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Obesity Surgery
Published in: Obesity Surgery 2/2008

01-02-2008 | Research Article

Vitamin D and the Bariatric Surgical Patient: A Review

Authors: Charlene W. Compher, Karen O. Badellino, Joseph I. Boullata

Published in: Obesity Surgery | Issue 2/2008

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Abstract

Objective

Adiposity has been inversely associated with vitamin D concentration across a range of body mass index values and cultural groups. As obesity has increased markedly worldwide, a greater number of patients with severe obesity have been treated with gastric restrictive and/or malabsorptive surgical procedures. The purpose of this review was to describe current knowledge about vitamin D and severe obesity, and the impact of obesity surgery on vitamin D status.

Research Methods and Procedures

A systematic review was conducted with search terms obesity, vitamin D, osteoporosis, bone disease, gastric bypass, and obesity surgery in various combinations. Publications were limited to those since 2000 to control for similarity in vitamin D assays and obesity prevalence levels.

Results

Mean 25-hydroxy vitamin D was <80 nmol/l in more than 1,900 patients preoperatively, and was not restored to the optimal concentration of >80 nmol/l postoperatively. Both secondary hyperparathyroidism and bone loss were common, particularly when the obesity surgery included a malabsorptive component. Standard postsurgical supplementation with vitamin D and calcium have not been adequate to suppress secondary hyperparathyroidism or to restore 25-hydroxy vitamin D status.

Discussion

The mechanisms behind vitamin D deficiency in severe obesity and evidence-based corrective actions have not been well-defined. Of particular concern are adolescents who qualify for and elect surgical treatment of their obesity, where subsequent metabolic bone disease may be long-standing.
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Metadata
Title
Vitamin D and the Bariatric Surgical Patient: A Review
Authors
Charlene W. Compher
Karen O. Badellino
Joseph I. Boullata
Publication date
01-02-2008
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 2/2008
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-007-9289-6

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