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Published in: The International Journal of Cardiovascular Imaging 2/2010

01-12-2010 | Original paper

Comprehensive evaluation of patients suspected with deep vein thrombosis using indirect CT venography with multi-detector row technology: from protocol to interpretation

Authors: Yen-Ting Lin, I-Chen Tsai, Wei-Lin Tsai, Min-Chi Chen, Pao-Chun Lin, Si-Wa Chan, Clayton Chi-Chang Chen

Published in: The International Journal of Cardiovascular Imaging | Special Issue 2/2010

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Abstract

With the increased availability of multi-detector row CT, indirect CT venography has become an important non-invasive image modality for patients with suspected deep vein thrombosis. Use of indirect CT venography can not only diagnose/exclude deep vein thrombosis, but can also determine if there are other anomalies or diseases which might contribute to the patient’s symptoms. In this pictorial essay, we introduce the scanning protocol, post-processing techniques, and interpretation algorithm used in widely available 64 multi-detector row technology. We discuss several cases, including deep vein thrombosis in acute and chronic stages, anatomic variation, vena cava filter, and collateral veins. Lastly, we consider alternative diagnoses including varicose veins, infection, prosthesis failure of arthroplasty, traumatic vessel injury, and other musculoskeletal conditions. Radiologists should be familiar with the comprehensive interpretation of indirect CT venography to facilitate differential diagnosis and further treatment decision.
Literature
1.
go back to reference Loud PA, Katz DS, Klippenstein DL et al (2000) Combined CT venography and pulmonary angiography in suspected thromboembolic disease: diagnostic accuracy for deep venous evaluation. AJR Am J Roentgenol 174(1):61–65PubMed Loud PA, Katz DS, Klippenstein DL et al (2000) Combined CT venography and pulmonary angiography in suspected thromboembolic disease: diagnostic accuracy for deep venous evaluation. AJR Am J Roentgenol 174(1):61–65PubMed
2.
go back to reference Hull R, Hirsh J, Sackett DL et al (1981) Clinical validity of a negative venogram in patients with clinically suspected venous thrombosis. Circulation 64(3):622–625PubMed Hull R, Hirsh J, Sackett DL et al (1981) Clinical validity of a negative venogram in patients with clinically suspected venous thrombosis. Circulation 64(3):622–625PubMed
3.
go back to reference Tovey C, Wyatt S (2003) Diagnosis, investigation, and management of deep vein thrombosis. BMJ 326(7400):1180–1184CrossRefPubMed Tovey C, Wyatt S (2003) Diagnosis, investigation, and management of deep vein thrombosis. BMJ 326(7400):1180–1184CrossRefPubMed
4.
go back to reference Useche JN, de Castro AM, Galvis GE et al (2008) Use of US in the evaluation of patients with symptoms of deep venous thrombosis of the lower extremities. Radiographics 28(6):1785–1797CrossRefPubMed Useche JN, de Castro AM, Galvis GE et al (2008) Use of US in the evaluation of patients with symptoms of deep venous thrombosis of the lower extremities. Radiographics 28(6):1785–1797CrossRefPubMed
5.
go back to reference Duewell S, Hagspiel KD, Zuber J et al (1992) Swollen lower extremity: role of MR imaging. Radiology 184(1):227–231PubMed Duewell S, Hagspiel KD, Zuber J et al (1992) Swollen lower extremity: role of MR imaging. Radiology 184(1):227–231PubMed
6.
go back to reference Ciccotosto C, Goodman LR, Washington L et al (2002) Indirect CT venography following CT pulmonary angiography: spectrum of CT findings. J Thorac Imaging 17(1):18–27CrossRefPubMed Ciccotosto C, Goodman LR, Washington L et al (2002) Indirect CT venography following CT pulmonary angiography: spectrum of CT findings. J Thorac Imaging 17(1):18–27CrossRefPubMed
7.
go back to reference Kalva SP, Jagannathan JP, Hahn PF et al (2008) Venous thromboembolism: indirect CT venography during CT pulmonary angiography—should the pelvis be imaged? Radiology 246(2):605–611CrossRefPubMed Kalva SP, Jagannathan JP, Hahn PF et al (2008) Venous thromboembolism: indirect CT venography during CT pulmonary angiography—should the pelvis be imaged? Radiology 246(2):605–611CrossRefPubMed
8.
go back to reference Katz DS, Loud PA, Bruce D et al (2002) Combined CT venography and pulmonary angiography: a comprehensive review. Radiographics 22 Spec No:S3–S19; discussion S20–S24 Katz DS, Loud PA, Bruce D et al (2002) Combined CT venography and pulmonary angiography: a comprehensive review. Radiographics 22 Spec No:S3–S19; discussion S20–S24
9.
go back to reference Oguzkurt L, Tercan F, Pourbagher MA et al (2005) Computed tomography findings in 10 cases of iliac vein compression (May-Thurner) syndrome. Eur J Radiol 55(3):421–425CrossRefPubMed Oguzkurt L, Tercan F, Pourbagher MA et al (2005) Computed tomography findings in 10 cases of iliac vein compression (May-Thurner) syndrome. Eur J Radiol 55(3):421–425CrossRefPubMed
10.
go back to reference Chee YL, Culligan DJ, Watson HG (2001) Inferior vena cava malformation as a risk factor for deep venous thrombosis in the young. Br J Haematol 114(4):878–880CrossRefPubMed Chee YL, Culligan DJ, Watson HG (2001) Inferior vena cava malformation as a risk factor for deep venous thrombosis in the young. Br J Haematol 114(4):878–880CrossRefPubMed
11.
go back to reference Geerts WH, Bergqvist D, Pineo GF et al (2008) Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133(6 Suppl):381S–453SCrossRefPubMed Geerts WH, Bergqvist D, Pineo GF et al (2008) Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133(6 Suppl):381S–453SCrossRefPubMed
12.
go back to reference Sud R, Khorana AA (2009) Cancer-associated thrombosis: risk factors, candidate biomarkers and risk model. Thromb Res 123 Suppl 4:S18–S21CrossRefPubMed Sud R, Khorana AA (2009) Cancer-associated thrombosis: risk factors, candidate biomarkers and risk model. Thromb Res 123 Suppl 4:S18–S21CrossRefPubMed
13.
go back to reference Vazquez SR, Freeman A, VanWoerkom RC et al (2009) Contemporary issues in the prevention and management of postthrombotic syndrome. Ann Pharmacother 43(11):1824–1835CrossRefPubMed Vazquez SR, Freeman A, VanWoerkom RC et al (2009) Contemporary issues in the prevention and management of postthrombotic syndrome. Ann Pharmacother 43(11):1824–1835CrossRefPubMed
14.
15.
go back to reference Baskin JL, Pui CH, Reiss U et al (2009) Management of occlusion and thrombosis associated with long-term indwelling central venous catheters. Lancet 374(9684):159–169CrossRefPubMed Baskin JL, Pui CH, Reiss U et al (2009) Management of occlusion and thrombosis associated with long-term indwelling central venous catheters. Lancet 374(9684):159–169CrossRefPubMed
16.
go back to reference Decousus H, Leizorovicz A, Parent F et al (1998) A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prévention du Risque d’Embolie Pulmonaire par Interruption Cave Study Group. N Engl J Med 338(7):409–415CrossRefPubMed Decousus H, Leizorovicz A, Parent F et al (1998) A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prévention du Risque d’Embolie Pulmonaire par Interruption Cave Study Group. N Engl J Med 338(7):409–415CrossRefPubMed
17.
go back to reference PREPIC Study Group (2005) Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (Prevention du Risque d’Embolie Pulmonaire par Interruption Cave) randomized study. Circulation 112(3):416–422CrossRef PREPIC Study Group (2005) Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (Prevention du Risque d’Embolie Pulmonaire par Interruption Cave) randomized study. Circulation 112(3):416–422CrossRef
18.
go back to reference Jung SC, Lee W, Chung JW et al (2009) Unusual causes of varicose veins in the lower extremities: CT venographic and Doppler US findings. Radiographics 29(2):525–536CrossRefPubMed Jung SC, Lee W, Chung JW et al (2009) Unusual causes of varicose veins in the lower extremities: CT venographic and Doppler US findings. Radiographics 29(2):525–536CrossRefPubMed
19.
go back to reference Hadjis NS, Carr DH, Banks L et al (1985) The role of CT in the diagnosis of primary lymphedema of the lower limb. AJR Am J Roentgenol 144(2):361–364PubMed Hadjis NS, Carr DH, Banks L et al (1985) The role of CT in the diagnosis of primary lymphedema of the lower limb. AJR Am J Roentgenol 144(2):361–364PubMed
20.
go back to reference Fayad LM, Carrino JA, Fishman EK (2007) Musculoskeletal infection: role of CT in the emergency department. Radiographics 27(6):1723–1736CrossRefPubMed Fayad LM, Carrino JA, Fishman EK (2007) Musculoskeletal infection: role of CT in the emergency department. Radiographics 27(6):1723–1736CrossRefPubMed
21.
go back to reference Turecki MB, Taljanovic MS, Stubbs AY et al (2009) Imaging of musculoskeletal soft tissue infections. Skeletal Radiol (Epub ahead of print). doi:10.1007/s0025600907800 Turecki MB, Taljanovic MS, Stubbs AY et al (2009) Imaging of musculoskeletal soft tissue infections. Skeletal Radiol (Epub ahead of print). doi:10.​1007/​s0025600907800
22.
go back to reference Rabin DN, Smith C, Kubicka RA et al (1987) Problem prostheses: the radiologic evaluation of total joint replacement. Radiographics 7(6):1107–1127PubMed Rabin DN, Smith C, Kubicka RA et al (1987) Problem prostheses: the radiologic evaluation of total joint replacement. Radiographics 7(6):1107–1127PubMed
23.
go back to reference Selby R, Geerts W, Ofosu FA et al (2009) Hypercoagulability after trauma: hemostatic changes and relationship to venous thromboembolism. Thromb Res 124(3):281–287CrossRefPubMed Selby R, Geerts W, Ofosu FA et al (2009) Hypercoagulability after trauma: hemostatic changes and relationship to venous thromboembolism. Thromb Res 124(3):281–287CrossRefPubMed
24.
go back to reference Tait GB, Bach F, Dixon J (1965) Acute synovial rupture: further observations. Ann Rheum Dis 24:273–277CrossRefPubMed Tait GB, Bach F, Dixon J (1965) Acute synovial rupture: further observations. Ann Rheum Dis 24:273–277CrossRefPubMed
25.
go back to reference Tatsumura M, Mishima H, Shiina I et al (2008) Femoral nerve palsy caused by a huge iliopectineal synovitis extending to the iliac fossa in a rheumatoid arthritis case. Mod Rheumatol 18(1):81–85CrossRefPubMed Tatsumura M, Mishima H, Shiina I et al (2008) Femoral nerve palsy caused by a huge iliopectineal synovitis extending to the iliac fossa in a rheumatoid arthritis case. Mod Rheumatol 18(1):81–85CrossRefPubMed
Metadata
Title
Comprehensive evaluation of patients suspected with deep vein thrombosis using indirect CT venography with multi-detector row technology: from protocol to interpretation
Authors
Yen-Ting Lin
I-Chen Tsai
Wei-Lin Tsai
Min-Chi Chen
Pao-Chun Lin
Si-Wa Chan
Clayton Chi-Chang Chen
Publication date
01-12-2010
Publisher
Springer Netherlands
Published in
The International Journal of Cardiovascular Imaging / Issue Special Issue 2/2010
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-010-9688-y

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