PubMedCrossRef
21.
go back to reference Billat LV, Koralsztein JP. Significance of the velocity at VO2max and time to exhaustion at this velocity. Sports Med. 1996;22:90–108.PubMedCrossRef Billat LV, Koralsztein JP. Significance of the velocity at VO2max and time to exhaustion at this velocity. Sports Med. 1996;22:90–108.PubMedCrossRef
22.
go back to reference Dupont G, Blondel N, Lensel G, et al. Critical velocity and time spent at a high level of VO2 for short intermittent runs at supramaximal velocities. Can J Appl Physiol. 2002;27:103–15.PubMedCrossRef Dupont G, Blondel N, Lensel G, et al. Critical velocity and time spent at a high level of VO2 for short intermittent runs at supramaximal velocities. Can J Appl Physiol. 2002;27:103–15.PubMedCrossRef
23.
go back to reference Millet GP, Millet GY, Candau RB. Duration and seriousness of running mechanics alterations after maximal cycling in triathletes. Influence of the performance level. J Sports Med Phys Fitness. 2001;41:147–53.PubMed Millet GP, Millet GY, Candau RB. Duration and seriousness of running mechanics alterations after maximal cycling in triathletes. Influence of the performance level. J Sports Med Phys Fitness. 2001;41:147–53.PubMed
24.
go back to reference Guiraud T, Juneau M, Nigam A, et al. Optimization of high intensity interval exercise in coronary heart disease. Eur J Appl Physiol. 2010;108:733–40.PubMedCrossRef Guiraud T, Juneau M, Nigam A, et al. Optimization of high intensity interval exercise in coronary heart disease. Eur J Appl Physiol. 2010;108:733–40.PubMedCrossRef
25.
go back to reference Guiraud T, Nigam A, Juneau M, et al. Acute responses to high-intensity intermittent exercise in CHD patients. Med Sci Sports Exerc. 2011;43:211–7.PubMed Guiraud T, Nigam A, Juneau M, et al. Acute responses to high-intensity intermittent exercise in CHD patients. Med Sci Sports Exerc. 2011;43:211–7.PubMed
26.
go back to reference Dupont G, Blondel N, Berthoin S. Performance for short intermittent runs: active recovery vs. passive recovery. Eur J Appl Physiol. 2003;89:548–54.PubMedCrossRef Dupont G, Blondel N, Berthoin S. Performance for short intermittent runs: active recovery vs. passive recovery. Eur J Appl Physiol. 2003;89:548–54.PubMedCrossRef
27.
go back to reference Thevenet D, Tardieu M, Zouhal H, et al. Influence of exercise intensity on time spent at high percentage of maximal oxygen uptake during an intermittent session in young endurance-trained athletes. Eur J Appl Physiol. 2007;102:19–26.PubMedCrossRef Thevenet D, Tardieu M, Zouhal H, et al. Influence of exercise intensity on time spent at high percentage of maximal oxygen uptake during an intermittent session in young endurance-trained athletes. Eur J Appl Physiol. 2007;102:19–26.PubMedCrossRef
28.
go back to reference Meyer K, Samek L, Schwaibold M, et al. Physical responses to different modes of interval exercise in patients with chronic heart failure–application to exercise training. Eur Heart J. 1996;17:1040–7.PubMedCrossRef Meyer K, Samek L, Schwaibold M, et al. Physical responses to different modes of interval exercise in patients with chronic heart failure–application to exercise training. Eur Heart J. 1996;17:1040–7.PubMedCrossRef
29.
go back to reference Beale L, Silberbauer J, Guy L, et al. Limitations to high intensity exercise prescription in chronic heart failure patients. Eur J Cardiovasc Nurs. 2011;10:167–73.PubMedCrossRef Beale L, Silberbauer J, Guy L, et al. Limitations to high intensity exercise prescription in chronic heart failure patients. Eur J Cardiovasc Nurs. 2011;10:167–73.PubMedCrossRef
30.
go back to reference Meyer P, Normandin E, Gayda M, et al. High-intensity interval exercise in chronic heart failure: protocol optimization. J Card Fail. 2012;18:126–33.PubMedCrossRef Meyer P, Normandin E, Gayda M, et al. High-intensity interval exercise in chronic heart failure: protocol optimization. J Card Fail. 2012;18:126–33.PubMedCrossRef
31.
go back to reference Meyer P, Guiraud T, Gayda M, et al. High-intensity aerobic interval training in a patient with stable angina pectoris. Am J Phys Med Rehabil. 2010;89:83–6.PubMedCrossRef Meyer P, Guiraud T, Gayda M, et al. High-intensity aerobic interval training in a patient with stable angina pectoris. Am J Phys Med Rehabil. 2010;89:83–6.PubMedCrossRef
32.
go back to reference Wisloff U, Stoylen A, Loennechen JP, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007;115:3086–94.PubMedCrossRef Wisloff U, Stoylen A, Loennechen JP, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation. 2007;115:3086–94.PubMedCrossRef
33.
go back to reference Morton J. Prescribing, quantifying, and monitoring exercise intensity during interval training. Med Sci Sports Exerc. 2007;39:1885. author reply 1886.PubMedCrossRef Morton J. Prescribing, quantifying, and monitoring exercise intensity during interval training. Med Sci Sports Exerc. 2007;39:1885. author reply 1886.PubMedCrossRef
34.
go back to reference Meyer P, Gayda M, Normandin E, et al. High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: A randomized controlled trial evaluating the relationship to endothelial function and inflammation. Am Heart J. 2009;158:734–41. Am Heart J 2010, 159:e21.CrossRef Meyer P, Gayda M, Normandin E, et al. High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: A randomized controlled trial evaluating the relationship to endothelial function and inflammation. Am Heart J. 2009;158:734–41. Am Heart J 2010, 159:e21.CrossRef
35.
go back to reference Meyer K, Samek L, Schwaibold M, et al. Interval training in patients with severe chronic heart failure: analysis and recommendations for exercise procedures. Med Sci Sports Exerc. 1997;29:306–12.PubMedCrossRef Meyer K, Samek L, Schwaibold M, et al. Interval training in patients with severe chronic heart failure: analysis and recommendations for exercise procedures. Med Sci Sports Exerc. 1997;29:306–12.PubMedCrossRef
36.
go back to reference Meyer K, Foster C, Georgakopoulos N, et al. Comparison of left ventricular function during interval versus steady-state exercise training in patients with chronic congestive heart failure. Am J Cardiol. 1998;82:1382–7.PubMedCrossRef Meyer K, Foster C, Georgakopoulos N, et al. Comparison of left ventricular function during interval versus steady-state exercise training in patients with chronic congestive heart failure. Am J Cardiol. 1998;82:1382–7.PubMedCrossRef
37.
go back to reference Foster C, Meyer K, Georgakopoulos N, et al. Left ventricular function during interval and steady state exercise. Med Sci Sports Exerc. 1999;31:1157–62.PubMedCrossRef Foster C, Meyer K, Georgakopoulos N, et al. Left ventricular function during interval and steady state exercise. Med Sci Sports Exerc. 1999;31:1157–62.PubMedCrossRef
38.
go back to reference Tomczak CR, Thompson RB, Paterson I, et al. Effect of acute high-intensity interval exercise on postexercise biventricular function in mild heart failure. J Appl Physiol. 2011;110:398–406.PubMedCrossRef Tomczak CR, Thompson RB, Paterson I, et al. Effect of acute high-intensity interval exercise on postexercise biventricular function in mild heart failure. J Appl Physiol. 2011;110:398–406.PubMedCrossRef
39.
go back to reference Normandin E, Nigam A, Meyer P, et al. Acute responses to intermittent and continuous exercise in heart failure patients. Can J Cardiol. 2012, In press. Normandin E, Nigam A, Meyer P, et al. Acute responses to intermittent and continuous exercise in heart failure patients. Can J Cardiol. 2012, In press.
40.
go back to reference Gayda M, Normandin E, Meyer P, et al. Central hemodynamic responses during acute high-intensity interval exercise and moderate continuous exercise in patients with heart failure. Appl Physiol Nutr Metab. 2012, In press. Gayda M, Normandin E, Meyer P, et al. Central hemodynamic responses during acute high-intensity interval exercise and moderate continuous exercise in patients with heart failure. Appl Physiol Nutr Metab. 2012, In press.
41.
go back to reference Gayda M, Normandin E, Meyer P, et al. Comparison of carbohydrate and lipid oxidation during continuous and intermittent exercise in patients with chronic heart failure. Can J Cardiol. 2012, In press. Gayda M, Normandin E, Meyer P, et al. Comparison of carbohydrate and lipid oxidation during continuous and intermittent exercise in patients with chronic heart failure. Can J Cardiol. 2012, In press.
42.
go back to reference Labrunee M, Guiraud T, Gaucher-Cazalis K, et al. Improvement of ventricular arrhythmias and heart rate variability after a single session of intermittent exercise in chronic heart failure patients. Abstract n° P567. Eur J Cardiovasc Prev Rehabil. 2011;18 Suppl 1:122S. Labrunee M, Guiraud T, Gaucher-Cazalis K, et al. Improvement of ventricular arrhythmias and heart rate variability after a single session of intermittent exercise in chronic heart failure patients. Abstract n° P567. Eur J Cardiovasc Prev Rehabil. 2011;18 Suppl 1:122S.
43.
go back to reference Meyer K, Schwaibold M, Westbrook S, et al. Effects of exercise training and activity restriction on 6-minute walking test performance in patients with chronic heart failure. Am Heart J. 1997;133:447–53.PubMedCrossRef Meyer K, Schwaibold M, Westbrook S, et al. Effects of exercise training and activity restriction on 6-minute walking test performance in patients with chronic heart failure. Am Heart J. 1997;133:447–53.PubMedCrossRef
44.
go back to reference • Smart NA, Steele M. A comparison of 16 weeks of continuous vs intermittent exercise training in chronic heart failure patients. Congestive Heart Failure. 2012;18:205–11. Well designed randomized training study using a moderate intensity in both interval and continuous protocols. Comprehensive outcomes including parameters assessing potential changes in cardiac structure and function and in endothelial function.PubMedCrossRef • Smart NA, Steele M. A comparison of 16 weeks of continuous vs intermittent exercise training in chronic heart failure patients. Congestive Heart Failure. 2012;18:205–11. Well designed randomized training study using a moderate intensity in both interval and continuous protocols. Comprehensive outcomes including parameters assessing potential changes in cardiac structure and function and in endothelial function.PubMedCrossRef
45.
go back to reference Dimopoulos S, Anastasiou-Nana M, Sakellariou D, et al. Effects of exercise rehabilitation program on heart rate recovery in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil. 2006;13:67–73.PubMedCrossRef Dimopoulos S, Anastasiou-Nana M, Sakellariou D, et al. Effects of exercise rehabilitation program on heart rate recovery in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil. 2006;13:67–73.PubMedCrossRef
46.
go back to reference Roditis P, Dimopoulos S, Sakellariou D, et al. The effects of exercise training on the kinetics of oxygen uptake in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil. 2007;14:304–11.PubMedCrossRef Roditis P, Dimopoulos S, Sakellariou D, et al. The effects of exercise training on the kinetics of oxygen uptake in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil. 2007;14:304–11.PubMedCrossRef
47.
go back to reference Freyssin C, Verkindt C, Prieur F, et al. Cardiac rehabilitation in chronic heart failure: effect of an 8-week, high-intensity interval training versus continuous training. Arch Phys Med Rehabil. 2012;93:1359–64.PubMedCrossRef Freyssin C, Verkindt C, Prieur F, et al. Cardiac rehabilitation in chronic heart failure: effect of an 8-week, high-intensity interval training versus continuous training. Arch Phys Med Rehabil. 2012;93:1359–64.PubMedCrossRef
48.
go back to reference Iellamo F, Manzi V, Caminiti G, et al. Matched dose interval and continuous exercise training induce similar cardiorespiratory and metabolic adaptations in patients with heart failure. Int J Cardiol. 2012, In press. Iellamo F, Manzi V, Caminiti G, et al. Matched dose interval and continuous exercise training induce similar cardiorespiratory and metabolic adaptations in patients with heart failure. Int J Cardiol. 2012, In press.
49.
go back to reference • Fu TC, Wang CH, Lin PS, et al. Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure. Int J Cardiol. 2011, In press. Largest randomized trial to date with a substantial number of women. Well designed methods and impressive results in terms of improvement of aerobic capacity compared to continuous exercice. • Fu TC, Wang CH, Lin PS, et al. Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure. Int J Cardiol. 2011, In press. Largest randomized trial to date with a substantial number of women. Well designed methods and impressive results in terms of improvement of aerobic capacity compared to continuous exercice.
50.
go back to reference Anagnostakou V, Chatzimichail K, Dimopoulos S, et al. Effects of interval cycle training with or without strength training on vascular reactivity in heart failure patients. J Card Fail. 2011;17:585–91.PubMedCrossRef Anagnostakou V, Chatzimichail K, Dimopoulos S, et al. Effects of interval cycle training with or without strength training on vascular reactivity in heart failure patients. J Card Fail. 2011;17:585–91.PubMedCrossRef
51.
go back to reference Bouchla A, Karatzanos E, Dimopoulos S, et al. The addition of strength training to aerobic interval training: effects on muscle strength and body composition in CHF patients. J Cardiopulm Rehabil Prev. 2011;31:47–51.PubMed Bouchla A, Karatzanos E, Dimopoulos S, et al. The addition of strength training to aerobic interval training: effects on muscle strength and body composition in CHF patients. J Cardiopulm Rehabil Prev. 2011;31:47–51.PubMed
52.
go back to reference Delagardelle C, Feiereisen P, Autier P, et al. Strength/endurance training versus endurance training in congestive heart failure. Med Sci Sports Exerc. 2002;34:1868–72.PubMedCrossRef Delagardelle C, Feiereisen P, Autier P, et al. Strength/endurance training versus endurance training in congestive heart failure. Med Sci Sports Exerc. 2002;34:1868–72.PubMedCrossRef
53.
go back to reference Tasoulis A, Papazachou O, Dimopoulos S, et al. Effects of interval exercise training on respiratory drive in patients with chronic heart failure. Respir Med. 2010;104:1557–65.PubMedCrossRef Tasoulis A, Papazachou O, Dimopoulos S, et al. Effects of interval exercise training on respiratory drive in patients with chronic heart failure. Respir Med. 2010;104:1557–65.PubMedCrossRef
54.
go back to reference Kemps HM, de Vries WR, Schmikli SL, et al. Assessment of the effects of physical training in patients with chronic heart failure: the utility of effort-independent exercise variables. Eur J Appl Physiol. 2010;108:469–76.PubMedCrossRef Kemps HM, de Vries WR, Schmikli SL, et al. Assessment of the effects of physical training in patients with chronic heart failure: the utility of effort-independent exercise variables. Eur J Appl Physiol. 2010;108:469–76.PubMedCrossRef
55.
go back to reference Nilsson BB, Westheim A, Risberg MA, et al. No effect of group-based aerobic interval training on N-terminal pro-B-type natriuretic peptide levels in patients with chronic heart failure. Scand Cardiovasc J. 2010;44:223–9.PubMedCrossRef Nilsson BB, Westheim A, Risberg MA, et al. No effect of group-based aerobic interval training on N-terminal pro-B-type natriuretic peptide levels in patients with chronic heart failure. Scand Cardiovasc J. 2010;44:223–9.PubMedCrossRef
56.
go back to reference Sabelis LW, Senden PJ, Fijnheer R, et al. Endothelial markers in chronic heart failure: training normalizes exercise-induced vWF release. Eur J Clin Investig. 2004;34:583–9.CrossRef Sabelis LW, Senden PJ, Fijnheer R, et al. Endothelial markers in chronic heart failure: training normalizes exercise-induced vWF release. Eur J Clin Investig. 2004;34:583–9.CrossRef
57.
go back to reference Willenheimer R, Erhardt L, Cline C, et al. Exercise training in heart failure improves quality of life and exercise capacity. Eur Heart J. 1998;19:774–81.PubMedCrossRef Willenheimer R, Erhardt L, Cline C, et al. Exercise training in heart failure improves quality of life and exercise capacity. Eur Heart J. 1998;19:774–81.PubMedCrossRef
58.
go back to reference Smart NA, Dieberg G, Giallauria F. Intermittent versus continuous exercise training in chronic heart failure: A meta-analysis. Int J Cardiol. 2011, In press. Smart NA, Dieberg G, Giallauria F. Intermittent versus continuous exercise training in chronic heart failure: A meta-analysis. Int J Cardiol. 2011, In press.
59.
go back to reference Mancini DM, Eisen H, Kussmaul W, et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation. 1991;83:778–86.PubMedCrossRef Mancini DM, Eisen H, Kussmaul W, et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation. 1991;83:778–86.PubMedCrossRef
60.
go back to reference Rognmo O, Moholdt T, Bakken H, et al. Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation. 2012;126:1436–40.PubMedCrossRef Rognmo O, Moholdt T, Bakken H, et al. Cardiovascular risk of high- versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation. 2012;126:1436–40.PubMedCrossRef
61.
go back to reference Moholdt T, Aamot IL, Granoien I, et al. Long-term follow-up after cardiac rehabilitation A randomized study of usual care exercise training versus aerobic interval training after myocardial infarction. Int J Cardiol. 2011;152:388–90.PubMedCrossRef Moholdt T, Aamot IL, Granoien I, et al. Long-term follow-up after cardiac rehabilitation A randomized study of usual care exercise training versus aerobic interval training after myocardial infarction. Int J Cardiol. 2011;152:388–90.PubMedCrossRef
62.
go back to reference Bartlett JD, Close GL, MacLaren DPM, et al. High-intensity interval running is perceived to be more enjoyable than moderate-intensity continuous exercise: Implications for exercise adherence. J Sports Sci. 2011;29:547–53.PubMedCrossRef Bartlett JD, Close GL, MacLaren DPM, et al. High-intensity interval running is perceived to be more enjoyable than moderate-intensity continuous exercise: Implications for exercise adherence. J Sports Sci. 2011;29:547–53.PubMedCrossRef
63.
go back to reference Stoylen A, Conraads V, Halle M, et al. Controlled study of myocardial recovery after interval training in heart failure: SMARTEX-HF–rationale and design. Eur J Prev Cardiol. 2012;19:813–21.PubMedCrossRef Stoylen A, Conraads V, Halle M, et al. Controlled study of myocardial recovery after interval training in heart failure: SMARTEX-HF–rationale and design. Eur J Prev Cardiol. 2012;19:813–21.PubMedCrossRef
64.
go back to reference • Piepoli MF, Conraads V, Corra U, et al. Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail. 2011;13:347–57. Position statement with practical recommendations for exercise prescription including high intensity interval exercise. Update on the pathophysiology of exercise intolerance and review of the literature on exercise training in heart failure in an online appendix.PubMedCrossRef • Piepoli MF, Conraads V, Corra U, et al. Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail. 2011;13:347–57. Position statement with practical recommendations for exercise prescription including high intensity interval exercise. Update on the pathophysiology of exercise intolerance and review of the literature on exercise training in heart failure in an online appendix.PubMedCrossRef
Metadata
Title
High-Intensity Aerobic Interval Exercise in Chronic Heart Failure
Authors
Philippe Meyer
Mathieu Gayda
Martin Juneau
Anil Nigam
Publication date
01-06-2013
Publisher
Current Science Inc.
Published in
Current Heart Failure Reports / Issue 2/2013
Print ISSN: 1546-9530
Electronic ISSN: 1546-9549
DOI
https://doi.org/10.1007/s11897-013-0130-3

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Management of Heart Failure (TE Meyer, Section Editor)

Current Status of Cell-Based Therapy for Heart Failure

Pathophysiology: Neuroendocrine, Vascular, and Metabolic Factors (SD Katz, Section Editor)

Chemohypersensitivity and Autonomic Modulation of Venous Capacitance in the Pathophysiology of Acute Decompensated Heart Failure

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.