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Published in: Current Atherosclerosis Reports 1/2016

01-01-2016 | Coronary Heart Disease (S. Virani and S. Naderi, Section Editors)

The Link Between Obstructive Sleep Apnea and Cardiovascular Disease

Authors: Fré Bauters, Ernst R. Rietzschel, Katrien B. C. Hertegonne, Julio A. Chirinos

Published in: Current Atherosclerosis Reports | Issue 1/2016

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Abstract

Obstructive sleep apnea (OSA) is common in the general population and highly prevalent in patients with cardiovascular disease. In this paper, we review (1) the pathophysiological mechanisms of OSA that may causally contribute to cardiovascular disease; (2) current evidence regarding the association between OSA and hypertension, stroke, ischemic heart disease, heart failure, atrial fibrillation, and cardiovascular mortality; and (3) the impact of continuous positive airway pressure (CPAP) treatment on cardiovascular risk factors and outcomes. We emphasize the importance of obesity as a comorbidity of OSA and a confounder in the association between OSA and cardiovascular disease. We also discuss the importance of addressing obesity in patients with OSA, as a strategy to reduce the burden of cardiovascular risk factors in this population. Implications for the approach of patients’ OSA in clinical practice and future research directions are discussed.
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Metadata
Title
The Link Between Obstructive Sleep Apnea and Cardiovascular Disease
Authors
Fré Bauters
Ernst R. Rietzschel
Katrien B. C. Hertegonne
Julio A. Chirinos
Publication date
01-01-2016
Publisher
Springer US
Published in
Current Atherosclerosis Reports / Issue 1/2016
Print ISSN: 1523-3804
Electronic ISSN: 1534-6242
DOI
https://doi.org/10.1007/s11883-015-0556-z

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