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01-09-2009 | Original Article

A Central Pancreatectomy for Benign or Low-Grade Malignant Neoplasms

Authors: Seiko Hirono, Masaji Tani, Manabu Kawai, Shinomi Ina, Ryohei Nishioka, Motoki Miyazawa, Atsushi Shimizu, Kazuhisa Uchiyama, Hiroki Yamaue

Published in: Journal of Gastrointestinal Surgery | Issue 9/2009

Abstract

Inctroduction

A central pancreatectomy is a parenchyma-sparing procedure that is performed to reduce long-term endocrine and exocrine insufficiency.

Method

In this study, we analyzed the perioperative course, the frequency of postoperative onset of diabetes mellitus, and long-term change of body weight in patients undergoing a central pancreatectomy, in comparison to the patients undergoing a distal pancreatectomy for low-grade neoplasms including cystic neoplasms and neuroendocrine tumors.

Results and Discussion

The rate of postoperative complications including grade B/C pancreatic fistula was no different between both groups. Only one patient undergoing a central pancreatectomy (4.7%) developed new onset of mild diabetes, whereas 35% in the distal pancreatectomy group developed new onset or worsening diabetes (p = 0.0129). The body weight in the distal pancreatectomy group was significant lower than that in the central pancreatectomy group at 1 and 2 years after surgery (1 year; P < 0.0001, 2 years; P = 0.0055), and the body weight in the patients undergoing a central pancreatectomy improved to preoperative values within 2 years after surgery.

Conclusion

A central pancreatectomy is a safe procedure for the treatment of low-grade malignant neoplasms in the pancreatic body; the rate of onset of diabetes is minimal, and the body weight improves early in the postoperative course.

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Title: A Central Pancreatectomy for Benign or Low-Grade Malignant Neoplasms
Authors: Seiko Hirono
Masaji Tani
Manabu Kawai
Shinomi Ina
Ryohei Nishioka
Motoki Miyazawa
Atsushi Shimizu
Kazuhisa Uchiyama
Hiroki Yamaue
Publication date: 01-09-2009
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 9/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-009-0934-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A Central Pancreatectomy for Benign or Low-Grade Malignant Neoplasms

Abstract

Inctroduction

Method

Results and Discussion

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Inctroduction

Method

Results and Discussion

Conclusion

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