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Published in: Journal of Assisted Reproduction and Genetics 7/2010

01-07-2010 | Assisted Reproduction

Reproduction beyond menopause: how old is too old for assisted reproductive technology?

Authors: David Banh, Dara L. Havemann, John Y. Phelps

Published in: Journal of Assisted Reproduction and Genetics | Issue 7/2010

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Abstract

Background

Due to the recent media attention on postmenopausal women giving birth, there has been an increased scrutiny on the utility and safety of assisted reproductive technology in postmenopausal women.

Objective

The purpose of this commentary is to discuss the following: 1) the limitations and complications of ART in women of advanced reproductive age; 2) the balance between the welfare of the mother and that of the child; 3) the double standards of advanced reproductive age; and 4) the importance of financial and social support systems and preconception counseling with advanced reproductive age.

Conclusion

When providing in-vitro fertilization services to women of advanced reproductive age, special considerations must be given to ensure the welfare of mother and the child and that the principles of beneficence and nonmaleficence are guaranteed.
Literature
3.
go back to reference Check JH, Nowroozi K, Barnea ER, Shaw KJ, Sauer MV. Successful delivery after age 50: a report of two cases as a result of oocyte donation. Obstet Gynecol. 1993;81:835–6.PubMed Check JH, Nowroozi K, Barnea ER, Shaw KJ, Sauer MV. Successful delivery after age 50: a report of two cases as a result of oocyte donation. Obstet Gynecol. 1993;81:835–6.PubMed
4.
go back to reference Antinori S, Versaci C, Gholami GH, Panci C, Caffa B. Oocyte donation in menopausal women. Hum Reprod. 1993;8:1487.PubMed Antinori S, Versaci C, Gholami GH, Panci C, Caffa B. Oocyte donation in menopausal women. Hum Reprod. 1993;8:1487.PubMed
5.
go back to reference Sauer MV, Paulson RJ, Lobo RA. Pregnancy after age 50: application of oocyte donation to women after natural menopause. Lancet. 1993;341:321–3.CrossRefPubMed Sauer MV, Paulson RJ, Lobo RA. Pregnancy after age 50: application of oocyte donation to women after natural menopause. Lancet. 1993;341:321–3.CrossRefPubMed
6.
go back to reference Sauer MV, Paulson RJ, Lobo RA. Pregnancy in women 50 or more years of age: outcomes of 22 consecutively established pregnancies from oocyte donation. Fertil Steril. 1995;64:111–5.PubMed Sauer MV, Paulson RJ, Lobo RA. Pregnancy in women 50 or more years of age: outcomes of 22 consecutively established pregnancies from oocyte donation. Fertil Steril. 1995;64:111–5.PubMed
7.
go back to reference Daar JF. Reproductive technologies and the law. Newark: LexisNexis/Matthew Bender; 2005. Daar JF. Reproductive technologies and the law. Newark: LexisNexis/Matthew Bender; 2005.
8.
go back to reference Faddy MJ, Gosden RG, Gougeon A, Richardson SJ, Nelson JF. Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause. Hum Reprod. 1992;7:1342–6.PubMed Faddy MJ, Gosden RG, Gougeon A, Richardson SJ, Nelson JF. Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause. Hum Reprod. 1992;7:1342–6.PubMed
9.
go back to reference Arias E. United States life tables, 2004. National vital statistics reports. Hyattsville: National Center for Health Statistics; 2007. Arias E. United States life tables, 2004. National vital statistics reports. Hyattsville: National Center for Health Statistics; 2007.
10.
go back to reference World Health Organization. The global burden of disease: 2004 update. Geneva: WHO; 2008. World Health Organization. The global burden of disease: 2004 update. Geneva: WHO; 2008.
11.
go back to reference Roy A. Specificity of risk factors for depression. Am J Psychiatry. 1981;138:959–61.PubMed Roy A. Specificity of risk factors for depression. Am J Psychiatry. 1981;138:959–61.PubMed
12.
go back to reference Melhem NM, Walker M, Moritz G, Brent DA. Antecedents and sequelae of sudden parental death in offspring and surviving caregivers. Arch Pediatr Adolesc Med. 2008;162:403–10.CrossRefPubMed Melhem NM, Walker M, Moritz G, Brent DA. Antecedents and sequelae of sudden parental death in offspring and surviving caregivers. Arch Pediatr Adolesc Med. 2008;162:403–10.CrossRefPubMed
13.
go back to reference Salihu HM, Shumpert MN, Slay M, Kirby RS, Alexander GR. Childbearing beyond maternal age 50 and fetal outcomes in the United States. Obstet Gynecol. 2003;102:1006–14.CrossRefPubMed Salihu HM, Shumpert MN, Slay M, Kirby RS, Alexander GR. Childbearing beyond maternal age 50 and fetal outcomes in the United States. Obstet Gynecol. 2003;102:1006–14.CrossRefPubMed
14.
go back to reference Nabukera S, Wingate MS, Alexander GR, Salihu HM. First-time births among women 30 years and older in the United States: patterns and risk of adverse outcomes. J Reprod Med. 2006;51:676–82.PubMed Nabukera S, Wingate MS, Alexander GR, Salihu HM. First-time births among women 30 years and older in the United States: patterns and risk of adverse outcomes. J Reprod Med. 2006;51:676–82.PubMed
15.
go back to reference Human Fertilisation and Embryology Authority. Code of practice. 8th ed. London: Human Fertilization and Embryology Authority; 2009. Human Fertilisation and Embryology Authority. Code of practice. 8th ed. London: Human Fertilization and Embryology Authority; 2009.
17.
go back to reference Centers for Disease Control and Prevention. The burden of chronic diseases and their risk factors: national and state perspectives 2002. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention; 2002. Centers for Disease Control and Prevention. The burden of chronic diseases and their risk factors: national and state perspectives 2002. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention; 2002.
18.
go back to reference U.S. Department of Health and Human Services: Mental health: a report of the surgeon general—executive summary. Rockville: U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services, National Institutes of Health, National Institute of Mental Health; 1999. U.S. Department of Health and Human Services: Mental health: a report of the surgeon general—executive summary. Rockville: U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services, National Institutes of Health, National Institute of Mental Health; 1999.
19.
go back to reference Unverzagt FW, Gao S, Baiyewu O, Ogunniyi AO, Gureje O, Perkins A, et al. Prevalence of cognitive impairment. Neurology. 2001;57:1655–62.PubMed Unverzagt FW, Gao S, Baiyewu O, Ogunniyi AO, Gureje O, Perkins A, et al. Prevalence of cognitive impairment. Neurology. 2001;57:1655–62.PubMed
20.
Metadata
Title
Reproduction beyond menopause: how old is too old for assisted reproductive technology?
Authors
David Banh
Dara L. Havemann
John Y. Phelps
Publication date
01-07-2010
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 7/2010
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-010-9418-3

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