Skip to main content
Top
Published in: Obesity Surgery 7/2016

01-07-2016 | Review Article

Revision of Roux-En-Y Gastric Bypass for Weight Regain: a Systematic Review of Techniques and Outcomes

Authors: Daniel D. Tran, Ifeanyi D. Nwokeabia, Stephanie Purnell, Syed Nabeel Zafar, Gezzer Ortega, Kakra Hughes, Terrence M. Fullum

Published in: Obesity Surgery | Issue 7/2016

Login to get access

Abstract

Background

Weight regain has led to an increase in revision of Roux-en-Y gastric bypass (RYGB) surgeries. There is no standardized approach to revisional surgery after failed RYGB. We performed an exhaustive literature search to elucidate surgical revision options. Our objective was to evaluate outcomes and complications of various methods of revision after RYGB to identify the option with the best outcomes for failed primary RYGB.

Method

A systematic literature search was conducted using the following search tools and databases: PubMed, Google Scholar, Cochrane Clinical Trials Database, Cochrane Review Database, EMBASE, and Allied and Complementary Medicine to identify all relevant studies describing revision after failed RYGB. Inclusion criteria comprised of revisional surgery for weight gain after RYGB.

Results

Of the 1200 articles found, only 799 were selected for our study. Of the 799, 24 studies, with a total of 866 patients, were included for a systematic review. Of the 24 studies, 5 were conversion to Distal Roux-en-y gastric bypass (DRYGB), 5 were revision of gastric pouch and anastomosis, 6 were revision with gastric band, 2 were revision to biliopancreatic diversion/duodenal switch (BPD/DS), and 6 were revision to endoluminal procedures (i.e., stomaphyx). Mean percent excess body mass index loss (%EBMIL) after revision up to 1 and 3-year follow-up for BPD/DS was 63.7 and 76 %, DRYGB was 54 and 52.2 %, gastric banding revision 47.6 and 47.3 %, gastric pouch/anastomosis revision 43.3 and 14 %, and endoluminal procedures at 32.1 %, respectively. Gastric pouch/anastomosis revision resulted in the lowest major complication rate at 3.5 % and DRYGB with the highest at 11.9 % when compared to the other revisional procedures. The mortality rate was 0.6 % which only occurred in the DRYGB group.

Conclusion

All 866 patients in the 24 studies reported significant early initial weight loss after revision for failed RYGB. However, of the five surgical revision options considered, BPD/DS, DRYGB, and gastric banding resulted in sustained weight loss, with acceptable complication rate.
Literature
1.
2.
go back to reference McTigue K, Harris R, Hemphill B, et al. Screening and interventions for obesity in adults: summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2003;139(11):933–49.CrossRefPubMed McTigue K, Harris R, Hemphill B, et al. Screening and interventions for obesity in adults: summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2003;139(11):933–49.CrossRefPubMed
3.
go back to reference Colquitt J, Picot J, Loveman E, Clegg A. Surgery for obesity. Cochrane Database Syst Rev. 2009;2:CD003641.PubMed Colquitt J, Picot J, Loveman E, Clegg A. Surgery for obesity. Cochrane Database Syst Rev. 2009;2:CD003641.PubMed
4.
go back to reference Glenny A, O’Meara S, Melville A, Sheldon T, Wilson C. The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord. 1997;21(9):715–37.CrossRefPubMed Glenny A, O’Meara S, Melville A, Sheldon T, Wilson C. The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord. 1997;21(9):715–37.CrossRefPubMed
5.
go back to reference Santry H, Gillen D, Lauderdale D. Trends in bariatric surgical procedures. JAMA. 2005;294(15):1909–17.CrossRefPubMed Santry H, Gillen D, Lauderdale D. Trends in bariatric surgical procedures. JAMA. 2005;294(15):1909–17.CrossRefPubMed
6.
7.
go back to reference Austrheim-Smith I, Brethauer S, Rogula T, Wolfe B. Evolution of bariatric minimally invasive surgery. In: Schauer P, Schirmer B, Brethauer S, eds. Minimally invasive bariatric surgery. 2007:17. Austrheim-Smith I, Brethauer S, Rogula T, Wolfe B. Evolution of bariatric minimally invasive surgery. In: Schauer P, Schirmer B, Brethauer S, eds. Minimally invasive bariatric surgery. 2007:17.
8.
go back to reference Elder K, Wolfe B. Bariatric surgery: a review of procedures and outcomes. Gastroenterology. 2007;132(6):2253–71.CrossRefPubMed Elder K, Wolfe B. Bariatric surgery: a review of procedures and outcomes. Gastroenterology. 2007;132(6):2253–71.CrossRefPubMed
9.
go back to reference Lim C, Liew V, Talbot M, Jorgensen J, Loi K. Revisional bariatric surgery. Obes Surg. 2009;19(7):827–32.CrossRefPubMed Lim C, Liew V, Talbot M, Jorgensen J, Loi K. Revisional bariatric surgery. Obes Surg. 2009;19(7):827–32.CrossRefPubMed
10.
go back to reference Kalarchian M, Marcus M, Wilson G, Labouvie E, Brolin R, LaMarca L. Binge eating among gastric bypass patients at long-term follow-up. Obes Surg. 2012;12(2):270–5.CrossRef Kalarchian M, Marcus M, Wilson G, Labouvie E, Brolin R, LaMarca L. Binge eating among gastric bypass patients at long-term follow-up. Obes Surg. 2012;12(2):270–5.CrossRef
11.
go back to reference Horgan S, Jacobsen G, Weiss G, Oldham J, Denk P, Borao F, et al. Incisionless revision of post-Roux-en-Y bypass stomal and pouch dilation: multicenter registry results. Surg Obes Relat Dis. 2010;6(3):290–5.CrossRefPubMed Horgan S, Jacobsen G, Weiss G, Oldham J, Denk P, Borao F, et al. Incisionless revision of post-Roux-en-Y bypass stomal and pouch dilation: multicenter registry results. Surg Obes Relat Dis. 2010;6(3):290–5.CrossRefPubMed
12.
go back to reference Topart P, Becouarn G, Ritz P. Biliopancreatic diversion with duodenal switch or gastric bypass for failed gastric banding: retrospective study from two institutions with preliminary results. Surg Obes Relat Dis. 2007;3(5):521–5.CrossRefPubMed Topart P, Becouarn G, Ritz P. Biliopancreatic diversion with duodenal switch or gastric bypass for failed gastric banding: retrospective study from two institutions with preliminary results. Surg Obes Relat Dis. 2007;3(5):521–5.CrossRefPubMed
13.
go back to reference Behrns K, Smith C, Kelly K, Sarr M. Re-operative bariatric surgery: lessons learned to improve patient selection and results. Ann Surg. 1993;218(5):646–53.CrossRefPubMedPubMedCentral Behrns K, Smith C, Kelly K, Sarr M. Re-operative bariatric surgery: lessons learned to improve patient selection and results. Ann Surg. 1993;218(5):646–53.CrossRefPubMedPubMedCentral
14.
go back to reference Sanchez H, Cabrera A, Cabrera K, Zerrweck C, Mosti M, Sierra M, et al. Laparoscopic Roux-en-Y gastric bypass as a revision procedure after restrictive bariatric surgery. Obes Surg. 2008;18(12):1539–43.CrossRefPubMed Sanchez H, Cabrera A, Cabrera K, Zerrweck C, Mosti M, Sierra M, et al. Laparoscopic Roux-en-Y gastric bypass as a revision procedure after restrictive bariatric surgery. Obes Surg. 2008;18(12):1539–43.CrossRefPubMed
15.
go back to reference Kyzer S, Raziel A, Landau O, Matz A, Charuzi I. Use of adjustable silicone gastric banding for revision of failed gastric bariatric operations. Obes Surg. 2001;11(1):66–9.CrossRefPubMed Kyzer S, Raziel A, Landau O, Matz A, Charuzi I. Use of adjustable silicone gastric banding for revision of failed gastric bariatric operations. Obes Surg. 2001;11(1):66–9.CrossRefPubMed
16.
go back to reference Bessler M, Daud A, Digiorgi M, Inabnet W, Schrope B, Olivero-Rivera L, et al. Adjustable gastric banding as a revisional bariatric procedure after failed gastric bypass-intermediate results. Surg Obes Relat Dis. 2010;6(2010):31–5.CrossRefPubMed Bessler M, Daud A, Digiorgi M, Inabnet W, Schrope B, Olivero-Rivera L, et al. Adjustable gastric banding as a revisional bariatric procedure after failed gastric bypass-intermediate results. Surg Obes Relat Dis. 2010;6(2010):31–5.CrossRefPubMed
17.
go back to reference Irani K, Youn H, Ren-Fielding C, Fielding G, Kurian M. Midterm results for gastric banding as salvage procedure for patients with weight loss failure after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2011;7(2):219–24.CrossRefPubMed Irani K, Youn H, Ren-Fielding C, Fielding G, Kurian M. Midterm results for gastric banding as salvage procedure for patients with weight loss failure after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2011;7(2):219–24.CrossRefPubMed
18.
go back to reference Dapri G, Cadière G, Himpens J. Laparoscopic placement of non-adjustable silicone ring for weight regain after Roux-en-Y gastric bypass. Obes Surg. 2009;19(5):650–4.CrossRefPubMed Dapri G, Cadière G, Himpens J. Laparoscopic placement of non-adjustable silicone ring for weight regain after Roux-en-Y gastric bypass. Obes Surg. 2009;19(5):650–4.CrossRefPubMed
19.
go back to reference Chin P, Ali M, Francis K, Leport P. Adjustable gastric band placed around gastric bypass pouch as revision operation for failed gastric bypass. Surg Obes Relat Dis. 2009;5(1):38–42.CrossRefPubMed Chin P, Ali M, Francis K, Leport P. Adjustable gastric band placed around gastric bypass pouch as revision operation for failed gastric bypass. Surg Obes Relat Dis. 2009;5(1):38–42.CrossRefPubMed
20.
go back to reference Jirapinyo P, Slattery J, Ryan M, Dayyeh B, Lautz D, Thompson C. Evaluation of an endoscopic suturing device for transoral outlet reduction in patients with weight regain following Roux-en-Y gastric bypass. Endoscopy. 2013;45(7):532–6.CrossRefPubMed Jirapinyo P, Slattery J, Ryan M, Dayyeh B, Lautz D, Thompson C. Evaluation of an endoscopic suturing device for transoral outlet reduction in patients with weight regain following Roux-en-Y gastric bypass. Endoscopy. 2013;45(7):532–6.CrossRefPubMed
21.
go back to reference Raman S, Holover S, Garber S. Endolumenal revision obesity surgery results in weight loss and closure of gastric-gastric fistula. Surg Obes Relat Dis. 2011;7(3):304–8.CrossRefPubMed Raman S, Holover S, Garber S. Endolumenal revision obesity surgery results in weight loss and closure of gastric-gastric fistula. Surg Obes Relat Dis. 2011;7(3):304–8.CrossRefPubMed
22.
go back to reference Ryou M, Mullady D, Lautz D, Thompson C. Pilot study evaluating technical feasibility and early outcomes of second-generation endosurgical platform for treatment of weight regain after gastric bypass surgery. Surg Obes Relat Dis. 2009;5(4):450–4.CrossRefPubMed Ryou M, Mullady D, Lautz D, Thompson C. Pilot study evaluating technical feasibility and early outcomes of second-generation endosurgical platform for treatment of weight regain after gastric bypass surgery. Surg Obes Relat Dis. 2009;5(4):450–4.CrossRefPubMed
23.
go back to reference Abu B, Jirapinyo P, Weitzner Z, Barker C, Flicker M, Lautz D, et al. Endoscopic sclerotherapy for the treatment of weight regain after Roux-en-Y gastric bypass: outcomes, complications, and predictors of response in 575 procedures. Gastrointest Endosc. 2012;76(2):275–82.CrossRef Abu B, Jirapinyo P, Weitzner Z, Barker C, Flicker M, Lautz D, et al. Endoscopic sclerotherapy for the treatment of weight regain after Roux-en-Y gastric bypass: outcomes, complications, and predictors of response in 575 procedures. Gastrointest Endosc. 2012;76(2):275–82.CrossRef
24.
go back to reference Tran D, Ong’uti S, Ortega G, Onwugbufor M, Ivey G, Fullum T. Effective weight loss management with endoscopic gastric plication using StomaphyX device: is it achievable? Surg Obes Relat Dis. 2013;9(1):113–7.CrossRefPubMed Tran D, Ong’uti S, Ortega G, Onwugbufor M, Ivey G, Fullum T. Effective weight loss management with endoscopic gastric plication using StomaphyX device: is it achievable? Surg Obes Relat Dis. 2013;9(1):113–7.CrossRefPubMed
25.
go back to reference Scopinaro N, Gianetta E, Adami GF, et al. Biliopancreatic diversion for obesity at eighteen years. Surgery. 1996;119(3):261–8.CrossRefPubMed Scopinaro N, Gianetta E, Adami GF, et al. Biliopancreatic diversion for obesity at eighteen years. Surgery. 1996;119(3):261–8.CrossRefPubMed
26.
go back to reference Parikh M, Pomp A, Gagner M. Laparoscopic conversion of failed gastric bypass to duodenal switch: technical considerations and preliminary outcomes. Surg Obes Relat Dis. 2007;3(6):611–8.CrossRefPubMed Parikh M, Pomp A, Gagner M. Laparoscopic conversion of failed gastric bypass to duodenal switch: technical considerations and preliminary outcomes. Surg Obes Relat Dis. 2007;3(6):611–8.CrossRefPubMed
27.
go back to reference Keshishian A, Zahriya K, Hartoonian T, Ayagian C. Duodenal switch is a safe operation for patients who have failed other bariatric operations. Obes Surg. 2004;14(9):1187–92.CrossRefPubMed Keshishian A, Zahriya K, Hartoonian T, Ayagian C. Duodenal switch is a safe operation for patients who have failed other bariatric operations. Obes Surg. 2004;14(9):1187–92.CrossRefPubMed
28.
go back to reference Morales M, Wheeler A, Ramaswamy A, Scott J, Torre R. Laparoscopic revisional surgery after Roux-en-Y gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis. 2010;6(5):485–90.CrossRefPubMed Morales M, Wheeler A, Ramaswamy A, Scott J, Torre R. Laparoscopic revisional surgery after Roux-en-Y gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis. 2010;6(5):485–90.CrossRefPubMed
29.
go back to reference Iannelli A, Schneck A, Hébuterne X, Gugenheim J. Gastric pouch resizing for Roux-en-Y gastric bypass failure in patients with a dilated pouch. Surg Obes Relat Dis. 2013;9(2):260–7.CrossRefPubMed Iannelli A, Schneck A, Hébuterne X, Gugenheim J. Gastric pouch resizing for Roux-en-Y gastric bypass failure in patients with a dilated pouch. Surg Obes Relat Dis. 2013;9(2):260–7.CrossRefPubMed
30.
go back to reference Parikh M, Heacock L, Gagner M. Laparoscopic “gastrojejunal sleeve reduction” as a revision procedure for weight loss failure after Roux-en-Y gastric bypass. Obes Surg. 2011;21(5):650–4.CrossRefPubMed Parikh M, Heacock L, Gagner M. Laparoscopic “gastrojejunal sleeve reduction” as a revision procedure for weight loss failure after Roux-en-Y gastric bypass. Obes Surg. 2011;21(5):650–4.CrossRefPubMed
31.
go back to reference Tran D, Hamdi A, Julien C, Brown P, Woods I, Hamdi A, et al. Midterm outcomes of revisional surgery for gastric pouch and gastrojejunal anastomotic enlargement in patients with weight regain after gastric bypass for morbid obesity. Obes Surg. 2014;24(8):1386–90.CrossRefPubMed Tran D, Hamdi A, Julien C, Brown P, Woods I, Hamdi A, et al. Midterm outcomes of revisional surgery for gastric pouch and gastrojejunal anastomotic enlargement in patients with weight regain after gastric bypass for morbid obesity. Obes Surg. 2014;24(8):1386–90.CrossRefPubMed
32.
go back to reference Fobi M, Lee H, Igwe D, Felahy B, James E, Stanczyk M, et al. Revision of failed gastric bypass to distal Roux-en-Y gastric bypass: a review of 65 cases. Obes Surg. 2001;11(2):190–5.CrossRefPubMed Fobi M, Lee H, Igwe D, Felahy B, James E, Stanczyk M, et al. Revision of failed gastric bypass to distal Roux-en-Y gastric bypass: a review of 65 cases. Obes Surg. 2001;11(2):190–5.CrossRefPubMed
33.
go back to reference Rawlins M, Teel D, Hedgcorth K, Maguire J. Revision of Roux-en-Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. 2011;7(1):45–9.CrossRefPubMed Rawlins M, Teel D, Hedgcorth K, Maguire J. Revision of Roux-en-Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. 2011;7(1):45–9.CrossRefPubMed
34.
go back to reference Torres J. Why I prefer gastric bypass distal Roux-en-Y gastroileostomy. Obes Surg. 1991;1(2):189–94.CrossRefPubMed Torres J. Why I prefer gastric bypass distal Roux-en-Y gastroileostomy. Obes Surg. 1991;1(2):189–94.CrossRefPubMed
35.
go back to reference Srikanth M, Oh K, Fox S. Revision to malabsorption Roux-en-Y gastric bypass (MRNYGBP) provides long-term (10 years) durable weight loss in patients with failed anatomically intact gastric restrictive operations. Obes Surg. 2011;21:825–31.CrossRefPubMed Srikanth M, Oh K, Fox S. Revision to malabsorption Roux-en-Y gastric bypass (MRNYGBP) provides long-term (10 years) durable weight loss in patients with failed anatomically intact gastric restrictive operations. Obes Surg. 2011;21:825–31.CrossRefPubMed
36.
go back to reference Fox S, Fox K, Oh K. The gastric bypass for failed bariatric surgical procedures. Obes Surg. 1996;6:145–50.CrossRefPubMed Fox S, Fox K, Oh K. The gastric bypass for failed bariatric surgical procedures. Obes Surg. 1996;6:145–50.CrossRefPubMed
37.
go back to reference Sugerman H, Kellum J, Demaria E. Conversion of proximal to distal gastric bypass for failed gastric bypass for superobesity. J Gastrointest Surg. 1997;1:517–25.CrossRefPubMed Sugerman H, Kellum J, Demaria E. Conversion of proximal to distal gastric bypass for failed gastric bypass for superobesity. J Gastrointest Surg. 1997;1:517–25.CrossRefPubMed
38.
go back to reference Brolin R, Cody RP. Adding malabsorption for weight loss failure after gastric bypass. Surg Endosc. 2007;21:1924–6.CrossRefPubMed Brolin R, Cody RP. Adding malabsorption for weight loss failure after gastric bypass. Surg Endosc. 2007;21:1924–6.CrossRefPubMed
39.
go back to reference Brolin R, Cody R. Weight loss outcome of revisional bariatric operations varies according to the primary procedure. Ann Surg. 2008;248:227–32.CrossRefPubMed Brolin R, Cody R. Weight loss outcome of revisional bariatric operations varies according to the primary procedure. Ann Surg. 2008;248:227–32.CrossRefPubMed
40.
go back to reference Dapri G, Cadière G, Himpens J. Laparoscopic conversion of Roux-en-Y gastric bypass to distal gastric bypass for weight regain. J Laparoendosc Adv Surg Tech. 2011;21(1):19–23.CrossRef Dapri G, Cadière G, Himpens J. Laparoscopic conversion of Roux-en-Y gastric bypass to distal gastric bypass for weight regain. J Laparoendosc Adv Surg Tech. 2011;21(1):19–23.CrossRef
41.
go back to reference Kellum J, Chikunguwo S, Maher J, Wolfe L, Sugerman H. Long-term results of malabsorptive distal Roux-en-Y gastric bypass in superobese patients. Surg Obes Relat Dis. 2011;7:189–94.CrossRefPubMed Kellum J, Chikunguwo S, Maher J, Wolfe L, Sugerman H. Long-term results of malabsorptive distal Roux-en-Y gastric bypass in superobese patients. Surg Obes Relat Dis. 2011;7:189–94.CrossRefPubMed
42.
go back to reference Brolin R, LaMarca L, Kenler H, Cody R. Malabsorptive gastric bypass in patients with superobesity. J Gastrointest Surg. 2002;6:195–205.CrossRefPubMed Brolin R, LaMarca L, Kenler H, Cody R. Malabsorptive gastric bypass in patients with superobesity. J Gastrointest Surg. 2002;6:195–205.CrossRefPubMed
Metadata
Title
Revision of Roux-En-Y Gastric Bypass for Weight Regain: a Systematic Review of Techniques and Outcomes
Authors
Daniel D. Tran
Ifeanyi D. Nwokeabia
Stephanie Purnell
Syed Nabeel Zafar
Gezzer Ortega
Kakra Hughes
Terrence M. Fullum
Publication date
01-07-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 7/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-016-2201-5

Other articles of this Issue 7/2016

Obesity Surgery 7/2016 Go to the issue