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Journal of General Internal Medicine
Published in: Journal of General Internal Medicine 10/2010

01-10-2010 | Reviews

Physician Effectiveness in Interventions to Improve Cardiovascular Medication Adherence: A Systematic Review

Authors: Sarah L. Cutrona, MD, MPH, Niteesh K. Choudhry, MD, PhD, Margaret Stedman, PhD, Amber Servi, BA, Joshua N. Liberman, PhD, Troyen Brennan, MD, JD, Michael A. Fischer, MD, MPH, M. Alan Brookhart, PhD, William H. Shrank, MD, MSHS

Published in: Journal of General Internal Medicine | Issue 10/2010

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Abstract

BACKGROUND

Medications for the prevention and treatment of cardiovascular disease save lives but adherence is often inadequate. The optimal role for physicians in improving adherence remains unclear.

OBJECTIVE

Using existing evidence, we set the goal of evaluating the physician’s role in improving medication adherence.

DESIGN

We conducted systematic searches of English-language peer-reviewed publications in MEDLINE and EMBASE from 1966 through 12/31/2008.

SUBJECTS AND INTERVENTIONS

We selected randomized controlled trials of interventions to improve adherence to medications used for preventing or treating cardiovascular disease or diabetes.

MAIN MEASURES

Articles were classified as either (1) physician “active”—a physician participated in designing or implementing the intervention; (2) physician “passive”—physicians treating intervention group patients received patient adherence information while physicians treating controls did not; or (3) physicians noninvolved. We also identified studies in which healthcare professionals helped deliver the intervention. We did a meta-analysis of the studies involving healthcare professionals to determine aggregate Cohen’s D effect sizes (ES).

KEY RESULTS

We identified 6,550 articles; 168 were reviewed in full, 82 met inclusion criteria. The majority of all studies (88.9%) showed improved adherence. Physician noninvolved studies were more likely (35.0% of studies) to show a medium or large effect on adherence compared to physician-involved studies (31.3%). Among interventions requiring a healthcare professional, physician-noninvolved interventions were more effective (ES 0.47; 95% CI 0.38–0.56) than physician-involved interventions (ES 0.25; 95% CI 0.21–0.29; p < 0.001). Among physician-involved interventions, physician-passive interventions were marginally more effective (ES 0.29; 95% CI 0.22–0.36) than physician-active interventions (ES 0.23; 95% CI 0.17–0.28; p = 0.2).

CONCLUSIONS

Adherence interventions utilizing non-physician healthcare professionals are effective in improving cardiovascular medication adherence, but further study is needed to identify the optimal role for physicians.
Appendix
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Literature
1.
World Health Organization. Adherence to long-term therapies: evidence for action. Geneva, Switzerland: WHO; 2003.
2.
Avorn J, Monette J, Lacour A, et al. Persistence of use of lipid-lowering medications: a cross-national study. JAMA. 1998;279(18):1458–62.CrossRefPubMed
3.
Stuart BC, Simoni-Wastila L, Zhao L, Lloyd JT, JA D. Increased persistency in medication use by U.S. Medicare beneficiaries with diabetes is associated with lower hospitalization rates and cost savings. Diab Care. 2009;32(4):647–9.CrossRef
4.
Rasmussen JN, Chong A, Alter DA. Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction. JAMA. 2007;297(2):177–86.CrossRefPubMed
5.
6.
Kripalani S, Yao X, Haynes RB. Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med. 2007;167(6):540–50.CrossRefPubMed
7.
Haynes RB, Ackloo E, Sahota N, McDonald HP, Yao X. Interventions for enhancing medication adherence. Cochrane Database Syst Rev. 2008(2):CD000011.
8.
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106(25):3143–3421.
9.
Cohen J. Statistical power analysis for the behavioral sciences. New York: Lawrence Erlbaum associates; 1988.
10.
Dunlap W, Cortina J, Vaslow J, Burke M. Meta-analysis of experiments with matched groups or repeated measures designs. Psychol Meth. 1996;1:170–7.CrossRef
11.
Hedges L, Olkin I. Statistical methods for meta-analysis. San Diego: Academic Press Inc; 1985.
12.
13.
Avanzini F, Corsetti A, Maglione T, et al. Simple, shared guidelines raise the quality of antihypertensive treatment in routine care. Am Heart J. 2002;144(4):726–32.PubMed
14.
Qureshi NN, Hatcher J, Chaturvedi N, Jafar TH. Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. Br Med J. 2007;335(7628):1030–3.CrossRef
15.
Smith DH, Kramer JM, Perrin N, et al. A randomized trial of direct-to-patient communication to enhance adherence to beta-blocker therapy following myocardial infarction. Arch Intern Med. 2008;168(5):477–83. discussion 483; quiz 447.CrossRefPubMed
16.
Rosen MI, Rigsby MO, Salahi JT, Ryan CE, Cramer JA. Electronic monitoring and counseling to improve medication adherence. Behav Res Ther. 2004;42(4):409–22.CrossRefPubMed
17.
Birtwhistle RV, Godwin MS, Delva MD, et al. Randomised equivalence trial comparing three and six months of follow up of patients with hypertension by family practitioners. Br Med J. 2004;328(7433):204–206B.CrossRef
18.
Hawkins DW, Fiedler FP, Douglas HL, Eschbach RC. Evaluation of a clinical pharmacist in caring for hypertensive and diabetic patients. Am J Hosp Pharm. 1979;36(10):1321–5.PubMed
19.
Kelly JM. Sublingual nitroglycerin: improving patient compliance with a demonstration dose. J Am Board Fam Pract. 1988;1(4):251–4.PubMed
20.
Hunt JS, Siemienczuk J, Pape G, et al. A Randomized controlled trial of team-based care: impact of physician-pharmacist collaboration on uncontrolled hypertension. J Gen Intern Med. 2008.
21.
Gonzalez-Fernandez RA, Rivera M, Torres D, Quiles J, Jackson A. Usefulness of a systemic hypertension in-hospital educational-program. Am J Cardiol. 1990;65(20):1384–6.CrossRefPubMed
22.
Logan AG, Milne BJ, Flanagan PT, Haynes RB. Clinical effectiveness and cost-effectiveness of monitoring blood-pressure of hypertensive employees at work. Hypertension. 1983;5(6):828–36.PubMed
23.
Weymiller AJ, Montori VM, Jones LA, et al. Helping patients with type 2 diabetes mellitus make treatment decisions—Statin choice randomized trial. Arch Intern Med. 2007;167(10):1076–82.CrossRefPubMed
24.
Antonicelli R, Testarmata P, Spazzafumo L, et al. Impact of telemonitoring at home on the management of elderly patients with congestive heart failure. J Telemed Telecare. 2008;14(6):300–5.CrossRefPubMed
25.
Yilmaz MB, Pinar M, Naharci I, et al. Being well-informed about statin is associated with continuous adherence and reaching targets. Cardiovasc Drugs Ther. 2005;19(6):437–40.CrossRefPubMed
26.
Blenkinsopp A, Phelan M, Bourne J, Dakhil N. Extended adherence support by community pharmacists for patients with hypertension: a randomised controlled trial. Int J Pharm Pract. 2000;8(3):165–75.
27.
Bouvy ML, Heerdink ER, Urquhart J, Grobbee DE, Hoe AW, Leufkens HGM. Effect of a pharmacist-led intervention on diuretic compliance in heart failure patients: a randomized controlled study. J Card Fail. 2003;9(5):404–11.CrossRefPubMed
28.
Grant RW, Devita NG, Singer DE, Meigs JB. Improving adherence and reducing medication discrepancies in patients with diabetes. Ann Pharmacother. 2003;37(7–8):962–9.CrossRefPubMed
29.
Jaffray M, Bond C, Watson M, et al. The MEDMAN study: a randomized controlled trial of community pharmacy-led medicines management for patients with coronary heart disease. Fam Pract. 2007;24(2):189–200.CrossRef
30.
Mehos BM, Saseen JJ, MacLaughlin EJ. Effect of pharmacist intervention and initiation of home blood pressure monitoring in patients with uncontrolled hypertension. Pharmacotherapy. 2000;20(11):1384–9.CrossRefPubMed
31.
Murray MD, Young J, Hoke S, et al. Pharmacist intervention to improve medication adherence in heart failure—a randomized trial. Ann Intern Med. 2007;146(10):714–25.PubMed
32.
Odegard PS, Goo A, Hummel J, Williams KL, Gray SL. Caring for poorly controlled diabetes mellitus: a randomized pharmacist intervention. Ann Pharmacother. 2005;39(3):433–40.CrossRefPubMed
33.
Sadik A, Yousif M, McElnay JC. Pharmaceutical care of patients with heart failure. Br J Clin Pharmacol. 2005;60(2):183–93.CrossRefPubMed
34.
Solomon DK, Portner TS, Bass GE, et al. Clinical and economic outcomes in the hypertension and COPD arms of a multicenter outcomes study. J Am Pharm Assoc (Wash). 1998;38(5):574–85.
35.
Sookaneknun P, Richards RM, Sanguansermsri J, Teerasut C. Pharmacist involvement in primary care improves hypertensive patient clinical outcomes. Ann Pharmacother. 2004;38(12):2023–8.CrossRefPubMed
36.
Taylor CT, Byrd DC, Krueger K. Improving primary care in rural Alabama with a pharmacy initiative. Am J Health-Syst Pharm. 2003;60(11):1123–9.PubMed
37.
Varma S, McElnay JC, Hughes CM, Passmore AP, Varma M. Pharmaceutical care of patients with congestive heart failure: Interventions and outcomes. Pharmacotherapy. 1999;19(7):860–9.CrossRefPubMed
38.
Park JJ, Kelly P, Carter BL, Burgess PP. Comprehensive pharmaceutical care in the chain setting. J Am Pharm Assoc (Wash). 1996;NS36(7):443–51.
39.
Edworthy SM, Baptie B, Galvin D, et al. Effects of an enhanced secondary prevention program for patients with heart disease: a prospective randomized trial. Can J Cardiol. 2007;23(13):1066–72.PubMed
40.
Logan AG, Milne BJ, Achber C, Campbell WP, Haynes RB. Work-site treatment of hypertension by specially trained nurses—controlled trial. Lancet. 1979;2(8153):1175–8.CrossRefPubMed
41.
Rudd P, Miller NH, Kaufman J, et al. Nurse management for hypertension—a systems approach. Am J Hypertens. 2004;17(10):921–7.PubMed
42.
Piette JD, Weinberger M, McPhee SJ, Mah CA, Kraemer FB, Crapo LM. Do automated calls with nurse follow-up improve self-care and glycemic control among vulnerable patients with diabetes? Am J Med. 2000;108(1):20–7.CrossRefPubMed
43.
Zarnke KB, Feagan BG, Mahon JL, Feldman RD. A randomized study comparing a patient directed hypertension management strategy with usual office-based care. Am J Hypertens. 1997;10(1):58–67.CrossRefPubMed
44.
Friedman RH, Kazis LE, Jette A, et al. A telecommunications system for monitoring and counseling patients with hypertension—impact on medication adherence and blood pressure control. Am J Hypertens. 1996;9(4):285–92.CrossRefPubMed
45.
Johnson AL, Taylor DW, Sackett DL, Dunnett CW, Shimizu AG. Self-recording of blood pressure in the management of hypertension. Can Med Assoc J. 1978;119(9):1034–9.PubMed
46.
Barrios V, Escobar C, Navarro A, Calderon A, Ruilope LM. Antihypertensive effectiveness of lercanidipine administered using an electronic pillbox compared with usual care in a cohort of mild-to-moderately hypertensive patients: The ELECTRA study. Therapy. 2007;4(4):433–40.CrossRef
47.
Becker LA, Glanz K, Sobel E, Mossey J, Zinn SL, Knott KA. A randomized trial of special packaging of antihypertensive medications. J Fam Pract. 1986;22(4):357–61.PubMed
48.
Fulmer TT, Feldman PH, Kim TS, et al. An intervention study to enhance medication compliance in community-dwelling elderly individuals. J Gerontol Nurs. 1999;25(8):6–14.PubMed
49.
Guthrie RM. The effects of postal and telephone reminders on compliance with pravastatin therapy in a national registry: results of the first myocardial infarction risk reduction program. Clin Ther. 2001;23(6):970–80.CrossRefPubMed
50.
Hagstrom B, Mattsson B, Rost IM, Gunnarsson RK. What happened to the prescriptions? a single, short, standardized telephone call may increase compliance. Fam Pract. 2004;21(1):46–50.CrossRefPubMed
51.
Johnson SS, Driskell MM, Johnson JL, et al. Transtheoretical model intervention for adherence to lipid-lowering drugs. Dis Manag. 2006;9(2):102–14.CrossRefPubMed
52.
Marquez-Contreras E, Martell-Claros N, Gil-Guillen V, et al. Efficacy of a home blood pressure monitoring programme on therapeutic compliance in hypertension: the EAPACUM-HTA study. J Hypertens. 2006;24(1):169–75.CrossRefPubMed
53.
McKenney JM, Munroe WP, Wright JT. Impact of an electronic medication compliance aid on long-term blood-pressure control. J Clin Pharmacol. 1992;32(3):277–83.PubMed
54.
Saunders LD, Irwig LM, Gear JSS, Ramushu DL. A randomized controlled trial of compliance improving strategies in Soweto hypertensives. Med Care. 1991;29(7):669–78.CrossRefPubMed
55.
Schneider PJ, Murphy JE, Pederson CA. Impact of medication packaging on adherence and treatment outcomes in older ambulatory patients. J Am Pharm Assoc. 2008;48(1):58–63.CrossRef
56.
Simkins CV, Wenzloff NJ. Evaluation of a computerized reminder system in the enhancement of patient medication refill compliance. Drug Intell Clin Pharm. 1986;20(10):799–802.PubMed
57.
Skaer TL, Sclar DA, Markowski DJ, Won JK. Effect of value-added utilities on prescription refill compliance and health care expenditures for hypertension. J Hum Hypertens. 1993;7(5):515–8.PubMed
58.
Skaer TL, Sclar DA, Markowski DJ, Won JKH. Effect of value-added utilities on prescription refill compliance and Medicaid health-care expenditures—a study of patients with non-insulin-dependent diabetes-mellitus. J Clin Pharm Ther. 1993;18(4):295–9.CrossRefPubMed
59.
Stewart A, Noakes T, Eales C, Shepard K, Becker P, Veriawa Y. Adherence to cardiovascular risk factor modification in patients with hypertension. Cardiovasc J South Afr. 2005;16(2):102–7.
60.
Marquez Contreras E, Vegazo Garcia O, Claros NM, et al. Efficacy of telephone and mail intervention in patient compliance with antihypertensive drugs in hypertension. ETECUM-HTA study. Blood Press. 2005;14(3):151–8.CrossRefPubMed
61.
Santschi V, Wuerzner G, Schneider MP, Bugnon O, Burnier M. Clinical evaluation of IDAS II, a new electronic device enabling drug adherence monitoring. Eur J Clin Pharmacol. 2007;63(12):1179–84.CrossRefPubMed
62.
Ogedegbe G, Chaplin W, Schoenthaler A, et al. A practice-based trial of motivational interviewing and adherence in hypertensive African Americans. Am J Hypertens. 2008;21(10):1137–43.CrossRefPubMed
63.
Eshelman FN, Fitzloff J. Effect of packaging on patient compliance with an antihypertensive medication. Curr Ther Res Clin Exp. 1976;20(2):215–9.PubMed
64.
Emmett CL, Montgomery AA, Peters TJ, Fahey T. Three-year follow-up of a factorial randomised controlled trial of two decision aids for newly diagnosed hypertensive patients. Br J Gen Pract. 2005;55(516):551–3.PubMed
65.
Takala J. Screening, treatment and adherence to treatment for hypertension. Scand J Prim Health Care. 1983;1(3–4):114–9.CrossRefPubMed
66.
Morisky DE, DeMuth NM, Field-Fass M, Green LW, Levine DM. Evaluation of family health education to build social support for long-term control of high blood pressure. Health Educ Q. 1985;12(1):35–50.PubMed
67.
Powell KM, Edgren B. Failure of educational videotapes to improve medication compliance in a health maintenance organization. Am J Health Syst Pharm. 1995;52(20):2196–9.PubMed
68.
Polack J, Jorgenson D, Robertson P. Evaluation of different methods of providing medication-related education to patients following myocardial infarction. Canadian Pharmacists Journal. 2008;141(4):241–7.CrossRef
69.
Bosworth HB, Olsen MK, Neary A, et al. Take Control of Your Blood pressure (TCYB) study: a multifactorial tailored behavioral and educational intervention for achieving blood pressure control. Patient Educ Couns. 2008;70(3):338–47.CrossRefPubMed
70.
Elliott RA, Barber N, Clifford S, Horne R, Hartley E. The cost effectiveness of a telephone-based pharmacy advisory service to improve adherence to newly prescribed medicines. Pharm World Sci. 2008;30(1):17–23.CrossRefPubMed
71.
Faulkner MA, Wadibia EC, Lucas BD, Hilleman DE. Impact of pharmacy counseling on compliance and effectiveness of combination lipid-lowering therapy in patients undergoing coronary artery revascularization: a randomized, controlled trial. Pharmacotherapy. 2000;20(4):410–6.CrossRefPubMed
72.
Goodyer LI, Miskelly F, Milligan P. Does encouraging good compliance improve patients clinical condition in heart-failure. Br J Clin Pract. 1995;49(4):173–6.PubMed
73.
Hamet P, Campbell N, Curnew G, Eastwood C, Pradhan A. Avapromise: a randomized clinical trial for increasing adherence through behavioural modification in essential hypertension. Exp Clin Cardiol. 2003;7(4):165–72.
74.
Haynes RB, Sackett DL, Gibson ES, et al. Improvement of medication compliance in uncontrolled hypertension. Lancet. 1976;1(7972):1265–8.CrossRefPubMed
75.
Kirscht JP, Kirscht JL, Rosenstock IM. A test of interventions to increase adherence to hypertensive medical regimens. Health Educ Q. 1981;8(3):261–72.PubMed
76.
Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol—a randomized controlled trial. JAMA- J Am Med Assoc. 2006;296(21):2563–71.CrossRef
77.
Lee SSC, Cheung PYP, Chow MSS. Benefits of individualized counseling by the pharmacist on the treatment outcomes of hyperlipidemia in Hong Kong. J Clin Pharmacol. 2004;44(6):632–9.CrossRefPubMed
78.
Lopez Cabezas C, Falces Salvador C, Cubi Quadrada D, et al. Randomized clinical trial of a postdischarge pharmaceutical care program vs regular follow-up in patients with heart failure. Farm Hosp. 2006;30(6):328–42.CrossRefPubMed
79.
Mengden T, Vetter H, Tousset E, Uen S. Management of patients with uncontrolled arterial hypertension–the role of electronic compliance monitoring, 24-h ambulatory blood pressure monitoring and Candesartan/HCTZ. BMC Cardiovasc Disord. 2006;6:36.CrossRefPubMed
80.
Nessman DG, Carnahan JE, Nugent CA. Increasing compliance—patient-operated hypertension groups. Arch Intern Med. 1980;140(11):1427–33.CrossRefPubMed
81.
Rich MW, Gray DB, Beckham V, Wittenberg C, Luther P. Effect of a multidisciplinary intervention on medication compliance in elderly patients with congestive heart failure. Am J Med. 1996;101(3):270–6.CrossRefPubMed
82.
Schectman G, Hiatt J, Hartz A. Telephone contacts do not improve adherence to niacin or bile-acid sequestrant therapy. Ann Pharmacother. 1994;28(1):29–35.PubMed
83.
Schroeder K, Fahey T, Hollinghurst S, Peters TJ. Nurse-led adherence support in hypertension: a randomized controlled trial. Fam Pract. 2005;22(2):144–51.CrossRefPubMed
84.
Sclar DA, Chin A, Skaer TL, Okamoto MP, Nakahiro RK, Gill MA. Effect of health-education in promoting prescription refill compliance among patients with hypertension. Clin Ther. 1991;13(4):489–95.PubMed
85.
Spector R, McGrath P, Uretsky N, Newman R, Cohen P. Does intervention by a nurse improve medication compliance. Arch Intern Med. 1978;138(1):36–40.CrossRefPubMed
86.
Tsuyuki RT, Fradette M, Johnson JA, et al. A multicenter disease management program for hospitalized patients with heart failure. J Card Fail. 2004;10(6):473–80.CrossRefPubMed
87.
Vivian EM. Improving blood pressure control in a pharmacist-managed hypertension clinic. Pharmacotherapy. 2002;22(12):1533–40.CrossRefPubMed
88.
Vrijens B, Belmans A, Matthys K, de Klerk E, Lesaffre E. Effect of intervention through a pharmaceutical care program on patient adherence with prescribed once-daily atorvastatin. Pharmacoepidemiol Drug Saf. 2006;15(2):115–21.CrossRefPubMed
89.
Phumipamorn S, Pongwecharak J, Soorapan S, Pattharachayakul S. Effects of the pharmacist's input on glycaemic control and cardiovascular risks in Muslim diabetes. Prim Care Diabetes. 2008;2(1):31–7.CrossRefPubMed
90.
Riesen WF, Noll G, Dariolo R. Impact of enhanced compliance initiatives on the efficacy of rosuvastatin in reducing low density lipoprotein cholesterol levels in patients with primary hypercholesterolaemia. Swiss Med Wkly. 2008;138(29–30):420–6.PubMed
91.
Gabriel M, Gagnon JP, Bryan CK. Improved patients compliance through use of a daily drug reminder chart. Am J Public Health. 1977;67(10):968–9.CrossRefPubMed
92.
93.
Rehder TL, McCoy LK, Blackwell B, Whitehead W, Robinson A. Improving medication compliance by counseling and special prescription container. Am J Hosp Pharm. 1980;37(3):379–85.PubMed
94.
Burrelle T. Evaluation of an interdisciplinary compliance service for elderly hypertensives. J Geriatr Drug Ther. 1986;1(2):23–51.
Metadata
Title
Physician Effectiveness in Interventions to Improve Cardiovascular Medication Adherence: A Systematic Review
Authors
Sarah L. Cutrona, MD, MPH
Niteesh K. Choudhry, MD, PhD
Margaret Stedman, PhD
Amber Servi, BA
Joshua N. Liberman, PhD
Troyen Brennan, MD, JD
Michael A. Fischer, MD, MPH
M. Alan Brookhart, PhD
William H. Shrank, MD, MSHS
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 10/2010
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-010-1387-9

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