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Published in: Journal of General Internal Medicine 12/2012

01-12-2012 | Original Research

“Stealth” Alerts to Improve Warfarin Monitoring When Initiating Interacting Medications

Authors: Kate E. Koplan, MD, MPH, Alan D. Brush, MD, Marvin S. Packer, MD, Fang Zhang, PhD, Margaret D. Senese, BS, Steven R. Simon, MD, MPH

Published in: Journal of General Internal Medicine | Issue 12/2012

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ABSTRACT

BACKGROUND

As electronic health records (EHRs) become widely adopted, alerts and reminders can improve medication safety, but excessive alerts may irritate or overwhelm clinicians, thereby reducing their effectiveness. We developed a novel “stealth” alert in an EHR to improve anticoagulation monitoring for patients prescribed a medication that could interact with warfarin. Instead of alerting the prescribing provider, the system notified a multidisciplinary anticoagulation management service, so that the prescribing clinicians never saw the alerts. We aimed to determine whether these “stealth” alerts increased the frequency of anticoagulation monitoring following the co-prescription of warfarin and a potentially interacting medication.

METHODS

We conducted a pre-post intervention study, analyzed using an interrupted time-series, within a large, multispecialty group practice that uses a common EHR. The study included a 12-month period preceding the intervention, a 2-month period during intervention implementation, and a 6-month post-intervention period. The primary outcome measure was the proportion of patients completing anticoagulation monitoring within 5 days of a new co-prescribing event.

RESULTS

Prior to implementation of the stealth alert, 34 % of patients completed anticoagulation monitoring within 5 days after the prescription of a medication with a potential warfarin interaction. After implementation of the alert, 39 % completed testing within 5 days (odds ratio 1.24, 95 % confidence interval 1.12–1.37).

CONCLUSIONS

Stealth alerts increased the proportion of patients who underwent anticoagulation monitoring following the prescription of a medication that could potentially interact with warfarin. This team-based approach to clinical-decision support directs alerts away from prescribing clinicians and toward individuals who can directly implement them.
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Metadata
Title
“Stealth” Alerts to Improve Warfarin Monitoring When Initiating Interacting Medications
Authors
Kate E. Koplan, MD, MPH
Alan D. Brush, MD
Marvin S. Packer, MD
Fang Zhang, PhD
Margaret D. Senese, BS
Steven R. Simon, MD, MPH
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 12/2012
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-012-2137-y

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