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Published in: Current Diabetes Reports 7/2014

01-07-2014 | Macrovascular Complications in Diabetes (L Perreault, Section Editor)

Metabolic Consequences of Sleep and Circadian Disorders

Authors: Christopher M. Depner, Ellen R. Stothard, Kenneth P. Wright Jr.

Published in: Current Diabetes Reports | Issue 7/2014

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Abstract

Sleep and circadian rhythms modulate or control daily physiological patterns with importance for normal metabolic health. Sleep deficiencies associated with insufficient sleep schedules, insomnia with short-sleep duration, sleep apnea, narcolepsy, circadian misalignment, shift work, night eating syndrome, and sleep-related eating disorder may all contribute to metabolic dysregulation. Sleep deficiencies and circadian disruption associated with metabolic dysregulation may contribute to weight gain, obesity, and type 2 diabetes potentially by altering timing and amount of food intake, disrupting energy balance, inflammation, impairing glucose tolerance, and insulin sensitivity. Given the rapidly increasing prevalence of metabolic diseases, it is important to recognize the role of sleep and circadian disruption in the development, progression, and morbidity of metabolic disease. Some findings indicate sleep treatments and countermeasures improve metabolic health, but future clinical research investigating prevention and treatment of chronic metabolic disorders through treatment of sleep and circadian disruption is needed.
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Metadata
Title
Metabolic Consequences of Sleep and Circadian Disorders
Authors
Christopher M. Depner
Ellen R. Stothard
Kenneth P. Wright Jr.
Publication date
01-07-2014
Publisher
Springer US
Published in
Current Diabetes Reports / Issue 7/2014
Print ISSN: 1534-4827
Electronic ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-014-0507-z

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