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Forensic Toxicology

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09-01-2022 | Letter to the Editor

Determination of cyanide in blood by GC–MS using a new high selectivity derivatization reagent 1,2,3,3-tetramethyl-3H-indolium iodide

Authors: Yasuhiro Morikawa, Keiji Nishiwaki, Shigeo Suzuki, Kazutaka Shiomi, Isao Nakanishi

Published in: Forensic Toxicology | Issue 2/2022

Excerpt

Dear Editor, …

World Health Organization (2017) Guidelines for drinking-water quality, 4th edition, incorporating the 1st addendum, 4th ed. https://www.who.int/publications/i/item/9789241549950

Seto Y (2002) False cyanide detection. Anal Chem 74:134A–141A. https://doi.org/10.1021/ac021967j (open access article)CrossRefPubMed

Kudo K, Ishida T, Hikiji W, Usumoto T, Umehara T, Nagamatsu K, Tsuji A, Ikeda N (2010) Pattern of poisoning in Japan: selection of drugs and poisons for systematic toxicological analysis. Forensic Toxicol 28:25–32. https://doi.org/10.1007/s11419-009-0088-8CrossRef

Fire Smoke Coalition. http://firesmoke.org/. Accessed 4 Aug 2020

McAllister JL, Roby RJ, Levine B, Purser D (2008) Stability of cyanide in cadavers and in postmortem stored tissue specimens: a review. J Anal Toxicol 32:612–620. https://doi.org/10.1093/jat/32.8.612 (open access article)CrossRefPubMed

Dumas P, Gingras G, LeBlanc A (2005) Isotope dilution-mass spectrometry determination of blood cyanide by headspace gas chromatography. J Anal Toxicol 29:71–75. https://doi.org/10.1093/jat/29.1.71 (open access article)CrossRefPubMed

Murphy KE, Schantz MM, Butler TA et al (2006) Determination of cyanide in blood by isotope-dilution gas chromatography-mass spectrometry. Clin Chem 52:458–467. https://doi.org/10.1373/clinchem.2005.061002 (open access article)CrossRefPubMed

Løbger LL, Petersen HW, Andersen JET (2008) Analysis of cyanide in blood by headspace-isotope-dilution-GC-MS. Anal Lett 41:2564–2586. https://doi.org/10.1080/00032710802363248CrossRef

Goud DR, Sinha Roy K, Pardasani D, Purohit AK, Tak VK, Dubey DK (2020) Gas chromatography-mass spectrometric identification of cyanide using a nucleophilic substitution based derivatization with: S-phenyl benzenethiosulfonate. Anal Methods 12:5839–5845. https://doi.org/10.1039/d0ay01643hCrossRefPubMed

10.

Kage S, Nagata T, Kudo K (1996) Determination of cyanide and thiocyanate in blood by gas chromatography and gas chromatography-mass spectrometry. J Chromatogr B 675:27–32. https://doi.org/10.1016/0378-4347(95)00344-4CrossRef

11.

Miki A, Nishikawa M, Tsuchihashi H (2000) Simultaneous GC-MS determination of azide, cyanide and thiocyanate via phase-transfer-catalyzed pentafluorobenzylation. J Heal Sci 46:81–88. https://doi.org/10.1248/jhs.46.81 (open access article)CrossRef

12.

Tsuge K, Seto Y (2002) Simultaneous detection of anionic toxic substances using GC-MS analysis of pentafluorobenzyl derivatives. Japn J Sci Technol Identif 7:19–35. https://doi.org/10.3408/jasti.7.19 (in Japanese with English abstract; open access article)CrossRef

13.

Kage S, Kudo K, Ikeda N (2012) Determination of inorganic toxic anions in biological samples by gas chromatography/mass spectrometry after derivatization. Japn J Forensic Sci Technol 17:63–74. https://doi.org/10.3408/jafst.17.63 (in Japanese with English abstract; open access article)CrossRef

14.

Kudo K, Usumoto Y, Sameshima N, Okumura M, Tsuji A, Ikeda N (2018) Reliable determination of cyanide, thiocyanate and azide in human whole blood by GC–MS, and its application in NAGINATA–GC–MS screening. Forensic Toxicol 36:160–169. https://doi.org/10.1007/s11419-017-0397-2CrossRef

15.

Liu G, Liu J, Hara K, Wang Y, Yu Y, Gao L, Li L (2009) Rapid determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry with two-step derivatization. J Chromatogr B 877:3054–3058. https://doi.org/10.1016/j.jchromb.2009.07.029CrossRef

16.

Kakehashi H, Shima N, Kamata H, Nishioka H, Ishikawa A, Asai R, Nitta A, Wada M, Nakano S, Matsuta S et al (2020) Development of a new method for cyanide determination using dimethoxytriazinyl (DMT) derivatization. Japn J Forensic Sci Technol 25:141–150. https://doi.org/10.3408/jafst.774 (in Japanese with English abstract; open access article)CrossRef

17.

Yamaguchi A, Miyaguchi H (2021) A screening method for cyanide in blood by dimethoxytriazinyl derivatization-GC/MS. J Chromatogr Sci 59:1–6. https://doi.org/10.1093/chromsci/bmaa081CrossRefPubMed

18.

Madmon M, Shifrovich A, Tamar SY, Weissberg A (2021) Simple and fast determination of free cyanide in drinking water by liquid chromatography electrospray ionization tandem mass spectrometry following “in vial” derivatization. Int J Mass Spectrom 463:116553. https://doi.org/10.1016/j.ijms.2021.116553CrossRef

19.

Lacroix C, Saussereau E, Boulanger F, Goullé JP (2011) Online liquid chromatography-tandem mass spectrometry cyanide determination in blood. J Anal Toxicol 35:143–147. https://doi.org/10.1093/anatox/35.3.143 (open access article)CrossRefPubMed

20.

Jackson R, Logue BA (2017) A review of rapid and field-portable analytical techniques for the diagnosis of cyanide exposure. Anal Chim Acta 960:18–39. https://doi.org/10.1016/j.aca.2016.12.039CrossRefPubMed

21.

Morikawa Y, Hirabara M, Nishiwaki K, Suzuki S, Nakanishi I (2021) A novel turn-on fluorescent sensor for cyanide ions based on the charge transfer transition of phenothiazine/indolium compounds. Mater Adv 2:6104–6111. https://doi.org/10.1039/d1ma00608h (open access article)CrossRef

22.

Park JH, Manivannan R, Jayasudha P, Son YA (2020) Spontaneous optical response towards cyanide ion in water by a reactive binding site probe. Spectrochim Acta A Mol Biomol Spectrosc 233:118190. https://doi.org/10.1016/j.saa.2020.118190CrossRefPubMed

23.

Maji S, Chowdhury B, Pal S, Ghosh P (2018) An indolium ion functionalized naphthalimide chemodosimeter for detection of cyanide in aqueous medium. Inorganica Chim Acta 483:321–328. https://doi.org/10.1016/j.ica.2018.08.040CrossRef

24.

Qu Y, Zhu Y, Wu J, Wu J, Gu Z, Wu Y (2020) Molecular rotor based on dipyridylphenylamine: near-infrared enhancement emission from restriction of molecular rotation and applications in viscometer and bioprobe. Dyes Pigm 172: https://doi.org/10.1016/j.dyepig.2019.107795CrossRef

25.

Huang X, Gu X, Zhang G, Zhang D (2012) A highly selective fluorescence turn-on detection of cyanide based on the aggregation of tetraphenylethylene molecules induced by chemical reaction. Chem Commun 48:12195–12197. https://doi.org/10.1039/c2cc37094hCrossRef

26.

Cheng S, Pan X, Shi M, Su T, Zhang C, Zhao W, Dong W (2020) A coumarin-connected carboxylic indolinium sensor for cyanide detection in absolute aqueous medium and its application in biological cell imaging. Spectrochim Acta A Mol Biomol Spectrosc 228:117710. https://doi.org/10.1016/j.saa.2019.117710CrossRefPubMed

27.

Deng K, Wang L, Xia Q, Liu R, Qu J (2019) A turn-on fluorescent chemosensor based on aggregation-induced emission for cyanide detection and its bioimaging applications. Sens Actuators B Chem 296:126645. https://doi.org/10.1016/j.snb.2019.126645CrossRef

28.

Malkondu S, Erdemir S, Karakurt S (2020) Red and blue emitting fluorescent probe for cyanide and hypochlorite ions: biological sensing and environmental analysis. Dyes Pigm 174:108019. https://doi.org/10.1016/j.dyepig.2019.108019CrossRef

29.

Dong ZM, Ren H, Wang JN, Wang Y (2020) A new naphthopyran-based chemodosimeter with aggregation-induced emission: selective dual-channel detection of cyanide ion in aqueous medium and test strips. Microchem J 155:104676. https://doi.org/10.1016/j.microc.2020.104676CrossRef

30.

Bhaskar R, Vijayakumar V, Srinivasadesikan V, Lee S-L, Sarveswari S (2020) Rationally designed imidazole derivative as colorimetric and fluorometric sensor for selective, qualitative and quantitative cyanide ion detection in real time samples. Spectrochim Acta A Mol Biomol Spectrosc 234:118212. https://doi.org/10.1016/j.saa.2020.118212CrossRefPubMed

31.

Lindsay AE, Greenbaum AR, O’Hare D (2004) Analytical techniques for cyanide in blood and published blood cyanide concentrations from healthy subjects and fire victims. Anal Chim Acta 511:185–195. https://doi.org/10.1016/j.aca.2004.02.006CrossRef

32.

Pharmaceutical Society of Japan (2017) The Standard method of chemical analysis in poisoning 2017. Tokyo Kagaku Doujin, Tokyo (in Japanese)

33.

Ragaitė G, Dagilienė M, Krikštolaitytė S, Martynaitis V, Šačkus A (2016) Synthesis of trifluoromethyl group bearing indoline-based heterocyclic systems and their application for the detection of cyanide. J Fluor Chem 182:34–40. https://doi.org/10.1016/j.jfluchem.2015.11.009CrossRef

34.

Tsuge K, Kataoka M, Seto Y (2000) Cyanide and thiocyanate levels in blood and saliva of healthy adult volunteers. J Health Sci 46:343–350. https://doi.org/10.1248/jhs.46.343CrossRef

35.

Food and Drug Administration (2018) Bioanalytical method validation guidance for industry. https://www.fda.gov/files/drugs/published/Bioanalytical-Method-Validation-Guidance-for-Industry.pdf. Accessed 20 Nov 2021

36.

US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry (2006) Toxicology profile for cyanide. https://www.atsdr.cdc.gov/toxprofiles/tp8.pdf. Accessed 20 Nov 2021

37.

Stamyr K, Thelander G, Ernstgård L, Ahlner J, Johanson G (2012) Swedish forensic data 1992–2009 suggest hydrogen cyanide as an important cause of death in fire victims. Inhal Toxicol 24:194–199. https://doi.org/10.3109/08958378.2012.660285CrossRefPubMed

Title: Determination of cyanide in blood by GC–MS using a new high selectivity derivatization reagent 1,2,3,3-tetramethyl-3H-indolium iodide
Authors: Yasuhiro Morikawa
Keiji Nishiwaki
Shigeo Suzuki
Kazutaka Shiomi
Isao Nakanishi
Publication date: 09-01-2022
Publisher: Springer Nature Singapore
Published in: Forensic Toxicology / Issue 2/2022
Print ISSN: 1860-8965
Electronic ISSN: 1860-8973
DOI: https://doi.org/10.1007/s11419-021-00610-w

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Determination of cyanide in blood by GC–MS using a new high selectivity derivatization reagent 1,2,3,3-tetramethyl-3H-indolium iodide

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