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Published in: Sleep and Breathing 2/2014

01-05-2014 | Original Article

Validation of blood pressure monitoring using pulse transit time in heart failure patients with Cheyne–Stokes respiration undergoing adaptive servoventilation therapy

Authors: Jens Spießhöfer, Jessica Heinrich, Thomas Bitter, Christina Efken, Roman Lehmann, Siegfried Eckert, Dieter Horstkotte, Olaf Oldenburg

Published in: Sleep and Breathing | Issue 2/2014

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Abstract

Purpose

Using pulse transit time (PTT) and an ECG appears to be a promising alternative for invasive or noninvasive monitoring of blood pressure (BP). This study assessed the validity of PTT for BP monitoring in clinical practice.

Methods

Twenty-nine patients with chronic heart failure (HF; 27 male, 70.5 ± 9.9 years) and nocturnal Cheyne–Stokes respiration were noninvasively ventilated for one hour using adaptive servoventilation (ASV) therapy (PaceWave™, ResMed). BP was measured using two devices (oscillometrically via Task Force Monitor, CNSystems and PTT via SOMNOscreen™, Somnomedics) at least every 7 min for 30 min before, during, and after ASV.

Results

Mean systolic BP was 118.1 ± 14.4 mmHg vs. 115.9 ± 14.1 mmHg for oscillometric method vs PTT, respectively. Corresponding values for diastolic BP were 72.3 ± 10.3 mmHg and 69.4 ± 11.1 mmHg. While clinically comparable, differences between the two methods were statistically significant (p < 0.05). The difference between the two methods showed an increasing trend over time. A total of 18.5 % of PTT-based measurements could not be analyzed. The direction of a change in BP was opposite for PTT vs oscillometry for 17.0 % and 32.8 % of systolic and diastolic BP measurements, respectively.

Conclusions

When monitoring BP in HF patients, overall BP monitoring using PTT is comparable to oscillometry for a period of 2 h (including a 1-h ASV phase). However, PTT shows a tendency to underestimate BP over time and during ASV.
Literature
1.
go back to reference Bramwell C (1937) The arterial pulse in health and disease. Lancet 230:239–247CrossRef Bramwell C (1937) The arterial pulse in health and disease. Lancet 230:239–247CrossRef
3.
go back to reference Schmitt OH (1955) Mechanism of the excitatory process in biological systems. Office Naval Research progress report. No. 24609 Schmitt OH (1955) Mechanism of the excitatory process in biological systems. Office Naval Research progress report. No. 24609
4.
go back to reference Simmons EM, Leader H, Friedman SA, Davis B, Lee D, Winsor T, Caceres CA (1967) A computer program for the peripheral pulse wave. Am J Cardiol 19:827–831PubMedCrossRef Simmons EM, Leader H, Friedman SA, Davis B, Lee D, Winsor T, Caceres CA (1967) A computer program for the peripheral pulse wave. Am J Cardiol 19:827–831PubMedCrossRef
6.
go back to reference Mackenzie JS (1916) Principles of diagnosis and treatment in heart affections, 2nd edn. Henry Frowde, London, UK Mackenzie JS (1916) Principles of diagnosis and treatment in heart affections, 2nd edn. Henry Frowde, London, UK
7.
go back to reference Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A (2001) Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37:1236–1241PubMedCrossRef Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A (2001) Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37:1236–1241PubMedCrossRef
8.
go back to reference Safar ME, Henry O, Meaume S (2002) Aortic pulse wave velocity: an independent marker of cardiovascular risk. Am J Geriatr Cardiol 11:295–304PubMedCrossRef Safar ME, Henry O, Meaume S (2002) Aortic pulse wave velocity: an independent marker of cardiovascular risk. Am J Geriatr Cardiol 11:295–304PubMedCrossRef
9.
go back to reference Bakker JP, Campbell AJ, Neill AM (2011) Pulse wave analysis in a pilot randomised controlled trial of auto-adjusting and continuous positive airway pressure for obstructive sleep apnoea. Sleep Breath 15:325–332PubMedCrossRef Bakker JP, Campbell AJ, Neill AM (2011) Pulse wave analysis in a pilot randomised controlled trial of auto-adjusting and continuous positive airway pressure for obstructive sleep apnoea. Sleep Breath 15:325–332PubMedCrossRef
10.
go back to reference Buchner NJ, Quack I, Stegbauer J, Woznowski M, Kaufmann A, Rump LC (2012) Treatment of obstructive sleep apnea reduces arterial stiffness. Sleep Breath 16:123–133PubMedCrossRef Buchner NJ, Quack I, Stegbauer J, Woznowski M, Kaufmann A, Rump LC (2012) Treatment of obstructive sleep apnea reduces arterial stiffness. Sleep Breath 16:123–133PubMedCrossRef
11.
go back to reference Hirata K, Kawakami M, O'Rourke MF (2006) Pulse wave analysis and pulse wave velocity—a review of blood pressure interpretation 100 years after Korotkov. Circulation 70:1231–1239CrossRef Hirata K, Kawakami M, O'Rourke MF (2006) Pulse wave analysis and pulse wave velocity—a review of blood pressure interpretation 100 years after Korotkov. Circulation 70:1231–1239CrossRef
12.
go back to reference O'Rourke MF, Seward JB (2006) Central arterial pressure and arterial pressure pulse: new views entering the second century after Korotkov. Mayo Clin Proc 81:1057–1068PubMedCrossRef O'Rourke MF, Seward JB (2006) Central arterial pressure and arterial pressure pulse: new views entering the second century after Korotkov. Mayo Clin Proc 81:1057–1068PubMedCrossRef
13.
go back to reference Oldenburg O, Bartsch S, Bitter T, Schmalgemeier H, Fischbach T, Westerheide N, Horstkotte D (2012) Hypotensive effects of positive airway pressure ventilation in heart failure patients with sleep-disordered breathing. Sleep Breath 16:753–757PubMedCrossRef Oldenburg O, Bartsch S, Bitter T, Schmalgemeier H, Fischbach T, Westerheide N, Horstkotte D (2012) Hypotensive effects of positive airway pressure ventilation in heart failure patients with sleep-disordered breathing. Sleep Breath 16:753–757PubMedCrossRef
14.
go back to reference Yang SQ, Han LL, Dong XL, Wang CY, Xia H, Liu P, Wang JH, He PP, Liu SN, Li MX (2012) Mal-effects of obstructive sleep apnea on the heart. Sleep Breath 16:717–722PubMedCrossRef Yang SQ, Han LL, Dong XL, Wang CY, Xia H, Liu P, Wang JH, He PP, Liu SN, Li MX (2012) Mal-effects of obstructive sleep apnea on the heart. Sleep Breath 16:717–722PubMedCrossRef
15.
go back to reference Won CH, Chun HJ, Chandra SM, Sarinas PS, Chitkara RK, Heidenreich PA (2013) Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury. Sleep Breath 17:85–91PubMedCrossRef Won CH, Chun HJ, Chandra SM, Sarinas PS, Chitkara RK, Heidenreich PA (2013) Severe obstructive sleep apnea increases mortality in patients with ischemic heart disease and myocardial injury. Sleep Breath 17:85–91PubMedCrossRef
16.
go back to reference Shah NA, Yaggi HK, Concato J, Mohsenin V (2010) Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death. Sleep Breath 14:131–136PubMedCrossRef Shah NA, Yaggi HK, Concato J, Mohsenin V (2010) Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death. Sleep Breath 14:131–136PubMedCrossRef
17.
go back to reference Tholl U, Anlauf M, Lichtblau U, Dammer R, Roggenbuck U (2006) The Stamp of Quality of the German Hypertension League for the clinical validation of blood pressure measuring devices: results from 51 devices under test. Dtsch Med Wochenschr 131:31–36CrossRef Tholl U, Anlauf M, Lichtblau U, Dammer R, Roggenbuck U (2006) The Stamp of Quality of the German Hypertension League for the clinical validation of blood pressure measuring devices: results from 51 devices under test. Dtsch Med Wochenschr 131:31–36CrossRef
18.
go back to reference Schmalgemeier H, Bitter T, Bartsch S, Bullert K, Fischbach T, Eckert S, Horstkotte D, Oldenburg O (2011) Pulse transit time: validation of blood pressure measurement under positive airway pressure ventilation. Sleep Breath 16:1105–1112PubMedCrossRef Schmalgemeier H, Bitter T, Bartsch S, Bullert K, Fischbach T, Eckert S, Horstkotte D, Oldenburg O (2011) Pulse transit time: validation of blood pressure measurement under positive airway pressure ventilation. Sleep Breath 16:1105–1112PubMedCrossRef
19.
go back to reference Bartsch S, Ostojic D, Schmalgemeier H, Bitter T, Westerheide N, Eckert S, Horstkotte D, Oldenburg O (2010) Validation of continuous blood pressure measurements by pulse transit time: a comparison with invasive measurements in a cardiac intensive care unit. Dtsch Med Wochenschr 135:2406–2412PubMedCrossRef Bartsch S, Ostojic D, Schmalgemeier H, Bitter T, Westerheide N, Eckert S, Horstkotte D, Oldenburg O (2010) Validation of continuous blood pressure measurements by pulse transit time: a comparison with invasive measurements in a cardiac intensive care unit. Dtsch Med Wochenschr 135:2406–2412PubMedCrossRef
20.
go back to reference Fortin J, Habenbacher W, Heller A, Hacker A, Grüllenberger R, Innerhofer J, Passath H, Wagner C, Haitchi G, Flotzinger D, Pacher R, Wach P (2006) Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurement. Comput Biol Med 36:1185–1203PubMedCrossRef Fortin J, Habenbacher W, Heller A, Hacker A, Grüllenberger R, Innerhofer J, Passath H, Wagner C, Haitchi G, Flotzinger D, Pacher R, Wach P (2006) Non-invasive beat-to-beat cardiac output monitoring by an improved method of transthoracic bioimpedance measurement. Comput Biol Med 36:1185–1203PubMedCrossRef
21.
go back to reference Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMedCrossRef Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMedCrossRef
22.
go back to reference Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 8:597–619PubMedCentralPubMed Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 8:597–619PubMedCentralPubMed
23.
go back to reference Davies RJO, Jenkins NE, Stradling JR (1994) Effect of measuring ambulatory blood pressure on sleep and on blood pressure during sleep. Br Med J 308:820–823CrossRef Davies RJO, Jenkins NE, Stradling JR (1994) Effect of measuring ambulatory blood pressure on sleep and on blood pressure during sleep. Br Med J 308:820–823CrossRef
24.
go back to reference Naschitz JE, Bezobchuk S, Mussafia-Priselac R, Sundick S, Dreyfuss D, Khorshidi I, Karidis A, Manor H, Nagar M, Peck ER, Peck S, Storch S, Rosner I, Gaitini L (2004) Pulse transit time by R-wave-gated infrared photoplethysmography: review of the literature and personal experience. J Clin Monit 18:333–342CrossRef Naschitz JE, Bezobchuk S, Mussafia-Priselac R, Sundick S, Dreyfuss D, Khorshidi I, Karidis A, Manor H, Nagar M, Peck ER, Peck S, Storch S, Rosner I, Gaitini L (2004) Pulse transit time by R-wave-gated infrared photoplethysmography: review of the literature and personal experience. J Clin Monit 18:333–342CrossRef
25.
go back to reference MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, Abbott R, Godwin J, Dyer A, Stamler J (1990) Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 335:765–774PubMedCrossRef MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, Abbott R, Godwin J, Dyer A, Stamler J (1990) Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 335:765–774PubMedCrossRef
26.
go back to reference O’Brien E, Pickering T, Asmar R, Myers M, Parati G, Staessen J, Mengden T, Imai Y, Waeber B, Palatini P, Gerin W (2002) Working Group on Blood Pressure Monitoring of the European Society of Hypertension: international protocol for validation of blood pressure measuring devices in adults. Blood Press Monit 7:3–17PubMedCrossRef O’Brien E, Pickering T, Asmar R, Myers M, Parati G, Staessen J, Mengden T, Imai Y, Waeber B, Palatini P, Gerin W (2002) Working Group on Blood Pressure Monitoring of the European Society of Hypertension: international protocol for validation of blood pressure measuring devices in adults. Blood Press Monit 7:3–17PubMedCrossRef
27.
go back to reference Woolam GL, Schnur PL, Vallbona C, Hoff HE (1962) The pulse wave velocity as an early indicator of atherosclerosis in diabetic subjects. Circulation 25:533–539PubMedCrossRef Woolam GL, Schnur PL, Vallbona C, Hoff HE (1962) The pulse wave velocity as an early indicator of atherosclerosis in diabetic subjects. Circulation 25:533–539PubMedCrossRef
28.
go back to reference Wagner DR, Roesch N, Harpes P, Körtke H, Plumer P, Saberin A, Chakoutio V, Oundjede D, Delagardelle C, Beissel J, Gilson G, Kindermann I, Böhm M (2010) Relationship between pulse transit time and blood pressure is impaired in patients with chronic heart failure. Clin Res Cardiol 99:657–664PubMedCrossRef Wagner DR, Roesch N, Harpes P, Körtke H, Plumer P, Saberin A, Chakoutio V, Oundjede D, Delagardelle C, Beissel J, Gilson G, Kindermann I, Böhm M (2010) Relationship between pulse transit time and blood pressure is impaired in patients with chronic heart failure. Clin Res Cardiol 99:657–664PubMedCrossRef
29.
go back to reference Yin M, Nakayama M, Miyazaki S, Ishikawa K (2008) How much influence does inspiration have on pulse transit time in sleep apnea? Otolaryngol Head Neck Surg 138:619–625PubMedCrossRef Yin M, Nakayama M, Miyazaki S, Ishikawa K (2008) How much influence does inspiration have on pulse transit time in sleep apnea? Otolaryngol Head Neck Surg 138:619–625PubMedCrossRef
30.
go back to reference Young CC, Mark JB, White W, DeBree A, Vender JS, Fleming A (1995) Clinical evaluation of continuous noninvasive blood pressure monitoring: accuracy and tracking capabilities. J Clin Monit 11:245–252PubMedCrossRef Young CC, Mark JB, White W, DeBree A, Vender JS, Fleming A (1995) Clinical evaluation of continuous noninvasive blood pressure monitoring: accuracy and tracking capabilities. J Clin Monit 11:245–252PubMedCrossRef
31.
go back to reference Foo JY, Lim CS, Wang P (2006) Evaluation of blood pressure changes using vascular transit time. Physiol Meas 27:685–694PubMedCrossRef Foo JY, Lim CS, Wang P (2006) Evaluation of blood pressure changes using vascular transit time. Physiol Meas 27:685–694PubMedCrossRef
32.
go back to reference Wong MY, Pickwell-MacPherson E, Zhang YT (2009) The acute effects of running on blood pressure estimation using pulse transit time in normotensive subjects. Eur J Appl Physiol 107:169–175PubMedCrossRef Wong MY, Pickwell-MacPherson E, Zhang YT (2009) The acute effects of running on blood pressure estimation using pulse transit time in normotensive subjects. Eur J Appl Physiol 107:169–175PubMedCrossRef
33.
go back to reference Chen W, Kobayashi T, Ichikawa S, Takeuchi Y, Togawa T (2000) Continuous estimation of systolic blood pressure using the pulse arrival time and intermittent calibration. Med Biol Eng Comput 38:569–574PubMedCrossRef Chen W, Kobayashi T, Ichikawa S, Takeuchi Y, Togawa T (2000) Continuous estimation of systolic blood pressure using the pulse arrival time and intermittent calibration. Med Biol Eng Comput 38:569–574PubMedCrossRef
34.
go back to reference Eckert S, Horstkotte D (2002) Comparison of Portapres non-invasive blood pressure measurement in the finger with intra-aortic pressure measurement during incremental bicycle exercise. Blood Press Monit 7:179–183PubMedCrossRef Eckert S, Horstkotte D (2002) Comparison of Portapres non-invasive blood pressure measurement in the finger with intra-aortic pressure measurement during incremental bicycle exercise. Blood Press Monit 7:179–183PubMedCrossRef
35.
go back to reference Bruner JM, Krenis LJ, Kunsman JM, Sherman AP (1981) Comparison of direct and indirect methods of measuring arterial blood pressure. Med Instrum 15:11–21PubMed Bruner JM, Krenis LJ, Kunsman JM, Sherman AP (1981) Comparison of direct and indirect methods of measuring arterial blood pressure. Med Instrum 15:11–21PubMed
Metadata
Title
Validation of blood pressure monitoring using pulse transit time in heart failure patients with Cheyne–Stokes respiration undergoing adaptive servoventilation therapy
Authors
Jens Spießhöfer
Jessica Heinrich
Thomas Bitter
Christina Efken
Roman Lehmann
Siegfried Eckert
Dieter Horstkotte
Olaf Oldenburg
Publication date
01-05-2014
Publisher
Springer Berlin Heidelberg
Published in
Sleep and Breathing / Issue 2/2014
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-013-0895-3

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