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Archives of Osteoporosis

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01-12-2020 | Bisphosphonate | Review

A case of pregnancy and lactation-associated osteoporosis and a review of the literature

Authors: Pu Jia, RuiDeng Wang, Jing Yuan, Hao Chen, Li Bao, Fei Feng, Hai Tang

Published in: Archives of Osteoporosis | Issue 1/2020

Abstract

Introduction

The pregnancy and lactation-associated osteoporosis (PLO) is a rare disease whose precise pathophysiological mechanisms remain mostly unknown.

Case report

We reported here a case of PLO that occurred in the early postpartum period and led to multiple compression fractures. Combination therapy with alendronate, calcium carbonate, and vitamin D was used to treat the patient and a marked but gradual increase in the density of bone mineral was observed. Moreover, no further fractures have occurred.

Conclusion

PLO is a very rare type of osteoporosis associated with severe chronic back pain. Increased bone resorption significantly increases the risk of bone fractures in women with PLO. Early diagnosis, stopping breastfeeding, treatment of calcium and vitamin D, bisphosphonates, or other antiosteoporosis medicine and regular follow-ups of these cases are particularly important in the prevention of fractures and to increase the quality of life of patients.

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Title: A case of pregnancy and lactation-associated osteoporosis and a review of the literature
Authors: Pu Jia
RuiDeng Wang
Jing Yuan
Hao Chen
Li Bao
Fei Feng
Hai Tang
Publication date: 01-12-2020
Publisher: Springer London
Keywords: Bisphosphonate
Lactation
Osteoporosis
Osteoporosis
Back Pain
Back Pain
Back Pain
Published in: Archives of Osteoporosis / Issue 1/2020
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-020-00768-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A case of pregnancy and lactation-associated osteoporosis and a review of the literature

Abstract

Introduction

Case report

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case report

Conclusion

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