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La radiologia medica

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01-01-2020 | Computed Tomography | Chest Radiology

Clinical features of pulmonary cryptococcosis in thin-section CT in immunocompetent and non-AIDS immunocompromised patients

Authors: Xin Sui, Yao Huang, Wei Song, Fuling Zheng, Xiao Wang, Xiaoli Xu, Zixing Wang, Jinmei Jiang, Zhengyu Jin

Published in: La radiologia medica | Issue 1/2020

Abstract

Rational and objectives

To compare thin-section computed tomography (CT) features of pulmonary cryptococcosis (PC) in immunocompetent and non-AIDS immunocompromised patients.

Materials and methods

We retrospectively reviewed CT findings of 18 immunocompetent and 24 non-AIDS immunocompromised patients with clinically proven PC. Different patterns of pulmonary abnormalities between the two groups of patients were compared by Fisher’s exact test.

Results

Pulmonary nodules were present in 37 of the 42 patients. Masses were detected in 16 patients and consolidation in 9. There were 12 patients with a solitary nodule or mass. Masses were associated with nodules in 12 patients. Consolidation was associated with nodules/masses in nine patients. The nodules/masses were associated with cavitations in 13 patients. Margination of nodules/masses was well defined in nine patients and ill-defined in 33. The abnormalities were predominantly distributed in the peripheral region of the lung (n = 29, 69.0%). The presence of cavitations in nodules/masses was significantly more frequent in non-AIDS immunocompromised than in immunocompetent patients (P = 0.001).

Conclusions

The most common thin-section CT feature of PC was pulmonary nodules/masses, which were ill-defined and located peripherally. Cavitations within nodules/masses were more commonly found in non-AIDS immunocompromised patients. PC should be considered in the differential diagnosis of pulmonary nodules/masses.

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Title: Clinical features of pulmonary cryptococcosis in thin-section CT in immunocompetent and non-AIDS immunocompromised patients
Authors: Xin Sui
Yao Huang
Wei Song
Fuling Zheng
Xiao Wang
Xiaoli Xu
Zixing Wang
Jinmei Jiang
Zhengyu Jin
Publication date: 01-01-2020
Publisher: Springer Milan
Keywords: Computed Tomography
Computed Tomography
Cryptococcosis
Pulmonary Nodule
Published in: La radiologia medica / Issue 1/2020
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI: https://doi.org/10.1007/s11547-019-01088-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical features of pulmonary cryptococcosis in thin-section CT in immunocompetent and non-AIDS immunocompromised patients

Abstract

Rational and objectives

Materials and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Rational and objectives

Materials and methods

Results

Conclusions

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