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Published in: Journal of Interventional Cardiac Electrophysiology 1/2013

01-06-2013

Predictive value of total atrial conduction time measured with tissue Doppler imaging for postoperative atrial fibrillation after coronary artery bypass surgery

Authors: Mehmet Fatih Özlü, Kemalettin Erdem, Gülhanım Kırış, Ali İhsan Parlar, Abdullah Demirhan, Selim Suzi Ayhan, Alim Erdem, Serkan Öztürk, Ümit Yaşar Tekelioğlu, Mehmet Yazıcı

Published in: Journal of Interventional Cardiac Electrophysiology | Issue 1/2013

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Abstract

Objective

Postoperative atrial fibrillation (POAF) complicating coronary artery bypass grafting surgery (CABG) increases morbidity and stroke risk. Total atrial conduction time (PA-TDI duration) has been identified as an independent predictor of new-onset atrial fibrillation (AF). We aimed to assess whether PA-TDI duration is a predictor of AF after CABG.

Methods

In 128 patients who had undergone CABG, preoperative clinical and echocardiographic data were compared between patients with and without POAF. The PA-TDI duration was assessed by measuring the time interval between the beginning of the P wave on the surface ECG and point of the peak A wave on TDI from left atrium (LA) lateral wall just over the mitral annulus.

Results

Patients with POAF (38/128, 29.6 %) were older (68.1 ± 11.1 vs. 59.3 ± 10.2 years; p < 0.001), had higher LA maximum volume, had prolonged PA-TDI duration, and had lower ejection fraction compared with patients without POAF. PA-TDI duration was found to be significantly increased in POAF group (134.3 ± 19.7 vs. 112.5 ± 17.7 ms; p = 0.01). On multivariate analysis, age (95 % CI = 1.03–1.09; p = 0.003), LA maximum volume (95 % CI = 1.01–1.06; p = 0.03), and prolonged PA-TDI duration (95 % CI, 1.02–1.05; p = 0.001) were found to be the independent risk factors of POAF.

Conclusions

In this study, LA maximum volume and PA-TDI duration were found to be the independent predictors of the development of POAF after CABG. Echocardiographic predictors of left atrial electromechanical dysfunction may be useful in risk stratifying of patients in terms of POAF development after CABG.
Literature
1.
go back to reference Amar, D., Shi, W., Hogue, C. W., Jr., et al. (2004). Clinical prediction rule for atrial fibrillation after coronary artery bypass grafting. Journal of the American College of Cardiology, 44, 1248–1253.PubMedCrossRef Amar, D., Shi, W., Hogue, C. W., Jr., et al. (2004). Clinical prediction rule for atrial fibrillation after coronary artery bypass grafting. Journal of the American College of Cardiology, 44, 1248–1253.PubMedCrossRef
2.
go back to reference Hogue, C. W., & Hyder, M. L. (2000). Atrial fibrillation after cardiac operation: risks, mechanisms, and treatment. The Annals of Thoracic Surgery, 69, 300–306.PubMedCrossRef Hogue, C. W., & Hyder, M. L. (2000). Atrial fibrillation after cardiac operation: risks, mechanisms, and treatment. The Annals of Thoracic Surgery, 69, 300–306.PubMedCrossRef
3.
go back to reference Mathew, J. P., Fontes, M. L., Tudor, I. C., et al. (2004). A multicenter risk index for atrial fibrillation after cardiac surgery. Journal of the American Medical Association, 291, 1720–1729.PubMedCrossRef Mathew, J. P., Fontes, M. L., Tudor, I. C., et al. (2004). A multicenter risk index for atrial fibrillation after cardiac surgery. Journal of the American Medical Association, 291, 1720–1729.PubMedCrossRef
4.
go back to reference Villareal, R. P., Hariharan, R., Liu, B. C., et al. (2004). Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. Journal of the American College of Cardiology, 43, 742–748.PubMedCrossRef Villareal, R. P., Hariharan, R., Liu, B. C., et al. (2004). Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. Journal of the American College of Cardiology, 43, 742–748.PubMedCrossRef
5.
go back to reference Mahoney, E. M., Thompson, T. D., Veledar, E., Williams, J., & Weintraub, W. S. (2002). Cost-effectiveness of targeting patients undergoing cardiac surgery for therapy with intravenous amiodarone to prevent atrial fibrillation. Journal of the American College of Cardiology, 40, 737–742.PubMedCrossRef Mahoney, E. M., Thompson, T. D., Veledar, E., Williams, J., & Weintraub, W. S. (2002). Cost-effectiveness of targeting patients undergoing cardiac surgery for therapy with intravenous amiodarone to prevent atrial fibrillation. Journal of the American College of Cardiology, 40, 737–742.PubMedCrossRef
6.
go back to reference Sezai, A., Hata, M., Niino, T., et al. (2009). Study of the factors related to atrial fibrillation after coronary artery bypass grafting: a search for a marker to predict the occurrence of atrial fibrillation before surgical intervention. The Journal of Thoracic and Cardiovascular Surgery, 137, 895–900.PubMedCrossRef Sezai, A., Hata, M., Niino, T., et al. (2009). Study of the factors related to atrial fibrillation after coronary artery bypass grafting: a search for a marker to predict the occurrence of atrial fibrillation before surgical intervention. The Journal of Thoracic and Cardiovascular Surgery, 137, 895–900.PubMedCrossRef
7.
go back to reference El-Chami, M. F., Kilgo, P., Thourani, V., et al. (2010). New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology, 55, 1370–1376.PubMedCrossRef El-Chami, M. F., Kilgo, P., Thourani, V., et al. (2010). New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology, 55, 1370–1376.PubMedCrossRef
8.
go back to reference Shen, J., Lall, S., Zheng, V., Buckley, P., Damiano, R. J., & Schuessler, R. B. (2011). The persistent problem of new-onset postoperative atrial fibrillation: a single institution experience over two decades. The Journal of Thoracic and Cardiovascular Surgery, 141, 559–570.PubMedCrossRef Shen, J., Lall, S., Zheng, V., Buckley, P., Damiano, R. J., & Schuessler, R. B. (2011). The persistent problem of new-onset postoperative atrial fibrillation: a single institution experience over two decades. The Journal of Thoracic and Cardiovascular Surgery, 141, 559–570.PubMedCrossRef
9.
go back to reference Den Uijl, D. W., Gawrysiak, M., Tops, L. F., Trines, S. A., Zeppenfeld, K., Schalij, M. J., et al. (2011). Prognostic value of total atrial conduction time estimated with tissue Doppler imaging to predict the recurrence of atrial fibrillation after radiofrequency catheter ablation. Europace, 13, 1533–1540.PubMedCrossRef Den Uijl, D. W., Gawrysiak, M., Tops, L. F., Trines, S. A., Zeppenfeld, K., Schalij, M. J., et al. (2011). Prognostic value of total atrial conduction time estimated with tissue Doppler imaging to predict the recurrence of atrial fibrillation after radiofrequency catheter ablation. Europace, 13, 1533–1540.PubMedCrossRef
10.
go back to reference Merckx, K. L., De Vos, C. B., Palmans, A., Habets, J., Cheriex, E. C., Crijns, H. J., et al. (2005). Atrial activation time determined by transthoracic Doppler tissue imaging can be used as an estimate of the total duration of atrial electrical activation. Journal of the American Society of Echocardiography, 18(9), 940–944.PubMedCrossRef Merckx, K. L., De Vos, C. B., Palmans, A., Habets, J., Cheriex, E. C., Crijns, H. J., et al. (2005). Atrial activation time determined by transthoracic Doppler tissue imaging can be used as an estimate of the total duration of atrial electrical activation. Journal of the American Society of Echocardiography, 18(9), 940–944.PubMedCrossRef
11.
go back to reference Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., et al. (2005). Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. Journal of the American Society of Echocardiography, 18, 1440–1463.PubMedCrossRef Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., et al. (2005). Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. Journal of the American Society of Echocardiography, 18, 1440–1463.PubMedCrossRef
12.
go back to reference Quinones, M. A., Otto, C. M., Stoddard, M., Waggoner, A., & Zoghbi, W. A. (2002). Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. Journal of the American Society of Echocardiography, 15, 167–184.PubMedCrossRef Quinones, M. A., Otto, C. M., Stoddard, M., Waggoner, A., & Zoghbi, W. A. (2002). Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. Journal of the American Society of Echocardiography, 15, 167–184.PubMedCrossRef
13.
go back to reference Acar, G., Akcay, A., Sökmen, A., Özkaya, M., Güler, E., Sökmen, G., et al. (2009). Assessment of atrial electromechanical delay, diastolic functions, and left atrial mechanical functions in patients with type 1 diabetes mellitus. Journal of the American Society of Echocardiography, 22, 732–738.PubMedCrossRef Acar, G., Akcay, A., Sökmen, A., Özkaya, M., Güler, E., Sökmen, G., et al. (2009). Assessment of atrial electromechanical delay, diastolic functions, and left atrial mechanical functions in patients with type 1 diabetes mellitus. Journal of the American Society of Echocardiography, 22, 732–738.PubMedCrossRef
14.
go back to reference Antoni, M. L., Bertini, M., Atary, J. Z., Delgado, V., ten Brinke, E. A., Boersma, E., et al. (2010). Predictive value of total atrial conduction time estimated with tissue Doppler imaging for the development of new-onset atrial fibrillation after acute myocardial infarction. The American Journal of Cardiology, 106(2), 198–203.PubMedCrossRef Antoni, M. L., Bertini, M., Atary, J. Z., Delgado, V., ten Brinke, E. A., Boersma, E., et al. (2010). Predictive value of total atrial conduction time estimated with tissue Doppler imaging for the development of new-onset atrial fibrillation after acute myocardial infarction. The American Journal of Cardiology, 106(2), 198–203.PubMedCrossRef
15.
go back to reference Steinberg, J. S. (2004). Postoperative atrial fibrillation: a billion-dollar problem. Journal of the American College of Cardiology, 43, 1001–1003.PubMedCrossRef Steinberg, J. S. (2004). Postoperative atrial fibrillation: a billion-dollar problem. Journal of the American College of Cardiology, 43, 1001–1003.PubMedCrossRef
16.
go back to reference Blommaert, D., Gonzalez, M., Mucumbitsi, J., et al. (2000). Effective prevention of atrial fibrillation by continuous atrial overdrive pacing after coronary artery bypass surgery. Journal of the American College of Cardiology, 35, 1411–1415.PubMedCrossRef Blommaert, D., Gonzalez, M., Mucumbitsi, J., et al. (2000). Effective prevention of atrial fibrillation by continuous atrial overdrive pacing after coronary artery bypass surgery. Journal of the American College of Cardiology, 35, 1411–1415.PubMedCrossRef
17.
go back to reference Budeus, M., Hennersdorf, M., Perings, S., et al. (2006). Amiodarone prophylaxis for atrial fibrillation of high risk patients after coronary bypass grafting: a prospective, double blinded, placebo controlled, randomized study. European Heart Journal, 27, 1584–1591.PubMedCrossRef Budeus, M., Hennersdorf, M., Perings, S., et al. (2006). Amiodarone prophylaxis for atrial fibrillation of high risk patients after coronary bypass grafting: a prospective, double blinded, placebo controlled, randomized study. European Heart Journal, 27, 1584–1591.PubMedCrossRef
18.
go back to reference Açil, T., Cölkesen, Y., Türköz, R., et al. (2007). Value of preoperative echocardiography in the prediction of postoperative atrial fibrillation following isolated coronary artery bypass grafting. The American Journal of Cardiology, 100(9), 1383–1386.PubMedCrossRef Açil, T., Cölkesen, Y., Türköz, R., et al. (2007). Value of preoperative echocardiography in the prediction of postoperative atrial fibrillation following isolated coronary artery bypass grafting. The American Journal of Cardiology, 100(9), 1383–1386.PubMedCrossRef
19.
go back to reference Osranek, M., Fatema, K., Qaddoura, F., et al. (2006). Left atrial volume predicts the risk of atrial fibrillation after cardiac surgery: a prospective study. Journal of the American College of Cardiology, 48, 779–786.PubMedCrossRef Osranek, M., Fatema, K., Qaddoura, F., et al. (2006). Left atrial volume predicts the risk of atrial fibrillation after cardiac surgery: a prospective study. Journal of the American College of Cardiology, 48, 779–786.PubMedCrossRef
20.
go back to reference Davies, M., & Pomerance, A. (1972). Pathology of atrial fibrillation in man. British Heart Journal, 34, 520–525.PubMedCrossRef Davies, M., & Pomerance, A. (1972). Pathology of atrial fibrillation in man. British Heart Journal, 34, 520–525.PubMedCrossRef
21.
go back to reference Nardi, F., Diena, M., Caimmi, P. P., Iraghi, G., Lazzero, M., Cerin, G., et al. (2012). Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting. Journal of Cardiac Surgery, 27(1), 128–135.PubMedCrossRef Nardi, F., Diena, M., Caimmi, P. P., Iraghi, G., Lazzero, M., Cerin, G., et al. (2012). Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting. Journal of Cardiac Surgery, 27(1), 128–135.PubMedCrossRef
22.
go back to reference Gaspo, R., Bosch, R. F., Talajic, M., & Nattel, S. (1997). Functional mechanisms underlying tachycardia-induced sustained atrial fibrillation in a chronic dog model. Circulation, 96, 4027–4035.PubMedCrossRef Gaspo, R., Bosch, R. F., Talajic, M., & Nattel, S. (1997). Functional mechanisms underlying tachycardia-induced sustained atrial fibrillation in a chronic dog model. Circulation, 96, 4027–4035.PubMedCrossRef
23.
go back to reference Choi, J. I., Ryu, K., Park, E., Benser, M. E., Jang, J. K., Lee, H. S., et al. (2010). Atrial activation time and pattern of linear triple-site vs. single-site atrial pacing after cardioversion in patients with atrial fibrillation. Europace, 12, 508–516.PubMedCrossRef Choi, J. I., Ryu, K., Park, E., Benser, M. E., Jang, J. K., Lee, H. S., et al. (2010). Atrial activation time and pattern of linear triple-site vs. single-site atrial pacing after cardioversion in patients with atrial fibrillation. Europace, 12, 508–516.PubMedCrossRef
24.
go back to reference De Vos, C. B., Weijs, B., Crijns, H. J., Cheriex, E. C., Palmans, A., Habets, J., et al. (2009). Atrial tissue Doppler imaging for prediction of new-onset atrial fibrillation. Heart, 95, 835–840.PubMedCrossRef De Vos, C. B., Weijs, B., Crijns, H. J., Cheriex, E. C., Palmans, A., Habets, J., et al. (2009). Atrial tissue Doppler imaging for prediction of new-onset atrial fibrillation. Heart, 95, 835–840.PubMedCrossRef
Metadata
Title
Predictive value of total atrial conduction time measured with tissue Doppler imaging for postoperative atrial fibrillation after coronary artery bypass surgery
Authors
Mehmet Fatih Özlü
Kemalettin Erdem
Gülhanım Kırış
Ali İhsan Parlar
Abdullah Demirhan
Selim Suzi Ayhan
Alim Erdem
Serkan Öztürk
Ümit Yaşar Tekelioğlu
Mehmet Yazıcı
Publication date
01-06-2013
Publisher
Springer US
Published in
Journal of Interventional Cardiac Electrophysiology / Issue 1/2013
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-012-9756-4

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