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Journal of Assisted Reproduction and Genetics

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Open Access 01-05-2013 | ASSISTED REPRODUCTION TECHNOLOGIES

The use of morphokinetic parameters to select all embryos with full capacity to implant

Authors: Sandrine Chamayou, Pasquale Patrizio, Giorgia Storaci, Venera Tomaselli, Carmelita Alecci, Carmen Ragolia, Claudia Crescenzo, Antonino Guglielmino

Published in: Journal of Assisted Reproduction and Genetics | Issue 5/2013

Abstract

Purpose

Embryo kinetics analysis is an emerging tool for selecting embryo(s) for transfer. The aim of the present study was to determine morphokinetic parameters easily usable in the laboratory and predictive of embryo development and, most importantly, of embryo competence in producing a clinical pregnancy after day 5 transfer.

Methods

A retrospective time-lapse monitoring analysis of morphokinetic parameters for 72 fully implanted embryos (group A) were compared to 106 non-implanted embryos (group B), and to 66 embryos with arrested development from the same pool of group A. All the embryos were from 78 patients undergoing ICSI treatment and day 5 embryo transfers.

Results

A day 3 embryo will develop into a viable blastocyst if the following ranges of morphokinetic parameters are met: t1 (between 18.4 h and 30.9 h post-ICSI), t2 (21.4–34.8 h), t4 (33.1–57.2 h), t7 (46.1–82.5 h), t8 (46.4–97.8 h), tC-tF (7.7–22.9 h) and s3 (0.7–30.8 h). On day 5 embryos with the highest probability to implant are those with a cc3 between 9.7 h and 21 h.

Conclusions

Morphokinetic parameters are helpful to make appropriate decisions for the disposition of each embryo. It is recommended that each laboratory should determine its own ranges of in vitro development (IVD-MKP) and implantation-associated (IMP-MKP) morphokinetic parameters.

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Title: The use of morphokinetic parameters to select all embryos with full capacity to implant
Authors: Sandrine Chamayou
Pasquale Patrizio
Giorgia Storaci
Venera Tomaselli
Carmelita Alecci
Carmen Ragolia
Claudia Crescenzo
Antonino Guglielmino
Publication date: 01-05-2013
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 5/2013
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-013-9992-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The use of morphokinetic parameters to select all embryos with full capacity to implant

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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