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01-09-2012

Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management

Authors: Khalil Murad, Dalane W. Kitzman

Published in: Heart Failure Reviews | Issue 4-5/2012

Abstract

Heart failure (HF) in the elderly is a major public health problem, and its prevalence is rising. Outcomes of HF in the elderly have not changed in the past 2 decades despite the introduction of novel HF therapies. This may be due to the combined impact of multiple comorbidities and frailty. The majority of elderly patients with HF are frail with multiple comorbidities. These comorbidities, along with frailty, contribute to the poor outcome of HF in the elderly and pose independent management challenges. More research is needed to better understand the interaction between frailty and multiple comorbidities and the mechanisms by which they impact HF and its management; develop prognostic tools that incorporate frailty and multiple comorbidities and provide more accurate prediction of outcomes; test available treatments in typical elderly patients; and develop and test novel interventions that directly address the adverse impact of multiple comorbidities and frailty.

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Title: Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management
Authors: Khalil Murad
Dalane W. Kitzman
Publication date: 01-09-2012
Publisher: Springer US
Published in: Heart Failure Reviews / Issue 4-5/2012
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI: https://doi.org/10.1007/s10741-011-9258-y

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