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25-03-2022 | COVID-19 Vaccination | Original Paper

A SARS-CoV-2 Outbreak Among Nursing Home Residents Vaccinated with a Booster Dose of mRNA COVID-19 Vaccine

Authors: Giancarlo Ripabelli, Michela Lucia Sammarco, Giovanni Rezza, Antonio D’Amico, Roberta De Dona, Mariagrazia Iafigliola, Albino Parente, Nicandro Samprati, Arturo Santagata, Carmen Adesso, Anna Natale, Michela Anna Di Palma, Fabio Cannizzaro, Cosimo Dentizzi, Paola Stefanelli, Manuela Tamburro

Published in: Journal of Community Health | Issue 4/2022

Abstract

This study describes a SARS-CoV-2 outbreak caused by the Delta (B.1.617.2) variant in a nursing home in Central Italy during October–November 2021. Trained interviewers collected data from residents, staff, and administration officers with an agreed informed consent procedure. Thirty-two (44.5%) out of 72 residents (median age 89 years) and six (26.1%) of 23 healthcare workers were found to be infected with SARS-CoV-2. Infections occurred more often among residents with a higher index of independence in daily living activities, suggesting an increased risk for those with more interactions. Twenty-five infected residents (78.1%) received the booster dose of mRNA anti-COVID-19 vaccine > 7 days before SARS-CoV-2 onset. Half of the infected residents had mild symptoms, and only three required hospitalisation, one of whom died from COVID-19 complications. The study underlines the effectiveness of a booster dose in providing a high protection against severe disease and hospitalisation even among vulnerable individuals infected with the Delta variant of concern.

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Title: A SARS-CoV-2 Outbreak Among Nursing Home Residents Vaccinated with a Booster Dose of mRNA COVID-19 Vaccine
Authors: Giancarlo Ripabelli
Michela Lucia Sammarco
Giovanni Rezza
Antonio D’Amico
Roberta De Dona
Mariagrazia Iafigliola
Albino Parente
Nicandro Samprati
Arturo Santagata
Carmen Adesso
Anna Natale
Michela Anna Di Palma
Fabio Cannizzaro
Cosimo Dentizzi
Paola Stefanelli
Manuela Tamburro
Publication date: 25-03-2022
Publisher: Springer US
Keywords: COVID-19 Vaccination
Vaccination
SARS-CoV-2
Care
COVID-19
Published in: Journal of Community Health / Issue 4/2022
Print ISSN: 0094-5145
Electronic ISSN: 1573-3610
DOI: https://doi.org/10.1007/s10900-022-01082-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A SARS-CoV-2 Outbreak Among Nursing Home Residents Vaccinated with a Booster Dose of mRNA COVID-19 Vaccine

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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