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Published in: Digestive Diseases and Sciences 12/2010

01-12-2010 | Original Article

Fully Covered Alimaxx Esophageal Metal Stents in the Endoscopic Treatment of Benign Esophageal Diseases

Published in: Digestive Diseases and Sciences | Issue 12/2010

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Abstract

Background

Expandable esophageal stents are widely used for the palliation of dysphagia in patients with esophageal cancer and are also beginning to be used in patients with benign esophageal diseases such as refractory strictures and fistulas. There is concern regarding the increased risk of migration of the fully covered Alimaxx metal esophageal stent and experience with this stent in benign esophageal pathology has been reported in only a small series of patients.

Aims

To evaluate the technical success in placement and removal, efficacy and complications of the Alimaxx esophageal stent for benign esophageal diseases.

Methods

Our endoscopy database was retrospectively reviewed from 1/2003 to 2/2009 to identify patients with Alimaxx esophageal stent placement for benign diseases. Chart review was performed for age, gender, indication, site of the lesion, success of placement, outcome, and incidence of complications.

Results

Twenty-eight stents were successfully placed in 14 patients with benign esophageal diseases (mean: two stents/patient; range 1–7). Indications included esophageal fistula in seven (50%) and benign strictures in 7/14 (50%). Dysphagia improved in all patients while the fistula resolved in 6/7 (85.8%) patients. Complications related to stents included pain (2/28, 7%), stent related gastric ulcer (1/28, 4%), nausea and vomiting (3/21, 11%) and stent migration (11/28, 39%). All migrated stents were successfully endoscopically retrieved.

Conclusions

The fully covered and removable Alimaxx stent is effective in the endoscopic management of benign esophageal strictures or fistulas, despite its relatively high rate of migration. Stent migration was successfully managed endoscopically without complications.
Literature
1.
go back to reference Schubert D, Scheidbach H, Kuhn R, et al. Endoscopic treatment of thoracic esophageal anastomotic leaks by using silicone-covered, self-expanding polyester stents. Gastrointest Endosc. 2005;61:891–896.CrossRefPubMed Schubert D, Scheidbach H, Kuhn R, et al. Endoscopic treatment of thoracic esophageal anastomotic leaks by using silicone-covered, self-expanding polyester stents. Gastrointest Endosc. 2005;61:891–896.CrossRefPubMed
2.
go back to reference Davies N, Thomas HG, Eyre-Brook IA. Palliation of dysphagia from inoperable oesophageal carcinoma using Atkinson tubes or self-expanding metal stents. Ann R Coll Surg Engl. 1998;80:394–397.PubMed Davies N, Thomas HG, Eyre-Brook IA. Palliation of dysphagia from inoperable oesophageal carcinoma using Atkinson tubes or self-expanding metal stents. Ann R Coll Surg Engl. 1998;80:394–397.PubMed
3.
go back to reference Jagannath S, Canto MI. Endoscopic therapy for advanced esophageal cancer. In: Kochman ML, ed. Endoscopic Oncology: Gastrointestinal Endoscopy and Cancer Management. Totowa, NJ: Humana Press; 2006:53–62. Jagannath S, Canto MI. Endoscopic therapy for advanced esophageal cancer. In: Kochman ML, ed. Endoscopic Oncology: Gastrointestinal Endoscopy and Cancer Management. Totowa, NJ: Humana Press; 2006:53–62.
4.
go back to reference Bethge N, Vakil N. A prospective trial of a new self-expanding plastic stent for malignant esophageal obstruction. Am J Gastroenterol. 2001;96:1350–1354.CrossRefPubMed Bethge N, Vakil N. A prospective trial of a new self-expanding plastic stent for malignant esophageal obstruction. Am J Gastroenterol. 2001;96:1350–1354.CrossRefPubMed
5.
go back to reference Evrard S, Le Moine O, Lazaraki G, Dormann A, El Nakadi I, Deviere J. Self-expanding plastic stents for benign esophageal lesions. Gastrointest Endosc. 2004;60:894–900.CrossRefPubMed Evrard S, Le Moine O, Lazaraki G, Dormann A, El Nakadi I, Deviere J. Self-expanding plastic stents for benign esophageal lesions. Gastrointest Endosc. 2004;60:894–900.CrossRefPubMed
6.
go back to reference Homs MY, Essink-Bot ML, Borsboom GJ, Steyerberg EW, Siersema PD. Quality of life after palliative treatment for oesophageal carcinoma—a prospective comparison between stent placement and single dose brachytherapy. Eur J Cancer. 2004;40:1862–1871.CrossRefPubMed Homs MY, Essink-Bot ML, Borsboom GJ, Steyerberg EW, Siersema PD. Quality of life after palliative treatment for oesophageal carcinoma—a prospective comparison between stent placement and single dose brachytherapy. Eur J Cancer. 2004;40:1862–1871.CrossRefPubMed
7.
go back to reference Yeaton P, Shami V, Kahaleh M, et al. Reduction in complications leading to recurrent dysphagia using a hybrid esophageal stent—a multi-center retrospective analysis. Gastrointest Endosc. 2007;65:AB280.CrossRef Yeaton P, Shami V, Kahaleh M, et al. Reduction in complications leading to recurrent dysphagia using a hybrid esophageal stent—a multi-center retrospective analysis. Gastrointest Endosc. 2007;65:AB280.CrossRef
8.
go back to reference Uitdehaag MJ, Hooft JE, Verschuur EM, et al. A fully-covered stent (Alimaxx-E) for the palliation of malignant dysphagia: a prospective follow-up study. Gastrointest Endosc. 2009;70(6):1082–1089.CrossRefPubMed Uitdehaag MJ, Hooft JE, Verschuur EM, et al. A fully-covered stent (Alimaxx-E) for the palliation of malignant dysphagia: a prospective follow-up study. Gastrointest Endosc. 2009;70(6):1082–1089.CrossRefPubMed
9.
go back to reference Yeaton P, Shami V. Removal of covered, self-expanding nitinol stents in the treatment of benign esophageal diseases. Gastrointest Endosc. 2007;65:AB279.CrossRef Yeaton P, Shami V. Removal of covered, self-expanding nitinol stents in the treatment of benign esophageal diseases. Gastrointest Endosc. 2007;65:AB279.CrossRef
10.
go back to reference Lakhtakia S, Reddy N, Dua K. Refractory benign esophageal strictures: continuous, non-permanent dilation with a self-expandable metal esophageal stent (Alimaxx-E). Gastrointest Endosc. 2008;65:AB284.CrossRef Lakhtakia S, Reddy N, Dua K. Refractory benign esophageal strictures: continuous, non-permanent dilation with a self-expandable metal esophageal stent (Alimaxx-E). Gastrointest Endosc. 2008;65:AB284.CrossRef
11.
go back to reference Eloubeidi MA, Lopes TL. Novel removable internally fully covered self-expanding metal esophageal stent: feasibility, technique of removal, and tissue response in humans. Am J Gastroenterol. 2009;104:1374–1381.CrossRefPubMed Eloubeidi MA, Lopes TL. Novel removable internally fully covered self-expanding metal esophageal stent: feasibility, technique of removal, and tissue response in humans. Am J Gastroenterol. 2009;104:1374–1381.CrossRefPubMed
12.
go back to reference Pennathur A, Chang AC, McGrath KM, et al. Polyflex expandable stents in the treatment of esophageal disease: initial experience. Ann Thorac Surg. 2008;85:1968–1972.CrossRefPubMed Pennathur A, Chang AC, McGrath KM, et al. Polyflex expandable stents in the treatment of esophageal disease: initial experience. Ann Thorac Surg. 2008;85:1968–1972.CrossRefPubMed
13.
go back to reference Siersema PD, Hop WC, van Blankenstein M, et al. A comparison of 3 types of covered metal stents for the palliation of patients with dysphagia caused by esophagogastric carcinoma: a prospective, randomized study. Gastrointest Endosc. 2001;54:145–153.PubMed Siersema PD, Hop WC, van Blankenstein M, et al. A comparison of 3 types of covered metal stents for the palliation of patients with dysphagia caused by esophagogastric carcinoma: a prospective, randomized study. Gastrointest Endosc. 2001;54:145–153.PubMed
14.
go back to reference Homs MY, Steyerberg EW, Kuipers EJ, et al. Causes and treatment of recurrent dysphagia after self-expanding metal stent placement for palliation of esophageal carcinoma. Endoscopy. 2004;36(10):880–886.CrossRefPubMed Homs MY, Steyerberg EW, Kuipers EJ, et al. Causes and treatment of recurrent dysphagia after self-expanding metal stent placement for palliation of esophageal carcinoma. Endoscopy. 2004;36(10):880–886.CrossRefPubMed
15.
go back to reference Conio M, Repici A, Battaglia G, et al. A randomized prospective comparison of self-expandable plastic stents and partially covered self-expandable metal stents in the palliation of malignant esophageal dysphagia. Am J Gastroenterol. 2007;102(12):2667–2677.CrossRefPubMed Conio M, Repici A, Battaglia G, et al. A randomized prospective comparison of self-expandable plastic stents and partially covered self-expandable metal stents in the palliation of malignant esophageal dysphagia. Am J Gastroenterol. 2007;102(12):2667–2677.CrossRefPubMed
Metadata
Title
Fully Covered Alimaxx Esophageal Metal Stents in the Endoscopic Treatment of Benign Esophageal Diseases
Publication date
01-12-2010
Published in
Digestive Diseases and Sciences / Issue 12/2010
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-010-1415-y

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